Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Meegan R Anderson"'
Autor:
Roslyn A Taylor, Michael D McRaven, Ann M Carias, Meegan R Anderson, Edgar Matias, Mariluz Araínga, Edward J Allen, Kenneth A Rogers, Sandeep Gupta, Viraj Kulkarni, Samir Lakhashe, Ramon Lorenzo-Redondo, Yanique Thomas, Amanda Strickland, Francois J Villinger, Ruth M Ruprecht, Thomas J Hope
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1009855 (2021)
Vertical transmission of human immunodeficiency virus (HIV) can occur in utero, during delivery, and through breastfeeding. We utilized Positron Emission Tomography (PET) imaging coupled with fluorescent microscopy of 64Cu-labeled photoactivatable-GF
Externí odkaz:
https://doaj.org/article/910dbdac23f94dc4858ab1f0feed9b00
Autor:
Roslyn A Taylor, Sixia Xiao, Ann M Carias, Michael D McRaven, Divya N Thakkar, Mariluz Araínga, Edward J Allen, Kenneth A Rogers, Sidath C Kumarapperuma, Siqi Gong, Angela J Fought, Meegan R Anderson, Yanique Thomas, Jeffrey R Schneider, Beth Goins, Peter Fox, Francois J Villinger, Ruth M Ruprecht, Thomas J Hope
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009632 (2021)
Human immunodeficiency virus (HIV) vaccines have not been successful in clinical trials. Dimeric IgA (dIgA) in the form of secretory IgA is the most abundant antibody class in mucosal tissues, making dIgA a prime candidate for potential HIV vaccines.
Externí odkaz:
https://doaj.org/article/cc676bc5c0da4fd2ae31cd68f66412e3
Autor:
Ann M Carias, Shannon A Allen, Angela J Fought, Katarina Kotnik Halavaty, Meegan R Anderson, Maria L Jimenez, Michael D McRaven, Casey J Gioia, Tara R Henning, Ellen N Kersh, James M Smith, Lara E Pereira, Katherine Butler, S Janet M McNicholl, R Michael Hendry, Patrick F Kiser, Ronald S Veazey, Thomas J Hope
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005885 (2016)
Currently, there are mounting data suggesting that HIV-1 acquisition in women can be affected by the use of certain hormonal contraceptives. However, in non-human primate models, endogenous or exogenous progestin-dominant states are shown to increase
Externí odkaz:
https://doaj.org/article/80e89e6e2b914887bc6e62ce858014f7
Autor:
Minh H Dinh, Meegan R Anderson, Michael D McRaven, Gianguido C Cianci, Scott G McCoombe, Z L Kelley, Casey J Gioia, Angela J Fought, Alfred W Rademaker, Ronald S Veazey, Thomas J Hope
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004729 (2015)
To gain insight into female-to-male HIV sexual transmission and how male circumcision protects against this mode of transmission, we visualized HIV-1 interactions with foreskin and penile tissues in ex vivo tissue culture and in vivo rhesus macaque m
Externí odkaz:
https://doaj.org/article/8524d76e023a402b84049a15d7a210cb
Autor:
Daniel J Stieh, Danijela Maric, Z L Kelley, Meegan R Anderson, Holly Z Hattaway, Beth A Beilfuss, Katharina B Rothwangl, Ronald S Veazey, Thomas J Hope
Publikováno v:
PLoS Pathogens, Vol 10, Iss 10, p e1004440 (2014)
The majority of new HIV infections occur in women as a result of heterosexual intercourse, overcoming multiple innate barriers to infection within the mucosa. However, the avenues through which infection is established, and the nature of bottlenecks
Externí odkaz:
https://doaj.org/article/b2eaee6ec578495ab60955d2ac278b51
Autor:
Sadia Samer, Yanique Thomas, Mariluz Araínga, Crystal Carter, Lisa M. Shirreff, Muhammad S. Arif, Juan M. Avita, Ines Frank, Michael D. McRaven, Christopher T. Thuruthiyil, Veli B. Heybeli, Meegan R. Anderson, Benjamin Owen, Arsen Gaisin, Deepanwita Bose, Lacy M. Simons, Judd F. Hultquist, James Arthos, Claudia Cicala, Irini Sereti, Philip J. Santangelo, Ramon Lorenzo-Redondo, Thomas J. Hope, Francois J. Villinger, Elena Martinelli
