Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Medical and clinical diagnostics"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports
Scientific Reports
The worldwide emergence and spread of antimicrobial resistance is accelerated by irrational administration and use of empiric antibiotics. A key point to the crisis is a lack of rapid diagnostic protocols for antimicrobial susceptibility testing (AST
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Development of paper-based microfluidic devices that perform colorimetric measurements requires quantitative image analysis. Because the design geometries of paper-based microfluidic devices are not standardized, conventional methods for performing b
Autor:
Yuka Yajima, Norishige Yamada, Keisuke Shima, Takushi Yamamoto, Yoshiki Arakawa, Masahiro Ikegami, Yu Kakimoto, Hideshi Fujiwake, Takuya Hiratsuka, Ko-ichi Fujimoto, Tatsuaki Tsuruyama, Yuzo Yamazaki
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Imaging mass spectrometry (IMS) has been rarely used to examine specimens of human brain tumours. In the current study, high quality brain tumour samples were selected by tissue observation. Further, IMS analysis was combined with a new hierarchical
Autor:
Russell K. Pirlo, Paola Parlanti, Akos Vertes, Christine A. Brantner, Jacqueline E. Dyer, Nicholas J. Morris, Derek Jones, Jarod A. Fincher, Andrew R. Korte, Anastas Popratiloff, Victoria K. Shanmugam
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Neutral lipids have been implicated in a host of potentially debilitating human diseases, such as heart disease, type-2 diabetes, and metabolic syndrome. Matrix-assisted laser desorption ionization (MALDI), the method-of-choice for mass spectrometry
Autor:
Eleanor Sinclair, Caitlin Walton-Doyle, Perdita E. Barran, Monty Silverdale, Drupad K. Trivedi, Depanjan Sarkar, Rob M.A. de Bie, Joy Milne, Royston Goodacre, Anouk M. Rijs, Tilo Kunath
Publikováno v:
Sinclair, E, Trivedi, D K, Sarkar, D, Walton-Doyle, C, Milne, J, Kunath, T, Rijs, A M, de Bie, R M A, Goodacre, R, Silverdale, M & Barran, P 2021, ' Metabolomics of sebum reveals lipid dysregulation in Parkinson’s disease ', Nature Communications, vol. 12, no. 1, 1592 . https://doi.org/10.1038/s41467-021-21669-4
Nature Communications
Nature Communications, 12, 1-9
Nature Communications, 12, 1, pp. 1-9
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Sinclair, E, Trivedi, D K, Sarkar, D, Walton-Doyle, C, Milne, J, Kunath, T, Rijs, A M, De Bie, R M A, Goodacre, R, Silverdale, M & Barran, P 2021, ' Metabolomics of sebum reveals lipid dysregulation in Parkinson’s disease ', Nature Communications, vol. 12, no. 1, 1592 . https://doi.org/10.1038/s41467-021-21669-4
Nature communications, 12(1):1592. Nature Publishing Group
Nature Communications, 12(1):1592. Nature Publishing Group
Nature Communications
Nature Communications, 12, 1-9
Nature Communications, 12, 1, pp. 1-9
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Sinclair, E, Trivedi, D K, Sarkar, D, Walton-Doyle, C, Milne, J, Kunath, T, Rijs, A M, De Bie, R M A, Goodacre, R, Silverdale, M & Barran, P 2021, ' Metabolomics of sebum reveals lipid dysregulation in Parkinson’s disease ', Nature Communications, vol. 12, no. 1, 1592 . https://doi.org/10.1038/s41467-021-21669-4
Nature communications, 12(1):1592. Nature Publishing Group
Nature Communications, 12(1):1592. Nature Publishing Group
Parkinson’s disease (PD) is a progressive neurodegenerative disorder, which is characterised by degeneration of distinct neuronal populations, including dopaminergic neurons of the substantia nigra. Here, we use a metabolomics profiling approach to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726fbf88e6bb3535c500dff0227be3f9
https://research.vu.nl/en/publications/b064726a-c025-4f1a-949e-7d3bece06441
https://research.vu.nl/en/publications/b064726a-c025-4f1a-949e-7d3bece06441
Autor:
Anastasia Spyrogianni, Charlotte Gourmel, Leopold Hofmann, Jessica Marbach, Jean-Christophe Leroux
Publikováno v:
Scientific Reports, 11 (1)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Reliable ammonia quantification assays are essential for monitoring ammonemia in patients with liver diseases. In this study, we describe the development process of a microplate-based assay for accurate, precise, and robust ammonia quantification in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a36f600cc5e589a983458ff6f0cad80
https://hdl.handle.net/20.500.11850/515994
https://hdl.handle.net/20.500.11850/515994
Autor:
Jürgen Zanghellini, Laura Niederstaetter, Andrea Bileck, Julia Brunmair, Astrid Slany, Samuel M. Meier-Menches, Clemens Langbauer, Benjamin Neuditschko, Christopher Gerner, Lukas Janker, Max Lennart Feuerstein, Mathias Gotsmy
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Metabolic biomonitoring in humans is typically based on the sampling of blood, plasma or urine. Although established in the clinical routine, these sampling procedures are often associated with a variety of compliance issues, which are impeding time-
Autor:
Navid Assi, Kristyna Pavelicova, Vojtech Adam, Jaroslava Bezdekova, Kristyna Zemankova, Lukas Nejdl, Mirek Macka, Marketa Vaculovicova
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports. 2021, vol. 11, issue 1, p. 1-11.
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports. 2021, vol. 11, issue 1, p. 1-11.
In this work, we explored a new approach to a simple and sensitive fluorescence detection of thiols. The approach takes advantage of an in-situ formation of UV light-induced fluorescent nanoparticles (ZnCd/S quantum dots), while utilizing the thiol g
Autor:
Kamilla Malek, Katarzyna Bulat, Agnieszka Jasztal, Roman Pulyk, Jakub Dybas, Aneta Blat, Agnieszka Slowik, Tadeusz Popiela, Katarzyna M. Marzec, Magdalena Kaczmarska, Mateusz G. Adamski, Karolina Chrabaszcz
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
The significance and utility of innovative imaging techniques in arterial clot analysis, which enable far more detailed and automated analysis compared to standard methods, are presented. The examination of two types of human thrombi is shown, repres
Autor:
Tyler C. Thacker, Pauline Nol, Jacek A. Koziel, Somchai Rice, Christine K. Ellis, Kurt C. VerCauteren, Devin L. Maurer
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
The primary hurdle for diagnosis of some diseases is the long incubation required to culture and confirm the presence of bacteria. The concept of using microbial VOCs as “signature markers” could provide a faster and noninvasive diagnosis. Findin