Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Medha D. Joshi"'
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1582 (2023)
Vancomycin is a commonly used antibiotic in hospital settings, especially against Methicillin-resistant staphylococcus aureus (MRSA). One of the major adverse events of vancomycin use in adults is kidney injury. The drug concentration, specifically t
Externí odkaz:
https://doaj.org/article/30e51b7823084c5f86cc6a27a5e8dbef
Autor:
Nicole Papp, Jeffin Panicker, John Rubino, Gwendolyn Pais, Alexander Czechowicz, Walter C. Prozialeck, Brooke Griffin, Volkmar Weissig, Marc Scheetz, Medha D. Joshi
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1153 (2022)
Drugs can be toxic to the fetus depending on the amount that permeates across the maternal–fetal barrier. One way to limit the amount which penetrates this barrier is to increase the molecular size of the drug. In this study, we have achieved this
Externí odkaz:
https://doaj.org/article/6d45d5fe8db8496691c2d1ea3e1c0e05
Publikováno v:
mSphere, Vol 4, Iss 1 (2019)
ABSTRACT This study sought to define the transit of cefepime between plasma and cerebral spinal fluid (CSF) in a rat model. Male Sprague-Dawley rats received cefepime intravenously. A total daily dose of 150 mg/kg of body weight/day was administered
Externí odkaz:
https://doaj.org/article/e369e04b7fa54d42997725c197c9cb6e
Autor:
Sean N. Avedissian, Michelle Pham, Medha D. Joshi, Marc H. Scheetz, Ashkan Salamatipour, Jeffin M. Panickar, Khrystyna Hlukhenka, Cristina Miglis, Athanasios Chalkias, Theodoros Xanthos
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 539 (2021)
While the antiarrhythmic drug amiodarone is commonly used in clinical practice, it has a narrow therapeutic index that can lead to acute overdose. One proposed method to deal with this toxicity is lipid emulsion therapy, which may potentially quench
Externí odkaz:
https://doaj.org/article/7b5602c0c2e54d4982f432961768f75d
Publikováno v:
Vaccines, Vol 2, Iss 3, Pp 515-536 (2014)
Conventional vaccine strategies have been highly efficacious for several decades in reducing mortality and morbidity due to infectious diseases. The bane of conventional vaccines, such as those that include whole organisms or large proteins, appear t
Externí odkaz:
https://doaj.org/article/68a7306141a746ef87410fd3fb6953ec
Autor:
Medha D, Joshi, Eytan A, Klausner
Publikováno v:
Currents in Pharmacy Teaching and Learning. 14:526-535
Pharmaceutical calculations is a fundamental course taken by doctor of pharmacy students in United States schools and colleges of pharmacy. To minimize medical errors and increase the accuracy with which future pharmacists perform calculations, a com
Autor:
Sean N. Avedissian, Gwendolyn M. Pais, Michelle Pham, Jiajun Liu, Jack Chang, Khrystyna Hlukhenka, Walter Prozialeck, Brooke Griffin, Anil Gulati, Medha D. Joshi, Ying Mu, Marc H. Scheetz
Publikováno v:
Antimicrob Agents Chemother
Vancomycin usage is often unavoidable in pregnant patients; however, literature suggests vancomycin can cross the placental barrier and reach the fetus. Understanding the mass transit of vancomycin to the fetus is important in pregnancy. We aimed to
Autor:
Theodoros Xanthos, Ashkan Salamatipour, Medha D. Joshi, Marc H. Scheetz, Khrystyna Hlukhenka, Michelle Pham, Jeffin M. Panickar, Athanasios Chalkias, Cristina Miglis, Sean N. Avedissian
Publikováno v:
Pharmaceutics, Vol 13, Iss 539, p 539 (2021)
Pharmaceutics
Volume 13
Issue 4
Pharmaceutics
Volume 13
Issue 4
While the antiarrhythmic drug amiodarone is commonly used in clinical practice, it has a narrow therapeutic index that can lead to acute overdose. One proposed method to deal with this toxicity is lipid emulsion therapy, which may potentially quench
Autor:
Nathaniel J. Rhodes, Anil Gulati, Thomas P. Lodise, Sean N. Avedissian, Medha D. Joshi, J. Nicholas O'Donnell, Gwendolyn M Pais, Walter C. Prozialeck, Brooke Griffin, Cristina Miglis, Marc H. Scheetz, Jiajun Liu, Lejla Catovic, Cameron Cluff
Publikováno v:
International Journal of Antimicrobial Agents. 51:239-243
Background Although the exposure-dependent efficacy thresholds of vancomycin have been probed, less is known about acute kidney injury (AKI) thresholds for this drug. Sensitive urinary biomarkers, such as kidney injury molecule 1 (KIM-1), have shown
Publikováno v:
Journal of Pharmaceutical Sciences and Pharmacology. 3:146-154