Výsledky vyhledávání - "Medizinische Fakultät » Universitätsklinikum Essen

CGRP antibody therapy in patients with drug resistant migraine and chronic daily headache: a real-world experience

Autor: Hannah Schenk, Christoph Kleinschnitz, Michael Nsaka, Sebastian Wurthmann, Dagny Holle, Armin Scheffler, Martin Glas

Publikováno v: The Journal of Headache and Pain, Vol 22, Iss 1, Pp 1-6 (2021)
The Journal of Headache and Pain

Background Calcitonin gene-related peptide (CGRP) (receptor) antibodies (erenumab, fremanezumab and galcanezumab) are increasingly used in prophylactic treatment of migraine. In the approval studies, severely affected patients with migraine and chron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b72687869650fe3781cee0206542845
https://doaj.org/article/b731ecb7817c491b94df4ef044ea44d5

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Fluctuation of depressive symptoms in cognitively unimpaired participants and the risk of mild cognitive impairment 5 years later: Results of the Heinz Nixdorf Recall study

Autor: Jokisch, Martha, Schramm, Sara, Weimar, Christian, Moebus, Susanne, Gronewold, Janine, Dragano, Nico, Jöckel, Karl-Heinz

Publikováno v: Frontiers in behavioral neuroscience. 16

BackgroundDepression might be an independent risk factor for cognitive decline, a prodromal dementia symptom or a reaction to cognitive/functional impairment.ObjectiveTo investigate the association between (1) depressive symptoms and (2) depressive s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb4fc76fba12b773d8e434b8f655af0
https://pubmed.ncbi.nlm.nih.gov/36386784

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Optimizing geriatric patient care via screening for risk of functional decline

Autor: Gronewold, Janine

Due to demographic changes, the German health system is confronted with an increasing number of older, multimorbid (geriatric) patients. Even though there is increasing interest in understanding the role of geriatric problems for poor health outcomes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d889e630d61e7971e81860913a53eee1
https://duepublico2.uni-due.de/receive/duepublico_mods_00075910

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Extrahepatic portosystemic shunts as an unusual but treatable cause of hyperammonemic encephalopathy in a noncirrhotic patient - a case report

Autor: Jordi Kühne Escolà, Jens M. Theysohn, Yan Li, Michael Forsting, Philipp Capetian, Jens Volkmann, Christian Lange, Carlos M. Quesada, Martin Köhrmann, Benedikt Frank, Christoph Kleinschnitz

We report a case of hyperammonemic encephalopathy due to extrahepatic portosystemic shunts in a noncirrhotic patient. A 79-year-old woman suffered from episodic confusion, disorientation, dysphasia and fluctuating level of consciousness. Electroencep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c561e502ec39564248ee4d4727aa203d
https://duepublico2.uni-due.de/receive/duepublico_mods_00076564

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Combined radiotherapy and concurrent tumor treating fields (TTFields) for glioblastoma: Dosimetric consequences on non-coplanar IMRT as initial results from a phase I trial

Publikováno v: Radiation Oncology, Vol 15, Iss 1, Pp 1-11 (2020)
Radiation Oncology (London, England)

Background Glioblastoma is a rapidly proliferating tumor. Patients bear an inferior prognosis with a median survival time of 14-16 months. Proliferation and repopulation are a major resistance promoting factor for conventionally fractionated radiothe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::308124ac2b791564c8640a5ce336b04b
http://link.springer.com/article/10.1186/s13014-020-01521-7

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Positive treatment expectations shape perceived medication efficacy in a translational placebo paradigm for the gut-brain axis

Autor: Sven Benson, Nina Theysohn, Julian Kleine-Borgmann, Laura Rebernik, Adriane Icenhour, Sigrid Elsenbruch

Placebo research has established the pivotal role of treatment expectations in shaping symptom experience and patient-reported treatment outcomes. Perceived treatment efficacy constitutes a relevant yet understudied aspect, especially in the context

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c78823f080416fd7cd220a257b1af39a
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/9056

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Assessment of Health-Related Quality of Life in Adult Spinal Muscular Atrophy Under Nusinersen Treatment—A Pilot Study

Autor: Andreas Thimm, Svenja Brakemeier, Kathrin Kizina, Juan Munoz Rosales, Benjamin Stolte, Andreas Totzeck, Cornelius Deuschl, Christoph Kleinschnitz, Tim Hagenacker

Publikováno v: Frontiers in Neurology
Frontiers in Neurology, Vol 12 (2022)

OA Förderung 2022 5q-Spinal muscular atrophy (SMA) is a severely disabling inherited neuromuscular disease that progressively reduces the motor abilities of affected individuals. The approval of the antisense oligonucleotide nusinersen, which has be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94a2a320362dbab3ce82b9d12ba231b
https://doi.org/10.3389/fneur.2021.812063

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Roles of Polymorphonuclear Neutrophils in Ischemic Brain Injury and Post-Ischemic Brain Remodeling

Autor: Ayan Mohamud Yusuf, Nina Hagemann, Peter Ludewig, Matthias Gunzer, Dirk M. Hermann

Publikováno v: Frontiers in Immunology, Vol 12 (2022)
Frontiers in Immunology

Following ischemic stroke, polymorphonuclear neutrophils (PMNs) are rapidly recruited to the ischemic brain tissue and exacerbate stroke injury by release of reactive oxygen species (ROS), proteases and proinflammatory cytokines. PMNs may aggravate p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f18e0d267c2938bd9d8a9b7676664a
https://duepublico2.uni-due.de/receive/duepublico_mods_00076409

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