Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Meenakshi V. Gupta"'
Autor:
Ritu Aneja, Emad A. Rakha, Michelle D. Reid, Meenakshi. V. Gupta, Håvard Søiland, Emiel A. Janssen, Mohammed Aleskandarany, Michael S. Toss, Padmashree Rida, Shrikant Pawar, Nagini Maganti, Precious Imhansi-Jacob, Ishita Choudhary, Guanhao Wei, Nivya Sharma, Shaligram Sharma, Jaspreet Kaur, Karuna Mittal
Supplementary Figure from Hypoxia Drives Centrosome Amplification in Cancer Cells via HIF1α-dependent Induction of Polo-Like Kinase 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b14967d97e3c19666999c3408842d80
https://doi.org/10.1158/1541-7786.22528062.v1
https://doi.org/10.1158/1541-7786.22528062.v1
Autor:
Uma Krishnamurti, Luicane Cavalli, Karuna Mittal, Shobhna Kapoor, Sergey Klimov, Shristi Bhattarai, Komal Arora, Chakravarthy Garlapati, Meenakshi V. Gupta, Xiaoxian B Li, Upender Manne, Ritu Aneja, Deepika Wali
Publikováno v:
Cancer Research. 80:P3-05
Background: Based on the expression of androgen receptor (AR), triple-negative breast cancer (TNBC) is subdivided into AR-positive and AR-negative subtypes. Although AR is a potential therapeutic target for AR-positive TNBC, its prognostic role in TN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f9144322552219e3d2a15707330413f
https://doi.org/10.1158/1538-7445.sabcs19-p3-05-02
https://doi.org/10.1158/1538-7445.sabcs19-p3-05-02
Autor:
Håvard Søiland, Michael S. Toss, Michelle D. Reid, Meenakshi V. Gupta, Omer Kucuk, Emad A. Rakha, Meghan Jaczko, Karuna Mittal, Guanhao Wei, Emiel A. M. Janssen, Jaspreet Kaur, Ritu Aneja
Publikováno v:
Cancer Metastasis Rev
Numerical and/or structural centrosome amplification (CA) is a hallmark of cancers that is often associated with the aberrant tumor karyotypes and poor clinical outcomes. Mechanistically, CA compromises mitotic fidelity and leads to chromosome instab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e451a1bdfcfb7e4ec2874ea47977b36e
https://europepmc.org/articles/PMC7897259/
https://europepmc.org/articles/PMC7897259/
Autor:
Padmashree C.G. Rida, Emiel A. M. Janssen, Michelle D. Reid, Shaligram Sharma, Nagini Maganti, Guanhao Wei, Precious Imhansi Jacob, Meenakshi V. Gupta, Karuna Mittal, Ritu Aneja, Shrikant Pawar, Michael S. Toss, Emad A. Rakha, Da Hoon Choi, Jaspreet Kaur, Ishita Choudhary
Publikováno v:
Cancer Research. 80:3560-3560
Background: The presence of supernumerary or abnormally large centrosomes, also known as centrosome amplification (CA), drives tumor progression by enhancing chromosomal instability, and altering cellular microtubule cytoskeletons and tissue cytoarch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2999270aa4f2f4aba085c0c92776eea
https://doi.org/10.1158/1538-7445.am2020-3560
https://doi.org/10.1158/1538-7445.am2020-3560
Autor:
Meenakshi V. Gupta, Shashi Donthamsetty, Ramneet Kaur, Karuna Mittal, Da Hoon Choi, Michelle D. Reid, Chunhua Yang, Padmashree C.G. Rida, Ritu Aneja
Publikováno v:
British Journal of Cancer
Background: Docetaxel is the only FDA-approved first-line treatment for castration-resistant prostate cancer (CRPC) patients. Docetaxel treatment inevitably leads to tumour recurrence after an initial therapeutic response with generation of multinucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2cca1e1cc3eff3e9bd15769b95d805a
https://doi.org/10.1038/bjc.2017.78
https://doi.org/10.1038/bjc.2017.78
Autor:
Shristi Bhattarai, Anurag Mehta, Uma Krishnamurti, Sergey Klimov, Elaine M. Walsh, Tiffany A. Traina, Brett Baskovich, Pooja K Gajaria, Atika Dogra, Xiaoxian Bill Li, Padmashree C.G. Rida, Guilherme Cantuaria, Ceyda Sonmez Wetherilt, Meenakshi V. Gupta, Haruna A Nggada, Ian O. Ellis, Tanuja Shet, Upender Manne, Grace Callagy, Saad A Ahmed, Mohammed A. Aleskandarany, Gabriela Oprea-Ilies, Ritu Aneja, Ansa Riaz, Johnson Agboola, Abidemi Omonisi, Karuna Mittal, Emiel A. M. Janssen, Emad A. Rakha, Andrew R. Green
