Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Medium-throughput"'
Autor:
Marwah Al-Aloosi, Amanda M. Prechtl, Payel Chatterjee, Brady Bernard, Christopher J. Kemp, Rachele Rosati, Robert L. Diaz, Lauren R. Appleyard, Shalini Pereira, Alex Rajewski, Amber McDonald, Eva J. Gordon, Carla Grandori
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
Patients presenting with stage 4 ovarian carcinoma, including low-grade serous disease, have a poor prognosis. Although platinum-based therapies can offer some response, these therapies are associated with many side effects, and treatment resistance
Externí odkaz:
https://doaj.org/article/fcc76ebb292445b4b3f929be800bb6b7
Akademický článek
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Autor:
Guillaume Fouché, Dominique Rosati, Catherine Venet, Hervé Josserand, Marie-Pascale Latorse, Danièle Debieu, Sabine Fillinger
Publikováno v:
Microorganisms, Vol 10, Iss 8, p 1494 (2022)
Increased drug efflux compromises the efficacy of a large panel of treatments in the clinic against cancer or bacterial, fungal, and viral diseases, and in agriculture due to the emergence of multidrug-resistant pathogenic fungi. Until recently, to d
Externí odkaz:
https://doaj.org/article/b7004021a34545ef92f8e76b13c9e32c
Autor:
Saulo Muniz Martins, Giovani Greigh de Brito, Washington da Conceição Gonçalves, Bruna Mendes Diniz Tripode, Marc Lartaud, João Batista Duarte, Camilo de Lelis Morello, Marc Giband
Publikováno v:
Scientia Agricola, Vol 77, Iss 5 (2019)
ABSTRACT: The root system architecture (RSA) of plants and its functioning play a fundamental role in a number of plant growth mechanisms including water and nutrient uptake. Optimization of the RSA is important for stable and increased plant product
Externí odkaz:
https://doaj.org/article/1d872ca224284dcf8d117f64b5c71c07
Akademický článek
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Autor:
Arno Verlee, Thomas Heugebaert, Tom van der Meer, Pavel I. Kerchev, Frank Van Breusegem, Christian V. Stevens
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 303-312 (2017)
For the synthesis of m-sulfamoylbenzamide analogues, small molecules which are known for their bioactivity, a chemoselective procedure has been developed starting from m-(chlorosulfonyl)benzoyl chloride. Although a chemoselective process in batch was
Externí odkaz:
https://doaj.org/article/0680057355e141569b9b2c1fa11aa8df
Autor:
Santucci, M., Luciani, R., Gianquinto, E., Pozzi, C., Di Pisa, F., Dello Iacono, L., Landi, G., Tagliazucchi, L., Mangani, S., Spyrakis, F., Costi, M. P.
Publikováno v:
Pharmaceuticals, Vol 14, Iss 1246, p 1246 (2021)
Pharmaceuticals
Pharmaceuticals
Three open-source anti-kinetoplastid chemical boxes derived from a whole-cell phenotypic screening by GlaxoSmithKline (Tres Cantos Anti-Kinetoplastid Screening, TCAKS) were exploited for the discovery of a novel core structure inspiring new treatment
Autor:
Andrew M. Piggott, Samantha J. Emery-Corbin, Daniel Vuong, Aaron R. Jex, Ernest Lacey, Alexander Y.F. Lam
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 15, Iss, Pp 68-80 (2021)
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance
Trichomonas vaginalis is a neglected urogenital parasitic protist that causes 170 million cases of trichomoniasis annually, making it the most prevalent non-viral, sexually transmitted disease. Trichomoniasis treatment relies on nitroheterocyclics, s
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 9, Pp 19341-19360 (2013)
Haliotis midae is one of the most valuable commercial abalone species in the world, but is highly vulnerable, due to exploitation, habitat destruction and predation. In order to preserve wild and cultured stocks, genetic management and improvement of
Externí odkaz:
https://doaj.org/article/e0fc4e88307d46f7a615cf9fd8ebae12
Autor:
Costi, Matteo Santucci, Rosaria Luciani, Eleonora Gianquinto, Cecilia Pozzi, Flavio di Pisa, Lucia dello Iacono, Giacomo Landi, Lorenzo Tagliazucchi, Stefano Mangani, Francesca Spyrakis, Maria Paola
Publikováno v:
Pharmaceuticals; Volume 14; Issue 12; Pages: 1246
Three open-source anti-kinetoplastid chemical boxes derived from a whole-cell phenotypic screening by GlaxoSmithKline (Tres Cantos Anti-Kinetoplastid Screening, TCAKS) were exploited for the discovery of a novel core structure inspiring new treatment