The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrity

Autor: Anna Barile, Fabrizio Barbetti, Martino L. di Salvo, Isabella Saggio, Arianna Massimi, Chiara Merigliano, Noemi Amoroso, Roberto Contestabile, Fiammetta Vernì, Lorenzo Stufera Mecarelli, Angela Tramonti, Torben Hansen, Elisa Mascolo

Publikováno v: Scientific reports (Nature Publishing Group) 9 (2019). doi:10.1038/s41598-019-50673-4
info:cnr-pdr/source/autori:Mascolo, Elisa; Barile, Anna; Mecarelli, Lorenzo Stufera; Amoroso, Noemi; Merigliano, Chiara; Massimi, Arianna; Saggio, Isabella; Hansen, Torben; Tramonti, Angela; Di Salvo, Martino Luigi; Barbetti, Fabrizio; Contestabile, Roberto; Verni, Fiammetta/titolo:The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrity/doi:10.1038%2Fs41598-019-50673-4/rivista:Scientific reports (Nature Publishing Group)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Mascolo, E, Barile, A, Mecarelli, L S, Amoroso, N, Merigliano, C, Massimi, A, Saggio, I, Hansen, T, Tramonti, A, Di Salvo, M L, Barbetti, F, Contestabile, R & Verni, F 2019, ' The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrity ', Scientific Reports, vol. 9 . https://doi.org/10.1038/s41598-019-50673-4
Scientific Reports

In eukaryotes, pyridoxal kinase (PDXK) acts in vitamin B6salvage pathway to produce pyridoxal 5′-phosphate (PLP), the active form of the vitamin, which is implicated in numerous crucial metabolic reactions. In Drosophila, mutations in the dPdxk gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f66d13f40663ee1e60bdedc4aeb4088
https://doi.org/10.1038/s41598-019-50673-4