Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Meaghan Roy-O'Reilly"'
Publikováno v:
npj Microgravity, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract During spaceflight, the central nervous system (CNS) is exposed to a complex array of environmental stressors. However, the effects of long-duration spaceflight on the CNS and the resulting impact to crew health and operational performance r
Externí odkaz:
https://doaj.org/article/4941a94120884486bcb5bd3a7de0b330
Autor:
Rodney M. Ritzel, Abdullah Al Mamun, Joshua Crapser, Rajkumar Verma, Anita R. Patel, Brittany E. Knight, Nia Harris, Nickolas Mancini, Meaghan Roy-O’Reilly, Bhanu Priya Ganesh, Fudong Liu, Louise D. McCullough
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-16 (2019)
Abstract Background Ischemic stroke results in a robust inflammatory response within the central nervous system. As the immune-inhibitory CD200-CD200 receptor 1 (CD200R1) signaling axis is a known regulator of immune homeostasis, we hypothesized that
Externí odkaz:
https://doaj.org/article/bd41130a382a4de5a03d5632a95c4100
Autor:
Xiurong Zhao, Shun-Ming Ting, Chin-Hsuan Liu, Guanghua Sun, Marian Kruzel, Meaghan Roy-O’Reilly, Jaroslaw Aronowski
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Neutrophils are important modulators of tissue damage after intracerebral hemorrhage (ICH), but how this function is regulated is not clear. Here, the authors show interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least p
Externí odkaz:
https://doaj.org/article/ed8ca05aea3a4250bce07510d1521b54
Autor:
Hilda Ahnstedt, Meaghan Roy-O’Reilly, Monica S. Spychala, Alexis S. Mobley, Javiera Bravo-Alegria, Anjali Chauhan, Jaroslaw Aronowski, Sean P. Marrelli, Louise D. McCullough
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The prevalence of cardiovascular disease has increased among middle-aged women in the United States, yet has declined in middle-aged men. In experimental stroke, middle-aged females have larger strokes and greater inflammation than age-matched males
Externí odkaz:
https://doaj.org/article/d24e7fb6e256473dbd5288f5deab5aef
Autor:
Meaghan Roy-O’Reilly, Arghavan Salles
Publikováno v:
JAMA Network Open. 6:e2312131
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b629ae9e0e71243a718c3e357579dba
https://doi.org/10.1001/jamanetworkopen.2023.12131
https://doi.org/10.1001/jamanetworkopen.2023.12131
Publikováno v:
npj Microgravity, Vol 7, Iss 1, Pp 1-9 (2021)
NPJ Microgravity
NPJ Microgravity
During spaceflight, the central nervous system (CNS) is exposed to a complex array of environmental stressors. However, the effects of long-duration spaceflight on the CNS and the resulting impact to crew health and operational performance remain lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb64193631263fde3285e2b82198a47
https://doaj.org/article/4941a94120884486bcb5bd3a7de0b330
https://doaj.org/article/4941a94120884486bcb5bd3a7de0b330
Autor:
John d'Aigle, Monica S. Spychala, Liang Zhu, Anjali Chauhan, Joseph W Furr, Meaghan Roy-O'Reilly, Louise D. McCullough, Javiera Bravo Alegria, Anthony Patrizz, Frank W Blixt, Hilda Ahnstedt
Publikováno v:
Brain Behav Immun
INTRODUCTION: Stroke is a sexually dimorphic disease. While women account for more stroke deaths, recent data show that after adjusting for age and pre-stroke functional status, mortality is higher in men. Immune responses are key determinants of str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24aef39f6d556c61e062a4a405a10af
https://doi.org/10.1016/j.bbi.2020.02.001
https://doi.org/10.1016/j.bbi.2020.02.001
Autor:
Fudong Liu, Rodney M. Ritzel, Yun-Ju Lai, Jun Li, Julia Kofler, Rajkumar Verma, Meaghan Roy-O'Reilly, Sami Tarabishy, Sarah J. Doran, Louise D. McCullough, Anjali Chauhan, Ilene Staff, Hilda Ahnstedt, Anthony Patrizz, Anita R. Patel, Gillian Weston
Publikováno v:
Aging (Albany NY)
Background: Ischemic stroke is a devastating disease, often resulting in death or permanent neurological deficits. EMMPRIN/CD147 is a plasma membrane protein that induces the production of matrix metalloproteinases (MMPs), which contribute to seconda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbcb0aa44d076f829b8afac54230698c
https://doi.org/10.18632/aging.102935
https://doi.org/10.18632/aging.102935
Autor:
Monica S. Spychala, Hilda Ahnstedt, Louise D. McCullough, Jaroslaw Aronowski, Meaghan Roy-O'Reilly, Lauren H Sansing, Yashasvee Munshi
Publikováno v:
Aging (Albany NY)
Ischemic stroke is major cause of disability and mortality worldwide, and aging is strong risk factor for poor post-stroke outcome. Neutrophils traffic rapidly to the brain following ischemic stroke, and recent evidence has suggested that aging may a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935c2ef8a5c77540964970c997a31c7e
https://doi.org/10.18632/aging.102632
https://doi.org/10.18632/aging.102632
Exogenous inter-α inhibitor proteins prevent cell death and improve ischemic stroke outcomes in mice
Autor:
Anjali Chauhan, Yow-Pin Lim, Juneyoung Lee, Barbara S. Stonestreet, Liang Zhu, Anthony Patrizz, Louise D. McCullough, Venugopal Reddy Venna, Meaghan Roy-O'Reilly, Aleah Holmes, Daniel C. Kraushaar, Julia Kofler, Yun-Ju Lai, Yan Xu, Lauren H Sansing
Publikováno v:
J Clin Invest
Inter-α inhibitor proteins (IAIPs) are a family of endogenous plasma and extracellular matrix molecules. IAIPs suppress proinflammatory cytokines, limit excess complement activation, and bind extracellular histones to form IAIP-histone complexes, le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc01421b35dc9aeead0526ea6a95adc1
https://doi.org/10.1172/jci144898
https://doi.org/10.1172/jci144898