Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Meaghan Stolk"'
Autor:
Falk Diedrichs, Meaghan Stolk, Karsten Jürchott, Marion Haag, Michael Sittinger, Martina Seifert
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Rising numbers of patients with cardiovascular diseases and limited availability of donor hearts require new and improved therapy strategies. Human atrial appendage-derived cells (hAACs) are promising candidates for an allogeneic cell-based treatment
Externí odkaz:
https://doaj.org/article/ff6cab4d59bd4f22874a0f0e9b23e4ee
Autor:
Stefan Stich, Meaghan Stolk, Pierre Pascal Girod, Claudius Thomé, Michael Sittinger, Jochen Ringe, Martina Seifert, Aldemar Andres Hegewald
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126954 (2015)
Cell-based regenerative approaches have been suggested as primary or adjuvant procedures for the treatment of degenerated intervertebral disc (IVD) diseases. Our aim was to evaluate the regenerative and immunogenic properties of mildly and severely d
Externí odkaz:
https://doaj.org/article/34fc0ea14dc247fa8e188317ed831bb6
Autor:
Aysha Schmock, Franka Klatte-Schulz, Susann Minkwitz, Britt Wildemann, Martina Seifert, Meaghan Stolk
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Inflammation plays an important role in the development and resolution of tendon diseases, but underlying mechanisms are poorly understood. We therefore aimed to analyze the response of human tenocytes to inflammatory stimuli and to uncover their int
Autor:
Naima Souidi, Katharina Schallmoser, Meaghan Stolk, Hans-Dieter Volk, Juliane Rudeck, Martina Seifert, Dirk Strunk
Publikováno v:
STEM CELLS
Regeneration of injured tissues requires effective therapeutic strategies supporting vasculogenesis. The lack of instantly available autologous cell sources and immunogenicity of allogeneic endothelial (progenitor) cells limits clinical progress. Bas
Autor:
Gabriela Korus, Annika Lubitz, Georg N. Duda, Grit Kasper, Uwe Marx, Meaghan Stolk, Jeanne Trommer, Christoph Giese, Kerstin Lehmann, Martina Seifert, Hans-Dieter Volk, Darja Könnig
Publikováno v:
The International Journal of Artificial Organs. 35:986-995
Mesenchymal stromal cells (MSC), known for their high immune modulatory capacity are promising tools for several cell-based therapies. To better mimic the in vivo situation of MSC interactions with immune cells, we applied an artificial lymph node (A
Autor:
Maria Schneider, Martina Seifert, Meaghan Stolk, Anna Biermann, I. Werner, Katrin Sudrow, Benjamin A. Högerle, Naima Souidi, Ulrich A. Stock, Kelvin G. M. Brockbank
Publikováno v:
Journal of tissue engineering and regenerative medicine. 12(2)
It has been shown previously that cryopreservation, using an ice-free cryopreservation method with the cryoprotectant formulation VS83, beneficially modulated immune reactions in vivo and in vitro when compared with conventionally frozen tissues. In
Autor:
Meaghan Stolk, Sophie Van Linthout, Carsten Tschöpe, Martina Seifert, Jochen Ringe, Michael Sittinger, Marion Haag
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 7:362-370
Cardiac-directed cell therapies show potential to reduce mortality and morbidity in heart disease. However, high functional efficacy should be complimented with low immunogenicity, in particular if allogeneic cell sources are applied. Therefore, we a
Autor:
Yoshiaki Hara, Tilo Dehne, Katja Kotsch, Petra Reinke, Martina Seifert, Meaghan Stolk, Hans-Dieter Volk, Jochen Ringe, Juliane Ladhoff, Anja Reutzel-Selke
Publikováno v:
Transplant International. 24:1112-1123
Brain death and prolonged cold ischemia are major contributors to the poorer long-term outcome of transplants from deceased donor kidney transplants, with an even higher impact if expanded criteria donors ('marginal organs') are used. Targeting ische
Autor:
Meaghan, Stolk, Martina, Seifert
Publikováno v:
Journal of Stem Cells & Regenerative Medicine
Extracellular vesicles (EV) awakened interest in the research on mesenchymal stromal cells by exploring their paracrine effects. However, many isolation protocols use bovine serum albumin (BSA) during the preparation of the EV. Therefore, we produced
Publikováno v:
Biochemical Journal. 386:281-289
Two subtypes of equilibrative transporters, es (equilibrative inhibitor-sensitive) and ei (equilibrative inhibitor-insensitive), are responsible for the majority of nucleoside flux across mammalian cell membranes. Sequence analyses of the representat