Characterization of Foxp2 functions in the mouse cortex

Autor: Medvedeva, Vera

Des mutations du gène Foxp2 constituent le premier exemple connu de cause monogénique de troubles de la parole et du langage. Les individus atteints souffrent de difficultés d’articulation (dyspraxie verbale) mais aussi de perturbations du langa

Externí odkaz: http://www.theses.fr/2015PA066118/document

Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons

Autor: Richter, Franziska, Gao, Fuying, Medvedeva, Vera, Lee, Patrick, Bove, Nicholas, Fleming, Sheila M., Michaud, Magali, Lemesre, Vincent, Patassini, Stefano, De La Rosa, Krystal, Mulligan, Caitlin K., Sioshansi, Pedrom C., Zhu, Chunni, Coppola, Giovanni, Bordet, Thierry, Pruss, Rebecca M., Chesselet, Marie-Françoise

Publikováno v: In Neurobiology of Disease September 2014 69:263-275

How Do Electric Fields Coordinate Neuronal Migration and Maturation in the Developing Cortex? How Do Electric Fields Coordinate Neuronal Migration and Maturation in the Developing Cortex?

Autor: Medvedeva, Vera P, Pierani, Alessandra

Publikováno v: Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Frontiers media, 2020, ⟨10.3389/fcell.2020.580657⟩

International audience; During development the vast majority of cells that will later compose the mature cerebral cortex undergo extensive migration to reach their final position. In addition to intrinsically distinct migratory behaviors, cells encou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b9af70018f4c1913cf4e01f5f9cdd31a
https://www.hal.inserm.fr/inserm-02973305/document

Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease

Autor: Hickey Miriam A, Zhu Chunni, Medvedeva Vera, Lerner Renata P, Patassini Stefano, Franich Nicholas R, Maiti Panchanan, Frautschy Sally A, Zeitlin Scott, Levine Michael S, Chesselet Marie-Françoise

Publikováno v: Molecular Neurodegeneration, Vol 7, Iss 1, p 12 (2012)

Abstract Backgound No disease modifying treatment currently exists for Huntington's disease (HD), a fatal neurodegenerative disorder characterized by the formation of amyloid-like aggregates of the mutated huntingtin protein. Curcumin is a naturally

Externí odkaz: https://doaj.org/article/d038d76a033042bc8079bf5e9a6a1f21

Caractérisation des fonctions du facteur de transcription Foxp2 dans le cortex murin

Autor: Medvedeva, Vera

Publikováno v: Neurons and Cognition [q-bio.NC]. Université Pierre et Marie Curie-Paris VI, 2015. English. ⟨NNT : 2015PA066118⟩

Genetic disruptions of the forkhead box transcription factor FOXP2 in humans cause a severe autosomal-dominant speech and language disorder. FOXP2 expression pattern and genomic structure are highly conserved in distant vertebrates. We hypothesized t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::4e5c3a668bea5554707e55f59a4698e2
https://theses.hal.science/tel-01192592