Publikováno v:
Cancers, Vol 11, Iss 7, p 995 (2019)
Cancers
Cancers
Background: The androgen receptor (AR) has emerged as a potential therapeutic target for AR-positive triple-negative breast cancer (TNBC). However, conflicting reports regarding AR’s prognostic role in TNBC are putting its usefulness in question. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff873b359f0d082f3ffcb14279cf1a32
https://www.mdpi.com/2072-6694/11/7/995
https://www.mdpi.com/2072-6694/11/7/995
Autor:
Tanuja Shet, Grace Callagy, Deepika Wali, Xiaoxian Bill Li, Ceyda Sonmez Wetherilt, Padmashree C.G. Rida, Upender Manne, Andrew R. Green, Mohammad A. Aleskandarany, Lauren E. McCullough, Johnson Agboola, Uma Krishnamurthi, Ritu Aneja, Ansa Riaz, Shristi Bhattarai, Meenakshi V. Gupta, Karuna Mittal, Ian O. Ellis, Anurag Mehta, Sergey Klimov, Brett Baskovich, Emiel A. M. Janssen, Rakha A. Emad
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 29:PR18-PR18
Background: African American (AA) triple-negative breast cancer (TNBC) patients experience worse clinical outcomes and exhibit 40% higher mortality rate than their European Americans (EAs) counterparts. There are currently no distinctions in inherent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79b921c8b462c653a4ec0a7ba7c1722d
https://doi.org/10.1158/1538-7755.disp18-pr18
https://doi.org/10.1158/1538-7755.disp18-pr18
Autor:
Shashikiran Donthamsetty, Guilherme Cantuaria, Vaishali Pannu, Meenakshi V. Gupta, Padmashree C.G. Rida, Michelle D. Reid, Remus Osan, Karuna Mittal, Xiaoxian Li, Michelle McBride, Sergey Klimov, Ritu Aneja
Publikováno v:
Oncotarget
Centrosome amplification (CA), a cell-biological trait, characterizes pre-neoplastic and pre-invasive lesions and is associated with tumor aggressiveness. Recent studies suggest that CA leads to malignant transformation and promotes invasion in mamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c53729f3b34877022d87a3743e3731a
https://doi.org/10.18632/oncotarget.3402
https://doi.org/10.18632/oncotarget.3402
Autor:
Emad A. Rakha, Meenakshi V. Gupta, Ceyda Sonmez Wetherilt, Shristi Bhattarai, Mohammad A. Aleskandaran, Guanhao Wei, Ian O. Ellis, Sergey Klimov, Xiaoxian Li, Ritu Aneja, Karuna Mittal, Remus Osan, Guilherme Cantuaria, Upender Manne, Padmashree C.G. Rida, Andrew A. Green, Uma Krishnamurthi
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 27:PR02-PR02
Background: Androgen receptor (AR) has emerged as a new target for treating TNBC. AR is expressed in 10-43% of TNBCs. Although there are conflicting reports in the literature about the effect of AR status on TNBC prognosis, agents targeting AR signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab3276dc3bb56d5d1541695d89dde67d
https://doi.org/10.1158/1538-7755.disp17-pr02
https://doi.org/10.1158/1538-7755.disp17-pr02
Autor:
Kristin Jonsdottir, Mohammad A. Aleskandarany, Emad A. Rakha, Da Hoon Choi, Shashi Donthamsetty, Ian O. Ellis, Michelle D. Reid, Karuna Mittal, Ritu Aneja, Meenakshi V. Gupta, Vaishali Pannu, Emiel A. M. Janssen, Brian D. Melton, Guilherme Cantuaria, Sooryanarayana Varambally, Padmashree C.G. Rida, Angela Ogden
Publikováno v:
Scientific Reports
Centrosome aberrations (CA) and abnormal mitoses are considered beacons of malignancy. Cancer cell doubling times in patient tumors are longer than in cultures, but differences in CA between tumors and cultured cells are uncharacterized. We compare m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7ac2c1e2a6a11faa4415e1ecfaf567
https://doi.org/10.1038/srep43984
https://doi.org/10.1038/srep43984