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Akademický článek

Sodium channel current loss of function in induced pluripotent stem cell-derived cardiomyocytes from a Brugada syndrome patient.

Autor: Selga E; Cardiovascular Genetics Centre, Department of Medical Sciences, University of Girona, Girona, Spain; Institut d'Investigació Biomèdica de Girona (IDIBGI), Girona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain., Sendfeld F; Scottish Centre for Regenerative Medicine, University of Edinburgh, United Kingdom; BHF/University Centre for Cardiovascular Sciences, University of Edinburgh, United Kingdom., Martinez-Moreno R; Cardiovascular Genetics Centre, Department of Medical Sciences, University of Girona, Girona, Spain; Institut d'Investigació Biomèdica de Girona (IDIBGI), Girona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain., Medine CN; Scottish Centre for Regenerative Medicine, University of Edinburgh, United Kingdom; BHF/University Centre for Cardiovascular Sciences, University of Edinburgh, United Kingdom., Tura-Ceide O; Department of Pulmonary Medicine, Hospital Clinic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, University of Barcelona, Spain., Wilmut SI; Scottish Centre for Regenerative Medicine, University of Edinburgh, United Kingdom., Pérez GJ; Cardiovascular Genetics Centre, Department of Medical Sciences, University of Girona, Girona, Spain; Institut d'Investigació Biomèdica de Girona (IDIBGI), Girona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain., Scornik FS; Cardiovascular Genetics Centre, Department of Medical Sciences, University of Girona, Girona, Spain; Institut d'Investigació Biomèdica de Girona (IDIBGI), Girona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain., Brugada R; Cardiovascular Genetics Centre, Department of Medical Sciences, University of Girona, Girona, Spain; Institut d'Investigació Biomèdica de Girona (IDIBGI), Girona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain; Hospital Josep Trueta, Girona, Spain., Mills NL; BHF/University Centre for Cardiovascular Sciences, University of Edinburgh, United Kingdom. Electronic address: nick.mills@ed.ac.uk.

Publikováno v: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2018 Jan; Vol. 114, pp. 10-19. Date of Electronic Publication: 2017 Oct 09.

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Akademický článek

Galectin-3 regulates hepatic progenitor cell expansion during liver injury.

Autor: Hsieh WC; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Mackinnon AC; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Lu WY; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Jung J; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Boulter L; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Henderson NC; MRC/Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Simpson KJ; Department of Hepatology, Edinburgh Royal Infirmary, Edinburgh, UK., Schotanus B; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Wojtacha D; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Bird TG; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Medine CN; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Hay DC; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Sethi T; Department of Respiratory Medicine and Allergy, Kings College Denmark Hill Campus, London, UK., Iredale JP; Department of Hepatology, Edinburgh Royal Infirmary, Edinburgh, UK., Forbes SJ; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.

Publikováno v: Gut [Gut] 2015 Feb; Vol. 64 (2), pp. 312-21. Date of Electronic Publication: 2014 May 16.

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Akademický článek

Developing high-fidelity hepatotoxicity models from pluripotent stem cells.

Autor: Medine CN; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Lucendo-Villarin B, Storck C, Wang F, Szkolnicka D, Khan F, Pernagallo S, Black JR, Marriage HM, Ross JA, Bradley M, Iredale JP, Flint O, Hay DC

Publikováno v: Stem cells translational medicine [Stem Cells Transl Med] 2013 Jul; Vol. 2 (7), pp. 505-9. Date of Electronic Publication: 2013 Jun 11.

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Akademický článek

SUMOylation of HNF4α regulates protein stability and hepatocyte function.

Autor: Zhou W; Medical Research Council Centre for Regenerative Medicine, University of Edinburgh, Edinburgh Bio Quarter, 5 Little France Drive, Edinburgh EH16 4UU, UK., Hannoun Z, Jaffray E, Medine CN, Black JR, Greenhough S, Zhu L, Ross JA, Forbes S, Wilmut I, Iredale JP, Hay RT, Hay DC

Publikováno v: Journal of cell science [J Cell Sci] 2012 Aug 01; Vol. 125 (Pt 15), pp. 3630-5. Date of Electronic Publication: 2012 Apr 14.

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Akademický článek

Stem cell differentiation and human liver disease.

Autor: Zhou WL; Department of Gastroenterology, Changzheng Hospital, Second Military Medical University of China, Shanghai 200003, China., Medine CN, Zhu L, Hay DC

Publikováno v: World journal of gastroenterology [World J Gastroenterol] 2012 May 07; Vol. 18 (17), pp. 2018-25.

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Akademický článek

Robust generation of hepatocyte-like cells from human embryonic stem cell populations.

Autor: Medine CN; Medical Research Council Centre for Regenerative Medicine, University of Edinburgh., Lucendo-Villarin B, Zhou W, West CC, Hay DC

Publikováno v: Journal of visualized experiments : JoVE [J Vis Exp] 2011 Oct 26 (56), pp. e2969. Date of Electronic Publication: 2011 Oct 26.

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Akademický článek

Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism.

Autor: Hay DC; MRC Centre for Regenerative Medicine, University of Edinburgh, Chancellor's Building, Edinburgh, EH16 4SB, UK. davehay@talktalk.net, Pernagallo S, Diaz-Mochon JJ, Medine CN, Greenhough S, Hannoun Z, Schrader J, Black JR, Fletcher J, Dalgetty D, Thompson AI, Newsome PN, Forbes SJ, Ross JA, Bradley M, Iredale JP

Publikováno v: Stem cell research [Stem Cell Res] 2011 Mar; Vol. 6 (2), pp. 92-102. Date of Electronic Publication: 2010 Dec 10.

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Akademický článek

Persistence of functional hepatocyte-like cells in immune-compromised mice.

Autor: Payne CM; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK. catherine.payne@ed.ac.uk, Samuel K, Pryde A, King J, Brownstein D, Schrader J, Medine CN, Forbes SJ, Iredale JP, Newsome PN, Hay DC

Publikováno v: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2011 Feb; Vol. 31 (2), pp. 254-62. Date of Electronic Publication: 2010 Dec 10.

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