Publikováno v:
JCI Insight, Vol 7, Iss 21 (2023)
TGF-β plays a critical role in maintaining immune cells in a resting state by inhibiting cell activation and proliferation. Resting HIV-1 target cells represent the main cellular reservoir after long-term antiretroviral therapy (ART). We hypothesize
Externí odkaz:
https://doaj.org/article/d91bfe3dac314d9ab922f0f232b2155b
Autor:
Sidath C. Kumarapperuma, Thomas J. Hope, Kenneth A. Rogers, Peter T. Fox, Edward J. Allen, Ruth M. Ruprecht, Mariluz Araínga, Francois Villinger, Yanique Thomas, Ann M. Carias, Meegan R. Anderson, Sixia Xiao, Jeffrey R. Schneider, Siqi Gong, Michael D. McRaven, Angela J. Fought, Roslyn A. Taylor, Beth Goins, Divya N. Thakkar
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009632 (2021)
PLoS Pathogens
PLoS Pathogens
Human immunodeficiency virus (HIV) vaccines have not been successful in clinical trials. Dimeric IgA (dIgA) in the form of secretory IgA is the most abundant antibody class in mucosal tissues, making dIgA a prime candidate for potential HIV vaccines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15cb5f5661d494210cc2e8472676fd8
https://doaj.org/article/cc676bc5c0da4fd2ae31cd68f66412e3
https://doaj.org/article/cc676bc5c0da4fd2ae31cd68f66412e3
Autor:
Thomas J. Hope, Amanda Strickland, Mariluz Araínga, Samir K. Lakhashe, Edward J. Allen, Yanique Thomas, Sandeep Gupta, Kenneth A. Rogers, Francois Villinger, Meegan R. Anderson, Ramon Lorenzo-Redondo, Ruth M. Ruprecht, Michael D. McRaven, Viraj Kulkarni, Roslyn A. Taylor, Edgar Matias, Ann M. Carias
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1009855 (2021)
PLoS Pathogens
PLoS Pathogens
Vertical transmission of human immunodeficiency virus (HIV) can occur in utero, during delivery, and through breastfeeding. We utilized Positron Emission Tomography (PET) imaging coupled with fluorescent microscopy of 64Cu-labeled photoactivatable-GF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d815735f1bab1b8af724e74186f3fdf1
https://doi.org/10.1371/journal.ppat.1009855
https://doi.org/10.1371/journal.ppat.1009855
Autor:
Hendrik Streeck, Jeffrey R. Schneider, Kelly M. Fahrbach, Alison E. Mahan, Bronwyn M. Gunn, Thomas J. Hope, Shiv Pillai, Bruce D. Walker, Igal Szleifer, Anna Licht, Archer D. Smith, Neil L. Kelleher, Patrick F. Kiser, David C. Malaspina, Meegan R. Anderson, Ivan Zvonar, Anais Chapel, Marcus M. Karim, Todd J. Suscovich, Arthur Y. Kim, Galit Alter, Maryam Shansab, Marcus Altfeld, Jacquelynn Tedesco, Georg M. Lauer, Arangassery Rosemary Bastian
Publikováno v:
Mucosal immunology
Transmission of HIV across mucosal barriers accounts for the majority of HIV infections worldwide. Thus, efforts aimed at enhancing protective immunity at these sites are a top priority, including increasing virus-specific antibodies (Abs) and antivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f1bb93c1fdafa0846489accf0e2c64
https://doi.org/10.1038/mi.2016.8
https://doi.org/10.1038/mi.2016.8
Publikováno v:
Proceedings of the National Academy of Sciences. 114
After fusion, HIV delivers its conical capsid into the cytoplasm. To release the contained reverse-transcribing viral genome, the capsid must disassemble in a process termed uncoating. Defining the kinetics, dynamics, and cellular location of uncoati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95126f257eb275a156c4c4be607ab68f
https://doi.org/10.1073/pnas.1706245114
https://doi.org/10.1073/pnas.1706245114