Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Medha Majety"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Age is one of the strongest risk factors for severe illness from COVID-19. By integrating human lung transcriptomes with experimental data on SARS-CoV-2, the authors pinpoint specific age-associated factors that could contribute to the heightened sev
Externí odkaz:
https://doaj.org/article/1ac48135f6d342e19f2405cc2d35983e
Checkpoint blockade immunotherapy is a potent class of cancer treatment, however, the complex immunosuppressive tumor microenvironment (TME) often requires multi-agent combinations to be effective. Current cancer immunotherapy combination approaches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18cf0127999c5b7743d0cfa497d8cf7d
https://doi.org/10.1101/2023.03.14.532668
https://doi.org/10.1101/2023.03.14.532668
Autor:
Xiaoyu Zhou, Hanbing Cao, Shao-Yu Fang, Ryan D. Chow, Kaiyuan Tang, Medha Majety, Meizhu Bai, Matthew B. Dong, Paul A. Renauer, Xingbo Shang, Kazushi Suzuki, Andre Levchenko, Sidi Chen
Publikováno v:
bioRxiv
Chimeric antigen receptor (CAR) T cells are powerful therapeutics; however, their efficacy is often hindered by critical hurdles. Here, utilizing the endocytic feature of the cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) cytoplasmic tail (CT),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a627827c905a439c5b5dc10f561098f
https://europepmc.org/articles/PMC10055096/
https://europepmc.org/articles/PMC10055096/
Autor:
Matthew B. Dong, Kaiyuan Tang, Xiaoyu Zhou, Johanna Shen, Krista Chen, Hyunu R. Kim, Jerry Zhou, Hanbing Cao, Erica Vandenbulcke, Yueqi Zhang, Ryan D. Chow, Andrew Du, Kazushi Suzuki, Shao-Yu Fang, Medha Majety, Xiaoyun Dai, Sidi Chen
Publikováno v:
bioRxiv
SummaryCas9 transgenic animals have drastically accelerated the discovery of novel immune modulators. But due to its inability to process its own CRISPR RNAs (crRNAs), simultaneous multiplexed gene perturbations using Cas9 remains limited, especially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2f3c9fe5579ba654d0138ae9da2021
https://doi.org/10.1101/2023.03.14.532657
https://doi.org/10.1101/2023.03.14.532657
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Age is a major risk factor for severe coronavirus disease-2019 (COVID-19). Here, we interrogate the transcriptional features and cellular landscape of the aging human lung. By intersecting these age-associated changes with experimental data on SARS-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218807afab9a13e1e55de7348d400413
https://doi.org/10.1038/s41467-020-20323-9
https://doi.org/10.1038/s41467-020-20323-9