Zobrazeno 1 - 10
of 562
pro vyhledávání: '"Medial septal nucleus"'
Autor:
Lindsey M. Crown, Kofi A. Agyeman, Wooseong Choi, Nancy Zepeda, Ege Iseri, Pooyan Pahlavan, Steven J. Siegel, Charles Liu, Vasileios Christopoulos, Darrin J. Lee
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionDeep brain stimulation (DBS) has shown remarkable success treating neurological and psychiatric disorders including Parkinson’s disease, essential tremor, dystonia, epilepsy, and obsessive-compulsive disorder. DBS is now being explored
Externí odkaz:
https://doaj.org/article/6905f454ec924272b6e76664f3f287dd
Autor:
Nancy C. Zepeda, Lindsey M. Crown, Sasha Medvidovic, Wooseong Choi, Megha Sheth, Matthew Bergosh, Raymond Gifford, Caroline Folz, Phillip Lam, Gengxi Lu, Robert Featherstone, Charles Y. Liu, Steven J. Siegel, Darrin J. Lee
Publikováno v:
Neurobiology of Disease, Vol 170, Iss , Pp 105756- (2022)
Background: Few treatments exist for the cognitive symptoms of schizophrenia. Pharmacological agents resulting in glutamate N-methyl-d-aspartate (NMDA) receptor hypofunction, such as MK-801, mimic many of these symptoms and disrupt neural activity. R
Externí odkaz:
https://doaj.org/article/e6200743ce974ac9bef90ed8b90fb1f8
Akademický článek
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Autor:
Anton Fomenko, Darrin J. Lee, Chris McKinnon, Eun Jung Lee, Mitchell L. de Snoo, Elise Gondard, Clemens Neudorfer, Clement Hamani, Andres M. Lozano, Lorraine V. Kalia, Suneil K. Kalia
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
BackgroundMechanisms of deep brain stimulation (DBS) remain controversial, and spatiotemporal control of brain-wide circuits remains elusive. Adeno-associated viral (AAV) vectors have emerged as vehicles for spatiotemporal expression of exogenous tra
Externí odkaz:
https://doaj.org/article/b9a38a6302e54c7da1b98dd13d3a432e
Autor:
Li Han Sun, Chianfang G. Cherng, Ya Hsuan Chan, Yi Han Liao, Yu Han Huang, Ing Tiau B. Kuo, Hao Chen, Yi Chi Su, Lung Yu
Publikováno v:
Psychopharmacology. 238:2851-2865
This study was undertaken to assess the modulating effects of (1) pre-exposure to repeated social disruption and (2) group testing on writhing associated with visceral pain induced by intraperitoneal administration of acetic acid. Six consecutive day
Akademický článek
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Autor:
Yuta Madokoro, Masayuki Mizuno, Kenichi Adachi, Tomokazu Konishi, Daisuke Kato, Mitsutoshi Setou, Toyohiro Sato, Hiroyasu Akatsu, Noriyuki Matsukawa, Tomoaki Kahyo
Publikováno v:
Biochemical and Biophysical Research Communications. 542:80-86
Cholinergic neural activation from the medial septal nucleus to hippocampus plays a crucial role in episodic memory as a regulating system for glutamatergic neural activation in the hippocampus. As a candidate regulating factor for acetylcholine synt
Akademický článek
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Autor:
Kenichi Adachi, Toyohiro Sato, Yuto Uchida, Yuta Madokoro, Yuko Kondo-Takuma, Noriyuki Matsukawa, Yo Tsuda, Hideki Hida, Kengo Suzuki, Masayuki Mizuno, Cesario V. Borlongan, Hiroshi Takase
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
The cholinergic efferent network from the medial septal nucleus to the hippocampus plays an important role in learning and memory processes. This cholinergic projection can generate theta oscillations in the hippocampus to encode novel information. H
Autor:
P. Pasbakhsh, M. Mehdizadeh N. Omidi
Publikováno v:
Acta Medica Iranica, Vol 43, Iss 3, Pp 161-168 (2005)
Alzheimer’s disease (AD) is a uniquely human disorder. Although the pathogenesis of AD is not fully understood, growing evidence indicates that the deposition of beta-amyloid (Aβ) and the local reactions of various cell types to this protein play
Externí odkaz:
https://doaj.org/article/7847427a7eb74773b3895df4100b78c3