Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mediation of Immunological Injury"'
Publikováno v:
The Journal of Experimental Medicine
Human PMN release lysosomal enzymes (beta-glucuronidase, acid phosphatase) when exposed to immune complexes, but do not release cytoplasmic LDH. The cells remain viable, and failure of LDH to appear in supernatants is not due to selective absorption
Autor:
P A, Ward
Publikováno v:
The Journal of Experimental Medicine
Leukotactic factors derived from the complement sequence consist of C5-related products, including the small cleavage product and the higher molecular weight complex (C567). A leukotactically active cleavage product (of low molecular weight) has also
Autor:
P M, Henson
Publikováno v:
The Journal of Experimental Medicine
Neutrophils are essential mediators of tissue damage in many forms of immune complex-induced injury. In vitro, they have been shown to release some of their content of injurious constituents upon reaction with immune complexes (Fig. 10). If the compl
Publikováno v:
The Journal of Experimental Medicine
The sensitization of human lung with atopic serum is both time and temperature dependent. Highly purified IgE myeloma protein is capable of blocking sensitization of human lung with atopic serum whereas myeloma proteins of the IgG subgroups are inact
Autor:
Charles G. Cochrane
Publikováno v:
The Journal of Experimental Medicine
The mechanisms reponsible for the deposition of circulating immune complexes have been analyzed. An active process appears to be responsible in both a laboratory model in guinea pigs and in acute immune complex disease (serum sickness) in rabbits. In
Autor:
Hans J. Müller-Eberhard, Otto Götze
Publikováno v:
The Journal of Experimental Medicine
Evidence has accumulated indicating the existence of a second complement activation mechanism which is functionally analogous to C1, C2, and C4. The noncomplement protein C3PA, previously recognized through its ability to form a complex enzyme with a