Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Medini Reddy-Luthmoodoo"'
MicroRNA-194 Modulates Glucose Metabolism and Its Skeletal Muscle Expression Is Reduced in Diabetes.
Autor:
Celine Latouche, Alaina Natoli, Medini Reddy-Luthmoodoo, Sarah E Heywood, James A Armitage, Bronwyn A Kingwell
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155108 (2016)
BACKGROUND:The regulation of microRNAs (miRNAs) at different stages of the progression of type 2 diabetes mellitus (T2DM) and their role in glucose homeostasis was investigated. METHODS:Microarrays were used to assess miRNA expression in skeletal mus
Externí odkaz:
https://doaj.org/article/e0cd0411f20c4b3c93e25738eba8c2f5
Autor:
Brian G. Drew, Andrew L. Carey, Alaina K. Natoli, Melissa F. Formosa, Donna Vizi, Medini Reddy-Luthmoodoo, Jacquelyn M. Weir, Christopher K. Barlow, Gerrit van Hall, Peter J. Meikle, Stephen J. Duffy, Bronwyn A. Kingwell
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 3, Pp 572-581 (2011)
We recently demonstrated that reconstituted high-density lipoprotein (rHDL) modulates glucose metabolism in humans via both AMP-activated protein kinase (AMPK) in muscle and by increasing plasma insulin. Given the key roles of both AMPK and insulin i
Externí odkaz:
https://doaj.org/article/ce166b01cfbd4c24950c9e5b1499a216
Autor:
Andrew L Carey, Camilla Vorlander, Medini Reddy-Luthmoodoo, Alaina K Natoli, Melissa F Formosa, David A Bertovic, Mitchell J Anderson, Stephen J Duffy, Bronwyn A Kingwell
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91997 (2014)
Brown adipose tissue (BAT) is a potential therapeutic target to reverse obesity. The purpose of this study was to determine whether primary precursor cells isolated from human adult subcutaneous white adipose tissue (WAT) can be induced to differenti
Externí odkaz:
https://doaj.org/article/3bb7cdd4f2a34a4aa34cf3ad31520729
Autor:
Andrew L Carey, Andrew L Siebel, Medini Reddy-Luthmoodoo, Alaina K Natoli, Wilissa D'Souza, Peter J Meikle, Dmitri Sviridov, Brian G Drew, Bronwyn A Kingwell
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56601 (2013)
BackgroundEmerging evidence suggests that high density lipoprotein (HDL) may modulate glucose metabolism through multiple mechanisms including pancreatic insulin secretion as well as insulin-independent glucose uptake into muscle. We hypothesized tha
Externí odkaz:
https://doaj.org/article/2181b4a92372466c9d1cff4a6b159642
Autor:
David W. Dunstan, Pia Varsamis, Paddy C. Dempsey, Robyn N. Larsen, Brooke L. Devlin, Neale Cohen, Garry L. Jennings, Melissa F. Formosa, Bronwyn A. Kingwell, John A. Hawley, Megan S. Grace, Neville Owen, Medini Reddy-Luthmoodoo
Background & aims Chronic overconsumption of sugar-sweetened beverages (SSBs) is associated with unfavourable health effects, including promotion of obesity. However, the acute effects of consuming SSBs on glucose and lipid metabolism remain to be ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80ee83e4b242c24bcb8dae007b5d4d1
https://acuresearchbank.acu.edu.au/item/8v883/between-meal-sucrose-sweetened-beverage-consumption-impairs-glycaemia-and-lipid-metabolism-during-prolonged-sitting-a-randomized-controlled-trial
https://acuresearchbank.acu.edu.au/item/8v883/between-meal-sucrose-sweetened-beverage-consumption-impairs-glycaemia-and-lipid-metabolism-during-prolonged-sitting-a-randomized-controlled-trial
Autor:
Si Khiang Trinh, Gerrit van Hall, Andrew L. Carey, Piyushkumar A. Mundra, Stephen J. Duffy, Andrew L. Siebel, Bronwyn A. Kingwell, Melissa F. Formosa, Kevin Huynh, Jan Johansson, Kerry-Anne Rye, Chiara Dalla-Man, Allan Gordon, Jim D. Otvos, Alaina K. Natoli, Medini Reddy-Luthmoodoo, Dmitri Sviridov, Claudio Cobelli, Philip J. Barter, Norman C.W. Wong, Anmar A. Khan, Peter J. Meikle
Publikováno v:
Metabolism. 65:904-914
Aims High-density lipoprotein (HDL) and apolipoprotein A-I (apoA-I) can modulate glucose metabolism through multiple mechanisms. This study determined the effects of a novel bromodomain and extra-terminal (BET) inhibitor (RVX-208) and putative apoA-I
Autor:
Medini Reddy-Luthmoodoo, Alaina K. Natoli, Dmitri Sviridov, Andrew L. Siebel, Felicia Y. T. Yap, Josephine M. Forbes, Chek Ing Kiu Weber, Georgina Meneses-Lorente, Cyrille Maugeais, Andrew L. Carey, Bronwyn A. Kingwell
Publikováno v:
Circulation Research. 113:167-175
Rationale: High-density lipoprotein cholesterol elevation via cholesteryl ester transfer protein (CETP) inhibition represents a novel therapy for atherosclerosis, which also may have relevance for type 2 diabetes mellitus. Objective: The current stud
Autor:
David W. Dunstan, Alaina K. Natoli, Celine Latouche, Neville Owen, Bronwyn A. Kingwell, Audrey Bergouignan, Sarah E Heywood, Medini Reddy-Luthmoodoo, Megan S. Grace
Publikováno v:
Scientific Reports
Epidemiological studies have observed associations between frequent interruptions of sitting time with physical activity bouts and beneficial metabolic outcomes, even in individuals who regularly exercise. Frequent interruptions to prolonged sitting
Autor:
James A. Armitage, Celine Latouche, Medini Reddy-Luthmoodoo, Alaina K. Natoli, Sarah E Heywood, Bronwyn A. Kingwell
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 5, p e0155108 (2016)
PLoS ONE, Vol 11, Iss 5, p e0155108 (2016)
Background The regulation of microRNAs (miRNAs) at different stages of the progression of type 2 diabetes mellitus (T2DM) and their role in glucose homeostasis was investigated. Methods Microarrays were used to assess miRNA expression in skeletal mus
Autor:
Adele Richart, Sarah Heywood, Medini Reddy-luthmoodoo, Alaina K Natoli, Helen Kiriazis, Xiao-Jun Du, Andrew Siebel, Bronwyn Kingwell
Publikováno v:
Circulation. 132
Aims: High-density lipoprotein (HDL) has multiple actions which may benefit post-ischemic heart function. We have shown in patients with type 2 diabetes that a single infusion of reconstituted HDL (rHDL, CSL-111) reduces inflammation1 including the n