Medical Gas Therapy for Tissue, Organ, and CNS Protection: A Systematic Review of Effects, Mechanisms, and Challenges

Autor: Ross D. Zafonte, Lei Wang, Christian A. Arbelaez, Rachel Dennison, Yang D. Teng

Publikováno v: Advanced Science, Vol 9, Iss 13, Pp n/a-n/a (2022)

Abstract Gaseous molecules have been increasingly explored for therapeutic development. Here, following an analytical background introduction, a systematic review of medical gas research is presented, focusing on tissue protections, mechanisms, data

Externí odkaz: https://doaj.org/article/fe0e2a8449f3488e815d4d530504f76e

High flow nasal cannula (HFNC) with Heliox decreases diaphragmatic injury in a newborn porcine lung injury model

Autor: Ann M. Hesek, Jordan V Wang, Haritha Vellanki, Marla R. Wolfson, Thomas H. Shaffer, Jichuan Wu, Elena Rodriguez, Romal K. Jassar, Yan Zhu

Publikováno v: Pediatric Pulmonology. 49:1214-1222

Summary Background High flow nasal cannula (HFNC) improves ventilation by washing out nasopharyngeal dead space while delivering oxygen. Heliox (helium–oxygen gas mixture), a low-density gas mixture, decreases resistance to airflow, reduces the wor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::23a731f0ef95feb0352959b4bc7f8a36
https://doi.org/10.1002/ppul.23000

High flow nasal heliox improves work of breathing and attenuates lung injury in a newborn porcine lung injury model

Autor: Jordan V Wang, Yan Zhu, Marla R. Wolfson, Elena Rodriguez, T.H. Shaffer, Haritha Vellanki, R.K. Jassar, Anne M. Hesek

Publikováno v: Journal of neonatal-perinatal medicine. 8(4)

Background High flow nasal cannula (HFNC) has been shown to improve ventilation and oxygenation and reduce work of breathing in newborns with respiratory distress. Heliox, decreases resistance to airflow, reduces the work of breathing, facilitates th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c6e4934d1c4bb01ec7be552e46759e
https://pubmed.ncbi.nlm.nih.gov/26757007

Combination of heliox and CPAP without a ventilator

Autor: MW Nijsten, H. J. Boersma, Willem Dieperink, Leon Aarts, J.F. Goorhuis, G. B. Eindhoven, J. A. Knol

Publikováno v: European Journal of Anaesthesiology, 24(10), 889-891. LIPPINCOTT WILLIAMS & WILKINS
European Journal of Anaesthesiology, 24(10), 889-891. Blackwell Science

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249e3bc16d63132572952c7925ea70b6
https://hdl.handle.net/11370/cc2e1c6a-2f96-43ba-afbe-b57ad2c15a8f

Mechanical ventilation with heliox in an animal model of acute respiratory distress syndrome

Autor: Hamid Aslami, Nicole P. Juffermans, Margreeth B. Vroom, Charlotte J. P. Beurskens, Friso M. de Beer, Joris J. T. H. Roelofs

Publikováno v: Intensive Care Medicine Experimental
Intensive Care Medicine Experimental, 2(1). Springer Science + Business Media

Background Heliox has a lower density and higher diffusion capacity compared to oxygen-in-air. We hypothesized that heliox ventilation allows for a reduction in minute volume ventilation and inspiratory pressures needed for adequate gas exchange in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68008f3ecd277ed2caa2b655dbdc7ce0
https://pubmed.ncbi.nlm.nih.gov/26266912