Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Medha Manchekar"'
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 8, Pp 2253-2264 (2010)
Microsomal triglyceride transfer protein (MTP) is required for the assembly and secretion of apolipoprotein (apo) B-containing lipoproteins. Previously, we demonstrated that the N-terminal 1,000 residues of apoB (apoB:1000) are necessary for the init
Externí odkaz:
https://doaj.org/article/5f444168f454413b97987694a56a4c49
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 10, Pp 1919-1928 (2004)
Class A peptides inhibit atherosclerosis and protect cells from class L peptide-mediated lysis. Because the cytolytic process is concentration dependent, we hypothesized that at certain concentrations both classes of peptides exert similar effect(s)
Externí odkaz:
https://doaj.org/article/ef6502b3689f43c98f95731f47733361
Publikováno v:
Biochemistry. 56:4084-4094
Our previous studies demonstrated that the first 1000 amino acid residues (the βα1 domain) of human apolipoprotein (apo) B-100, termed apoB:1000, are required for the initiation of lipoprotein assembly and the formation of a monodisperse stable pho
Autor:
Ling Li, Lei Zhang, Gang Ren, Mayakonda N. Palgunachari, Robin Zhang, Medha Manchekar, Jack F. Oram, Geeta Datta, Martin K. Jones, Andrea Catte, James C. Patterson, Jere P. Segrest
Publikováno v:
Structure (London, England : 1993), vol 23, iss 7
Summary Biogenesis of high-density lipoproteins (HDL) is coupled to the transmembrane protein, ATP-binding cassette transporter A1 (ABCA1), which transports phospholipid (PL) from the inner to the outer membrane monolayer. Using a combination of comp
Publikováno v:
Journal of Biological Chemistry. 290:8196-8205
In this study, we tested the hypothesis that phospholipid transfer protein (PLTP) is a plausible mediator of phospholipid (PL) transfer to the N-terminal 1000 residues of apoB (apoB:1000) leading to the initiation of apoB-containing lipoprotein assem
Publikováno v:
Biochemistry. 56(31)
Our previous studies demonstrated that the first 1000 amino acid residues (the βα
Publikováno v:
Plant Science. 177:629-635
The structure of the mitochondrial genome in plants is unclear, but appears to consist of mostly linear DNA with some other structures, including branched molecules and subgenomic circles. Mitochondrial DNA (mtDNA) recombination was analyzed in Brass
Publikováno v:
Journal of Biological Chemistry. 282:28597-28608
We previously demonstrated that the N-terminal 1000 amino acid residues of human apolipoprotein (apo) B (designated apoB:1000) are competent to fold into a three-sided lipovitellin-like lipid binding cavity to form the apoB "lipid pocket" without a s
Autor:
Stephanie L. McLean, Fayaz Khazi, Brent L. Nielsen, Medha Manchekar, Daqing Song, Karyn D. Scissum-Gunn
Publikováno v:
Journal of Molecular Biology. 356:288-299
Mitochondrial genomes in higher plants are much larger and more complex as compared to animal mitochondrial genomes. There is growing evidence that plant mitochondrial genomes exist predominantly as a collection of linear and highly branched DNA mole
Autor:
Anne P. Beigneux, Stephen G. Young, Paul E. Richardson, Jere P. Segrest, Medha Manchekar, Stephen C. Harvey, Nassrin Dashti, Martin K. Jones
Publikováno v:
Biophysical Journal. 88(4):2789-2800
Apolipoprotein B (apoB) is the major protein component of large lipoprotein particles that transport lipids and cholesterol. We have developed a detailed model of the first 1000 residues of apoB using standard sequence alignment programs (ClustalW an