Mesenchymal stem cell infiltration during neoplastic transformation of the human prostate

Autor: Brennen, WN, Zhang, B, Kulac, I, Kisteman, LN, Antony, L, Wang, H, Meeker, AK, De Marzo, AM, Garraway, IP, Denmeade, SR, Isaacs, JT

Publikováno v: Oncotarget, vol 8, iss 29
Brennen, WN; Zhang, B; Kulac, I; Kisteman, LN; Antony, L; Wang, H; et al.(2017). Mesenchymal stem cell infiltration during neoplastic transformation of the human prostate. ONCOTARGET, 8(29), 46710-46727. doi: 10.18632/oncotarget.17362. UCLA: Retrieved from: http://www.escholarship.org/uc/item/8372v006

Mesenchymal Stem Cells (MSCs) have been identified in prostate cancer, raising the critical question of their physical and temporal source. Therefore, MSCs were quantified and characterized in benign and malignant prostate tissue representing differe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::69c87c71d1fdd5fcc7665acc5499ed45
https://escholarship.org/uc/item/8372v006

The TERT Promoter is Polycomb-Repressed in Neuroblastoma Cells with Long Telomeres.

Autor: Graham MK; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Urology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois., Xu B; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, Tennessee., Davis C; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Meeker AK; Department of Urology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Heaphy CM; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Medicine, Boston University School of Medicine, Boston, Massachusetts., Yegnasubramanian S; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Dyer MA; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee.; Howard Hughes Medical Institute, Chevy Chase, Maryland.; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee., Zeineldin M; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Publikováno v: Cancer research communications [Cancer Res Commun] 2024 Jun 20; Vol. 4 (6), pp. 1533-1547.

Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer.

Autor: Mori JO; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA., Elhussin I; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Brennen WN; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Graham MK; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Lotan TL; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Yates CC; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., De Marzo AM; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Denmeade SR; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Yegnasubramanian S; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Nelson WG; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Denis GV; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA.; Department of Pharmacology and Experimental Therapeutics, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Platz EA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Meeker AK; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Heaphy CM; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA. heaphyc@bu.edu.; Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA. heaphyc@bu.edu.

Publikováno v: Nature reviews. Urology [Nat Rev Urol] 2024 May; Vol. 21 (5), pp. 258-273. Date of Electronic Publication: 2023 Oct 31.

DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks.

Autor: Pinto LM; DNA Repair and Chemoresistance Group, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210 Luxembourg, Luxembourg.; Faculty of Science, Technology and Communication, University of Luxembourg, L-4365 Esch-sur-Alzette, Luxembourg.; Discovery & Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS2 9JT, UK., Pailas A; DNA Repair and Chemoresistance Group, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210 Luxembourg, Luxembourg.; Faculty of Science, Technology and Communication, University of Luxembourg, L-4365 Esch-sur-Alzette, Luxembourg., Bondarchenko M; DNA Repair and Chemoresistance Group, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210 Luxembourg, Luxembourg.; Faculty of Science, Technology and Communication, University of Luxembourg, L-4365 Esch-sur-Alzette, Luxembourg., Sharma AB; DNA Repair and Chemoresistance Group, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210 Luxembourg, Luxembourg., Neumann K; DNA Repair and Chemoresistance Group, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210 Luxembourg, Luxembourg., Rizzo AJ; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA., Jeanty C; DNA Repair and Chemoresistance Group, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210 Luxembourg, Luxembourg., Nicot N; Translational Medicine Operations Hub, Luxembourg Institute of Health (LIH), Luxembourg, Luxembourg., Racca C; Institut de Pharmacologie et Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), 31077 Toulouse Cedex 4, France., Graham MK; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA., Naughton C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh EH4 1QY, UK., Liu Y; Institut Curie, PSL Research University, CNRS UMR3244, Dynamics of Genetic Information, Sorbonne Université, 75248 Paris Cedex 05, France., Chen CL; Institut Curie, PSL Research University, CNRS UMR3244, Dynamics of Genetic Information, Sorbonne Université, 75248 Paris Cedex 05, France., Meakin PJ; Discovery & Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS2 9JT, UK., Gilbert N; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh EH4 1QY, UK., Britton S; Institut de Pharmacologie et Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), 31077 Toulouse Cedex 4, France., Meeker AK; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA., Heaphy CM; Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA., Larminat F; Institut de Pharmacologie et Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), 31077 Toulouse Cedex 4, France., Van Dyck E; DNA Repair and Chemoresistance Group, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210 Luxembourg, Luxembourg.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Feb 09; Vol. 52 (3), pp. 1136-1155.

Chromogenic detection of telomere lengths in situ aids the identification of precancerous lesions in the prostate.

Autor: Ertunc O; The Department of Pathology, The Johns Hopkins University School of Medicine., Smearman E; The Department of Pathology, The Johns Hopkins University School of Medicine., Zheng Q; The Department of Pathology, The Johns Hopkins University School of Medicine., Hicks JL; The Department of Pathology, The Johns Hopkins University School of Medicine., Brosnan-Cashman JA; The Department of Pathology, The Johns Hopkins University School of Medicine., Jones T; The Department of Pathology, The Johns Hopkins University School of Medicine., Gomes-Alexandre C; The Department of Pathology, The Johns Hopkins University School of Medicine., Trabzonlu L; The Department of Pathology, The Johns Hopkins University School of Medicine., Meeker AK; The Department of Pathology, The Johns Hopkins University School of Medicine.; The Department of Urology, The Johns Hopkins University School of Medicine.; The Department of Oncology, The Johns Hopkins University School of Medicine.; The Sidney Kimmel Comprehensive Cancer Institute at Johns Hopkins, Baltimore, Maryland., De Marzo AM; The Department of Pathology, The Johns Hopkins University School of Medicine.; The Department of Urology, The Johns Hopkins University School of Medicine.; The Department of Oncology, The Johns Hopkins University School of Medicine.; The Sidney Kimmel Comprehensive Cancer Institute at Johns Hopkins, Baltimore, Maryland., Heaphy CM; The Department of Medicine, Boston University, School of Medicine and Boston Medical Center, Boston, Massachusetts.; The Department Pathology and Laboratory Medicine, Boston University, School of Medicine and Boston Medical Center, Boston, Massachusetts.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Apr 06. Date of Electronic Publication: 2023 Apr 06.