Výsledky vyhledávání - "Meenakshi Duhan"

Akademický článek

Design, synthesis, conformational and molecular docking study of some novel acyl hydrazone based molecular hybrids as antimalarial and antimicrobial agents

Autor: Parvin Kumar, Kulbir Kadyan, Meenakshi Duhan, Jayant Sindhu, Vineeta Singh, Baljeet Singh Saharan

Publikováno v: Chemistry Central Journal, Vol 11, Iss 1, Pp 1-14 (2017)

Abstract Background Acyl hydrazones are an important class of heterocyclic compounds promising pharmacological characteristics. Malaria is a life-threatening mosquito-borne blood disease caused by a plasmodium parasite. In some places, malaria can be

Externí odkaz: https://doaj.org/article/09f1f50b7e774afc8d0f010a9f638dd4

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Quantitative structure activity relationship studies of novel hydrazone derivatives as α-amylase inhibitors with index of ideality of correlation

Autor: Ramesh Kumar, Khalid Hussain, Meenakshi Duhan, Parvin Kumar, Sohan Lal, Jayant Sindhu, Meena Devi, Sudhir Kumar, Rahul Singh, Ashwani Kumar

Publikováno v: Journal of Biomolecular Structure and Dynamics. 40:4933-4953

The present manuscript describes the synthesis, α-amylase inhibition, in silico studies and in-depth quantitative structure–activity relationship (QSAR) of a library of aroyl hydrazones based on be...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcec55acb19cce59e5b84e3022119afd
https://doi.org/10.1080/07391102.2020.1863861

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Silica-supported ceric ammonium nitrate (CAN): a simple, mild and solid-supported reagent for quickest oxidative aromatization of Hantzsch 1,4-dihydropyridines

Autor: Parvin Kumar, Khalid Hussain, Sohan Lal, Kulbir Kadyan, Jayant Sindhu, Meenakshi Duhan

Publikováno v: Chemical Papers. 73:1153-1162

An efficient and environmentally benign methodology for the oxidative aromatization of 1,4-dihydropyridines to their corresponding pyridine derivatives is developed. The oxidative aromatization of 1,4-dihydropyridines was explored using silica-suppor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f74e2ce7a06271f83679fda62ada497
https://doi.org/10.1007/s11696-018-0666-5

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Exploring biological efficacy of novel benzothiazole linked 2,5-disubstituted-1,3,4-oxadiazole hybrids as efficient α-amylase inhibitors: Synthesis, characterization, inhibition, molecular docking, molecular dynamics and Monte Carlo based QSAR studies

Autor: Meena Devi, Sohan Lal, Parvin Kumar, Meenakshi Duhan, Ashwani Kumar, Jayant Sindhu, Rahul Singh, Ramesh Kumar

Publikováno v: Computers in Biology and Medicine. 138:104876

In an effort to explore a class of novel antidiabetic agents, we have made an effort to synergize the α-amylase inhibitory potential of 1,3-benzothiazole and 1,3,4-oxadiazole scaffolds by combining the two into a single structure via an ether linkag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5033eceaaf0f914efc2f2f50b2ace3
https://doi.org/10.1016/j.compbiomed.2021.104876

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Correction to: Design, synthesis, conformational and molecular docking study of some novel acyl hydrazone based molecular hybrids as antimalarial and antimicrobial agents

Autor: Parvin Kumar, Kulbir Kadyan, Meenakshi Duhan, Jayant Sindhu, Vineeta Singh, Baljeet Singh Saharan

Publikováno v: Chemistry Central Journal

Acyl hydrazones are an important class of heterocyclic compounds promising pharmacological characteristics. Malaria is a life-threatening mosquito-borne blood disease caused by a plasmodium parasite. In some places, malaria can be treated and control

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7affb2752c063805aa46b6529bbcd2
https://doi.org/10.1186/s13065-018-0374-9

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Design, synthesis, conformational and molecular docking study of some novel acyl hydrazone based molecular hybrids as antimalarial and antimicrobial agents

Autor: Jayant Sindhu, Baljeet Singh Saharan, Meenakshi Duhan, Vineeta Singh, Parvin Kumar, Kulbir Kadyan

Publikováno v: Chemistry Central Journal
Chemistry Central Journal, Vol 11, Iss 1, Pp 1-14 (2017)

Background Acyl hydrazones are an important class of heterocyclic compounds promising pharmacological characteristics. Malaria is a life-threatening mosquito-borne blood disease caused by a plasmodium parasite. In some places, malaria can be treated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704eaf8885b9b0127b247e72aa0b50f5
http://europepmc.org/articles/PMC5686033

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Synthesis of novel inhibitors of α-amylase based on the thiazolidine-4-one skeleton containing a pyrazole moiety and their configurational studies

Autor: Jayant Sindhu, Parvin Kumar, Kulbir Kadyan, Meenakshi Duhan, Hitender Sharma, Sunil Kumar

Publikováno v: MedChemComm. 8(7)

Postprandial hyperglycemia can be controlled by delaying the absorption of glucose resulting from carbohydrate digestion. α-Amylase is the initiator of the hydrolysis of polysaccharides, and therefore developing α-amylase inhibitors can lead to dev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723c7277eedb82ee21ae3764d82c6a55
https://pubmed.ncbi.nlm.nih.gov/30108858

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