Zobrazeno 1 - 10
of 1 992
pro vyhledávání: '"Mechanisms of Signal Transduction"'
Publikováno v:
PLoS Genetics, Vol 17, Iss 12, p e1009955 (2021)
PLoS Genetics
PLoS Genetics
Histone acetylation is involved in the regulation of seed germination. The transcription factor ABI5 plays an essential role in ABA- inhibited seed germination. However, the molecular mechanism of how ABI5 and histone acetylation coordinate to regula
Autor:
Eric Blanc, Joern Toedling, Tommaso Mari, Angelika Eggert, Mathurin Dorel, Anja Sieber, Michal Nadler-Holly, Matthias Selbach, F Hertwig, Matthias Ziehm, Clemens Messerschmidt, Nils Blüthgen, Johannes H. Schulte, Bertram Klinger, Dieter Beule
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 11 (2021)
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 11, p e1009515 (2021)
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 11, p e1009515 (2021)
Very high risk neuroblastoma is characterised by increased MAPK signalling, and targeting MAPK signalling is a promising therapeutic strategy. We used a deeply characterised panel of neuroblastoma cell lines and found that the sensitivity to MEK inhi
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 12, p e1009644 (2021)
PLoS Computational Biology, Vol 17, Iss 12, p e1009644 (2021)
Peristalsis, the coordinated contraction—relaxation of the muscles of the stomach is important for normal gastric motility and is impaired in motility disorders. Coordinated electrical depolarizations that originate and propagate within a network o
Autor:
Simon Alamos, Donald Hansen, Hernan G. Garcia, Elizabeth Eck, Jonathan Liu, Yang Joon Kim, Meghan A Turner
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 5, p e1008999 (2021)
PLoS Computational Biology
PLoS Computational Biology
The eukaryotic transcription cycle consists of three main steps: initiation, elongation, and cleavage of the nascent RNA transcript. Although each of these steps can be regulated as well as coupled with each other, their in vivo dissection has remain
Autor:
Gary Struhl, Myriam Zecca
Publikováno v:
PLoS Biology, Vol 19, Iss 3, p e3001111 (2021)
PLoS Biology
PLoS Biology
Development of the Drosophila wing—a paradigm of organ development—is governed by 2 morphogens, Decapentaplegic (Dpp, a BMP) and Wingless (Wg, a Wnt). Both proteins are produced by defined subpopulations of cells and spread outwards, forming grad
Autor:
Amin Cheikhi, Cecelia C. Yates, Dana R. Julian, Carol Feghali-Bostwick, Zariel I. Johnson, Yvette P. Conley, James Lyons-Weiler, Sarah E Wheeler
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 10, p e0240986 (2020)
PLoS ONE, Vol 15, Iss 10, p e0240986 (2020)
Fibrosis is a chronic disease with heterogeneous clinical presentation, rate of progression, and occurrence of comorbidities. Systemic sclerosis (scleroderma, SSc) is a rare rheumatic autoimmune disease that encompasses several aspects of fibrosis, i
Autor:
Sharad Mistry, Kenneth W. Young, Adrian J. Butcher, Ignacio Torrecilla, Andrew R. Bottrill, Kok Choi Kong, Andrew B. Tobin
Publikováno v:
The Journal of Biological Chemistry
Changes in synaptic strength mediated by ionotropic glutamate N-methyl-D-asparate (NMDA) receptors is generally considered to be the molecular mechanism underlying memory and learning. NMDA receptors themselves are subject to regulation through signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe82464d72f3e2eb305e676e95c34dcc
Autor:
Marieke Wichers, Genetic Risk, Ulrich Reininghaus, Johanna T. W. Wigman, UnYoung Chavez-Baldini
Publikováno v:
PLoS ONE, 15(3):e0230102. PUBLIC LIBRARY SCIENCE
PLOS ONE, 15(3):0230102. Public Library of Science
PLoS ONE, Vol 15, Iss 3, p e0230102 (2020)
PLoS ONE
PLOS ONE, 15(3):0230102. Public Library of Science
PLoS ONE, Vol 15, Iss 3, p e0230102 (2020)
PLoS ONE
As emotion regulation deficits have been implicated in psychotic disorders, it is imperative to investigate not only the effect of regulation strategies but also how they are used. One such strategy is expressive suppression, the inhibition of emotio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1295c2e0222aa40a60efa9ddd140b5b7
https://research.rug.nl/en/publications/24dc2c99-ef8e-4c34-b660-68b75a9d898a
https://research.rug.nl/en/publications/24dc2c99-ef8e-4c34-b660-68b75a9d898a
Publikováno v:
PLoS ONE
The goal of cancer chemotherapy to induce multi-directional apoptosis as targeting a single pathway is unable to decrease all the downstream effect arises from crosstalk. Present study reports that Withanolide D (WithaD), a steroidal lactone isolated
Autor:
Peter Ruoff, Nobuaki Nishiyama
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0227786 (2020)
PLoS ONE
PLOS ONE
PLoS ONE
PLOS ONE
金沢大学国際基幹教育院
Homeostasis is an essential concept to understand the stability of organisms and their adaptive behaviors when coping with external and internal assaults. Many hormones that take part in homeostatic control come
Homeostasis is an essential concept to understand the stability of organisms and their adaptive behaviors when coping with external and internal assaults. Many hormones that take part in homeostatic control come
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c813b32ff4caf3f5ac93f671a75536b0
https://doi.org/10.1101/2019.12.31.891622
https://doi.org/10.1101/2019.12.31.891622