Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Meeli Arujõe"'
Publikováno v:
Proceedings of the Estonian Academy of Sciences, Vol 71, Iss 3, Pp 241-254 (2022)
The replacement of the α-carbon atom in an α-amino acid structure by a nitrogen atom yields alkylcarbazic acids, also known as α-aza amino acids. Although the topology of α-amino acids and α-aza amino acids is similar, their chemical a
Externí odkaz:
https://doaj.org/article/09e6a6ae9ca1483f9fd15248672d0518
Publikováno v:
Tetrahedron. 129:133161
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c90b232dd40d51c4b6d2d03a4a527d22
https://doi.org/10.1016/j.tet.2022.133161
https://doi.org/10.1016/j.tet.2022.133161
Publikováno v:
Tetrahedron Letters. 59:2010-2013
Aza-peptides are peptide analogs with potential applications as drug candidates. However, due to difficulties associated with the synthesis of these compounds, information regarding their bioactivity is very limited. Herein, we identify steric hindra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::334fcccc73c495fcaa4ca04cc6d6ce32
https://doi.org/10.1016/j.tetlet.2018.04.021
https://doi.org/10.1016/j.tetlet.2018.04.021
Publikováno v:
Tetrahedron Letters. 58:3421-3425
Aza-peptides are promising drug leads, however extensive study of their properties is hampered by low yielding aza-peptide bond formation during conventional Fmoc SPPS. The kinetics of aza-peptide bond formation in the model peptide H-Ala-AzAla-Phe-N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41cc45b58af0c89e4b938d8949e20f2a
https://doi.org/10.1016/j.tetlet.2017.07.063
https://doi.org/10.1016/j.tetlet.2017.07.063
Publikováno v:
Tetrahedron Letters. 69:152973
Aza-peptides are metabolically more stable in living organisms than their parent peptides. Despite the properties of these peptidomimetics as promising drug leads, synthesizing them is challenging and, therefore, their biological activity has been st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53dda122770a5ae71b7f11cff5959f50
https://doi.org/10.1016/j.tetlet.2021.152973
https://doi.org/10.1016/j.tetlet.2021.152973