Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Medulloblastoma (Clinical)"'
Publikováno v:
Asian Pacific Journal of Cancer Care, Vol 8, Iss 1, Pp 43-48 (2023)
Objective: Medulloblastoma is the most common malignant pediatric brain tumor. It has a great impact on global health. Although, current treatment modalities improve patients` survival rates, survivors suffer from long term treatment related morbidit
Externí odkaz:
https://doaj.org/article/1f19a15b3bbe408c8d9efbb6e0684c0a
Autor:
Daniel Ford, Miriam Pavon-Mengual, Helen Benghiat, Vrinda Saraff, Helen Curry, Zainaba Mohamed, Andrew C. Peet, Jenny Adamski, Martin English
Publikováno v:
Neuro-Oncology
BACKGROUND Treatment of medulloblastoma has evolved substantially with more chemotherapy, risk-adapted dosing of radiotherapy (RT) and new RT techniques. We present the endocrine profile for our patients treated over a 20-year period. METHODS The cha
Autor:
Giovanna Stefania Colafati, Sabrina Rossi, Antonella Cacchione, Francesca Diomedi Camassei, Franco Locatelli, Lucia Pedace, Evelina Miele, Angela Mastronuzzi, Andrea Carai, Giuseppe Petruzzellis
Publikováno v:
Neuro-Oncology
BACKGROUND Medulloblastoma is the most frequent malignant brain tumor in children, still resulting fatal in about one third of affected patients. An accurate diagnosis is essential for correct therapeutic stratification. The DNA methylation profile (
Autor:
Fahad E Alotabi, Matija Snuderl, Mariam AlSaeed, Amal Almutairi, Ali Abdullah O Balbaid, Rasha Alaljelaify, Albandary Alowayn, Leen Abu Safieh, Musa Alharbi, Nahla Ali Mobark, Malak Abedalthagafi, Fatmah Alqubaishi, Maqsood Ahmad, Yara Bashawri, Ayman Al-Banyan, Ebtehal A. AlSolm
Publikováno v:
Neuro-Oncology
Medulloblastoma (MB) is the most common childhood malignant brain tumor. DNA methylation profiling has rapidly advanced our understanding of MB pathogenesis at the molecular level, MBs can be sub-grouped according to methylation patterns from FPPE sa
Autor:
Andreas Faldum, Denise Obrecht, Monika Warmuth-Metz, Hildegard Dohmen, Andreas von Deimling, Paul-Gerhardt Schlegel, Andrey Korshunov, Elisabeth J. Rushing, Christine Haberler, Martin Mynarek, Torsten Pietsch, Katharina Filipski, Nicolas U. Gerber, Markus J. Riemenschneider, Jens Schittenhelm, Ori Staszewski, Brigitte Bison, Martin Benesch, Klaus Pietschmann, Clemens Sommer, Olga Zheludkova, Wolfgang Brück, Holger Ottensmeier, Andrey Golanov, Matthias Meinhardt, Stefan Rutkowski, Tanvi Sharma, Christian Mawrin, Natalie Jaeger, Ulrich Schüller, Christian Hartmann, Frank Deinlein, Camelia-Maria Monoranu, Gudrun Fleischhack, Arend Koch, André O. von Bueren, Felix Sahm, Robert Kwiecien, Stefan M. Pfister, Carsten Friedrich, Marcel Kool, Michael A. Grotzer, Marina Ryzhova, Martin Sill, Katja von Hoff, Martin Hasselblatt, Rolf-Dieter Kortmann, Irene Slavc
Publikováno v:
Neuro-Oncology
OBJECTIVE To avoid craniospinal irradiation (CSI) in children younger than four years with non-metastatic medulloblastoma by chemotherapy, intraventricular methotrexate and risk-adapted local radiotherapy. PATIENTS AND METHODS Eighty-seven patients r
Autor:
Jeffrey R. Leonard, Zachary N Funk, Christopher R. Pierson, Daniel R. Boue, Micah K Harris, Margaret Shatara, Mohamed S. AbdelBaki, Jeffrey Auletta, Jonathan L. Finlay, Rolla Abu-Arja, Jeremy Jones, Diana S Osorio, Stephan R. Paul
Publikováno v:
Neuro-Oncology
BACKGROUND Wnt-MB infers an excellent prognosis, and metastatic disease is rare. However, specific treatment strategies and patterns of failure for patients with recurrent Wnt-MB are unknown. We report two cases of recurrent beta-catenin nucleopositi
Autor:
Heinz Schmidberger, Monika Warmuth-Metz, Albrecht Glück, Karolina Jablonska, Frank Meyer, Karin Dieckmann, Torsten Pietsch, Juergen Dunst, Karin S. Kapp, Rolf-Dieter Kortmann, Martin Mynarek, Nicolas U. Gerber, Felix Placzek, Dagmar Hornung, Matthias Guckenberger, Frank Heinzelmann, Volker Budach, Carmen Martini, Christoph Pöttgen, Jutta Welzel, Rudolf Schwarz, Christiane Matuschek, Katja von Hoff, Frank Paulsen, Montserrat Pazos, Klaus Pietschmann, Beate Timmermann, Robert Kwiecien, Stefan M. Pfister, Stefan Dietzsch, Sabine Klagges, Anca L. Grosu, Steven C. Clifford, Stefan Rutkowski, Martin Benesch, André O. von Bueren
Publikováno v:
Neuro-Oncology
PURPOSE To evaluate prognostic factors and impact of participation in a randomized trial in non-metastatic medulloblastoma. METHODS AND PATIENTS 382 patients with non-metastatic medulloblastoma aged 4–21 years with primary neurosurgical resections
Autor:
Nicolas André, Julien Masliah-Planchon, Cécile Faure-Conter, Rachid Abbas, Anne Geoffray, Emilie De Carli, Celine Chappe, Pierre Leblond, Anne-Isabelle Bertozzi, Gilles Palenzuela, Christine Soler, Marie-Bernadette Delisle, Fanny Fouyssac, Jacques Grill, Natacha Entz-Werle, Christelle Dufour, Claire Pluchart, Franck Bourdeaut
Publikováno v:
Neuro-Oncology
PURPOSE To assess the 3-year EFS rate of children younger than 5 years of age with high-risk medulloblastoma (MB) treated according to the prospective multicenter trial HR MB-5. PATIENTS AND METHODS After surgery, all children received 2 cycles of Et
Publikováno v:
Neuro-Oncology
BACKGROUND Metronomic and targeted anti-angiogenesis therapy (MEMMAT) has emerged as a promising treatment for recurrent/progressive medulloblastoma. This treatment includes bevacizumab, oral agents (thalidomide, celecoxib, fenofibrate, etoposide & c
Autor:
Vasily Grigorenko, Svetlana Zagidullina, Sergey Gorelyshev, Stepan Babelyan, Georgy Mentkevich, Dmitry Khochenkov, Vidmante Daylidite, Anna Stroganova, Natalya Subbotina, Dmitry Sidelnikov, Shavkat Kadirov, Marina Ryzhova, Andrey Levashov
Publikováno v:
Neuro-Oncology
The aim of this study was to identify a group of patients aged 3 to 7 years for whom there is the possibility for reducing of craniospinal radiation dose (CSI). From 2008 to 2018 fifty one pediatric patients with primary diagnosed medulloblastoma in