2P-FLIM unveils time-dependent metabolic shifts during osteogenic differentiation with a key role of lactate to fuel osteogenesis via glutaminolysis identified

Autor: Nuno G. B. Neto, Meenakshi Suku, David A. Hoey, Michael G. Monaghan

Publikováno v: Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-18 (2023)

Abstract Background Human mesenchymal stem cells (hMSCs) utilize discrete biosynthetic pathways to self-renew and differentiate into specific cell lineages, with undifferentiated hMSCs harbouring reliance on glycolysis and hMSCs differentiating towar

Externí odkaz: https://doaj.org/article/0b81924ff2e342fc9a86dca29aa8648e

Melt electrowriting of a biocompatible photo‐crosslinkable poly(D,L‐lactic acid)/poly(ε‐caprolactone)‐based material with tunable mechanical and functionalization properties

Autor: Conor Darroch, Giuseppe A. Asaro, Coralie Gréant, Meenakshi Suku, Nele Pien, Sandra van Vlierberghe, Michael G. Monaghan

Publikováno v: Journal of Biomedical Materials Research Part A. 111:851-862

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87041e26ecf9a81228c311a403aac6e2
https://doi.org/10.1002/jbm.a.37536

Resident macrophages and their potential in cardiac tissue engineering

Autor: Miss Meenakshi Suku, Michael G. Monaghan, Lesley M. Forrester, Manus J.P. Biggs

Publikováno v: Suku, M, Forrester, L M, Biggs, M & Monaghan, M 2021, ' Resident macrophages and their potential in cardiac tissue engineering ', Tissue engineering . https://doi.org/10.1089/ten.TEB.2021.0036

Many facets of tissue engineered models aim to understand cellular mechanisms to recapitulate in vivo behavior, study and mimic diseases for drug interventions and to provide better understanding towards improving regenerative medicine. Recent and ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf42bdf1d4ea6ff69b64e3695fc3fbb
https://hdl.handle.net/20.500.11820/4301fa78-ea21-4bce-b8e7-2ce8cf089ccc