Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mebratu A. Bitew"'
Autor:
Mebratu A. Bitew, Pablo S. Gaete, Christopher Swale, Parag Maru, Jorge E. Contreras, Jeroen P. J. Saeij
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Toxoplasma gondii, a medically important intracellular parasite, uses GRA proteins secreted from dense granule organelles to mediate nutrient flux across the parasitophorous vacuole membrane (PVM). GRA17 and GRA23 are known pore-forming prot
Externí odkaz:
https://doaj.org/article/a9e7c683dca44926a28c7b2713c37571
Autor:
Shruthi Krishnamurthy, Parag Maru, Yifan Wang, Mebratu A. Bitew, Debanjan Mukhopadhyay, Yoshiki Yamaryo-Botté, Tatiana C. Paredes-Santos, Lamba O. Sangaré, Christopher Swale, Cyrille Y. Botté, Jeroen P. J. Saeij
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Toxoplasma virulence depends on its ability to evade or survive the toxoplasmacidal mechanisms induced by interferon gamma (IFNγ). While many Toxoplasma genes involved in the evasion of the murine IFNγ response have been identified, genes
Externí odkaz:
https://doaj.org/article/aa0b609ab8e24e4ba3325ba254cf6795
Autor:
Janine Hofmann, Mebratu A Bitew, Miku Kuba, David P De Souza, Hayley J Newton, Fiona M Sansom
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255925 (2021)
The zoonotic pathogen Coxiella burnetii, the causative agent of the human disease Q fever, is an ever-present danger to global public health. Investigating novel metabolic pathways necessary for C. burnetii to replicate within its unusual intracellul
Externí odkaz:
https://doaj.org/article/59adb9cd552d42529f646706aa8879d9
Autor:
Hayley J. Newton, Miku Kuba, Fiona M. Sansom, Janine Hofmann, David P De Souza, Mebratu A Bitew
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255925 (2021)
PLoS ONE
PLoS ONE
The zoonotic pathogen Coxiella burnetii, the causative agent of the human disease Q fever, is an ever-present danger to global public health. Investigating novel metabolic pathways necessary for C. burnetii to replicate within its unusual intracellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7fcc6503f726abf04ab46f821f0dc8f
https://doi.org/10.1371/journal.pone.0255925
https://doi.org/10.1371/journal.pone.0255925
Publikováno v:
Pathogens and disease. 77(8)
The zoonotic disease Q fever caused by the intracellular bacterium Coxiella burnetii remains a global health threat due to its high infectivity, environmental stability, the debilitating nature and the long duration of treatment. Designing new and po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8804286df0a26eb471b5acacb681d758
https://pubmed.ncbi.nlm.nih.gov/31845968
https://pubmed.ncbi.nlm.nih.gov/31845968
Autor:
Nadeeka K. Wawegama, Mebratu A Bitew, Hayley J. Newton, David P De Souza, Janine Hofmann, Fiona M. Sansom
Publikováno v:
Cellular microbiologyREFERENCES. 22(5)
Coxiella burnetii, the causative agent of the zoonotic disease Q fever, is a Gram-negative bacterium that replicates inside macrophages within a highly oxidative vacuole. Screening of a transposon mutant library suggested that sdrA, which encodes a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065eb343a2fe5186dfef24cca2f78c64
https://pubmed.ncbi.nlm.nih.gov/31872956
https://pubmed.ncbi.nlm.nih.gov/31872956
Autor:
Dedreia Tull, Hayley J. Newton, David P De Souza, Nadeeka K. Wawegama, Mebratu A Bitew, Chen Ai Khoo, Nitika Neha, Fiona M. Sansom
Coxiella burnetii is an intracellular Gram-negative bacterium responsible for the important zoonotic disease Q fever. Improved genetic tools and the ability to grow this bacterium in host cell–free media has advanced the study of C. burnetii pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c4245089f122fa812cd88106a2667d
https://europepmc.org/articles/PMC6290155/
https://europepmc.org/articles/PMC6290155/
Autor:
Tatiana C Paredes-Santos, Mebratu A Bitew, Christopher Swale, Felipe Rodriguez, Shruthi Krishnamurthy, Yifan Wang, Parag Maru, Lamba Omar Sangaré, Jeroen P J Saeij
Publikováno v:
PLoS Pathogens, Vol 19, Iss 7, p e1011543 (2023)
Toxoplasma gondii is a parasite that replicates within a specialized compartment called the parasitophorous vacuole (PV), which is surrounded by the PV membrane (PVM). To obtain essential nutrients, Toxoplasma must transport molecules across the PVM,
Externí odkaz:
https://doaj.org/article/7763f771c336474c8ad688a4b1eebc12