Výsledky vyhledávání - "Meeghan A O'Connor"

Breast Cancer Resistance Protein (ABCG2) in Clinical Pharmacokinetics and Drug Interactions: Practical Recommendations for Clinical Victim and Perpetrator Drug-Drug Interaction Study Design

Autor: Harma Ellens, Mary F. Paine, Maciej J. Zamek-Gliszczynski, Jack Cook, Caroline A. Lee, Mitchell E. Taub, Tasha K. Ritchie, Joseph A. Ware, Bo Feng, Meeghan A O'Connor, Aleksandra Galetin, Isabelle Ragueneau-Majlessi, Joseph W. Polli

Publikováno v: Drug Metabolism and Disposition. 43:490-509

Breast cancer resistance protein (BCRP; ABCG2) limits intestinal absorption of low-permeability substrate drugs and mediates biliary excretion of drugs and metabolites. Based on clinical evidence of BCRP-mediated drug-drug interactions (DDIs) and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a06f6950d0467683ba7779ef8a23e0
https://doi.org/10.1124/dmd.114.062174

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