Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Meenakshi Noll"'
Autor:
Muhsen Al-Dhalimy, Eugenio Montini, Patrice K. Held, Milton J. Finegold, Meenakshi Noll, Markus Grompe, Mark A. Kay, Stephen R. Yant, Nicolas Morcinek
Publikováno v:
Molecular Therapy. 6(6):759-769
Gene therapy applications of naked DNA constructs for genetic disorders have been limited because of lack of permanent transgene expression. This limitation, however, can be overcome by the Sleeping Beauty (SB) transposable element, which can achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f061b75209711dcf5a438bc735667f
Autor:
Francesco Galimi, Inder M Verma, Cynthia Chen, Timothy Lax, Markus Grompe, Yoshiyuki Kanazawa, Meenakshi Noll
Publikováno v:
Blood. 100:2732-2736
Fanconi anemia (FA) is an inherited cancer susceptibility syndrome caused by mutations in a DNA repair pathway including at least 6 genes(FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG). The clinical course of the disease is dominated by progressive,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232b9bdfc45c53185dbf963aaefe8db5
https://doi.org/10.1182/blood-2002-04-1245
https://doi.org/10.1182/blood-2002-04-1245
Autor:
Meenakshi Noll, Keany Rathbun, Carol Reifsteck, Timothy Lax, Milton J. Finegold, Markus Grompe, Susan B. Olson, Kevin P. Battaile, Grover C. Bagby, Raynard L. Bateman
Publikováno v:
Experimental Hematology. 30:679-688
Objective Fanconi anemia (FA) is a genetically heterogeneous disorder associated with defects in at least eight genes. The biochemical function(s) of the FA proteins are unknown, but together they define the FA pathway, which is involved in cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aeb9c36ddb0e06d8711a7b1755ba0c33
https://doi.org/10.1016/s0301-472x(02)00838-x
https://doi.org/10.1016/s0301-472x(02)00838-x
Publikováno v:
Molecular Therapy. 3(1):14-23
Fanconi anemia (FA) is an autosomal recessive disorder characterized by birth defects, increased incidence of malignancy, progressive bone marrow failure, and cellular hypersensitivity to DNA cross-linking agents. Bone marrow transplantation is thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9687025c0f68251822f3b7fd0ee3114c
Autor:
Stephen N. Jones, Cynthia Timmers, M. Stephen Meyn, Meenakshi Noll, Markus Grompe, Milton J. Finegold, Scott Houghtaling
Publikováno v:
Genesdevelopment. 17(16)
Fanconi anemia (FA) is a genetic disorder characterized by hypersensitivity to DNA damage, bone marrow failure, congenital defects, and cancer. To further investigate the in vivo function of the FA pathway, mice with a targeted deletion in the distal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c8f8a50f0f0e3e48ae67fbe8d25d91
https://pubmed.ncbi.nlm.nih.gov/12893780
https://pubmed.ncbi.nlm.nih.gov/12893780
Autor:
Meenakshi, Noll, Kevin P, Battaile, Raynard, Bateman, Timothy P, Lax, Keany, Rathbun, Carol, Reifsteck, Grover, Bagby, Milton, Finegold, Susan, Olson, Markus, Grompe
Publikováno v:
Experimental hematology. 30(7)
Fanconi anemia (FA) is a genetically heterogeneous disorder associated with defects in at least eight genes. The biochemical function(s) of the FA proteins are unknown, but together they define the FA pathway, which is involved in cellular responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::98bb035aa076c7969424a8e71d46303b
https://pubmed.ncbi.nlm.nih.gov/12135664
https://pubmed.ncbi.nlm.nih.gov/12135664
Autor:
Meenakshi Noll, Svetlana Lutsenko
Publikováno v:
IUBMB life. 49(4)
All cells have developed various mechanisms to regulate precisely the availability of important micronutrients such as zinc and copper; in many cells, this regulation is mediated by P1-type ATPases. Most of the P1-ATPases have been described very rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b755acedd49af34c0cf5651ddf14bd2d
https://pubmed.ncbi.nlm.nih.gov/10995032
https://pubmed.ncbi.nlm.nih.gov/10995032
Publikováno v:
The Journal of biological chemistry. 273(33)
Zinc is an essential trace element required for structural integrity and functional activity of numerous proteins, yet mechanisms by which cells regulate zinc concentration are poorly understood. Here, we identified a gene from Proteus mirabilis that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cfe57518c245e1dbca5d2b44004ca5b
https://pubmed.ncbi.nlm.nih.gov/9694902
https://pubmed.ncbi.nlm.nih.gov/9694902
Publikováno v:
Molecular Therapy. 11:S404
The life span of patients with Fanconi Anemia (FA) is severely shortened by bone marrow failure and malignancies and currently, allogeneic bone-marrow transplantation is the only therapeutic option. Despite the successful modeling of FA viral vector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32dbac539b915c9376531cd12d28f353
https://doi.org/10.1016/j.ymthe.2005.07.593
https://doi.org/10.1016/j.ymthe.2005.07.593
Autor:
Ryan Bennett, Jacob Giehm Mikkelsen, Mark A. Kay, Stephen R. Yant, Markus Grompe, Cindy Chen, Meenakshi Noll
Publikováno v:
Molecular Therapy. 9:S313
The life span of patients with Fanconi Anemia (FA) is severely shortened by bone marrow failure and malignancies. Currently, the only efficient therapy is bone-marrow transplantation from a matched sibling donor. Therefore, FA is considered a good ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf96f63d3752ef7b41b14a5df03844a2
https://doi.org/10.1016/j.ymthe.2004.06.723
https://doi.org/10.1016/j.ymthe.2004.06.723