Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Meaghan A. O'Reilly"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Extensive studies on focused ultrasound (FUS)-mediated drug delivery through the blood–brain barrier have been published, yet little work has been published on FUS-mediated drug delivery through the blood-spinal cord barrier (BSCB). This w
Externí odkaz:
https://doaj.org/article/2e895380f8794339bed8f7db51fecfac
Publikováno v:
Sensors, Vol 23, Iss 3, p 1369 (2023)
The real-time monitoring of spectral characteristics of microbubble (MB) acoustic emissions permits the prediction of increases in blood–brain barrier (BBB) permeability and of tissue damage in MB-mediated focused ultrasound (FUS) brain therapy. Si
Externí odkaz:
https://doaj.org/article/98e90d351e06466882a4e674293ece35
Publikováno v:
The Journal of the Acoustical Society of America. 153:2271-2284
Focused ultrasound (FUS) combined with intravenous microbubbles (MBs) has been shown to increase drug delivery to the spinal cord in animal models. Eventual clinical translation of such a technique in the sensitive spinal cord requires robust treatme
Publikováno v:
IEEE Trans Biomed Eng
GOAL: To develop a low-cost magnetic resonance imaging (MRI)-free transcranial focused ultrasound (FUS) system for microbubble-mediated therapy. METHODS: A 128-element 11 MHz array for skull localization was integrated within a 256-module multi-frequ
Autor:
Meaghan A. O'Reilly
Publikováno v:
The Journal of the Acoustical Society of America. 151:A197-A200
The R. Bruce Lindsay Award (formerly the Biennial Award) is presented in the Spring to a member of the Society who is no more than 10 years post terminal degree on 1 July at the time of Award acceptance and who, during a period of two or more years i
Publikováno v:
Annual Review of Biomedical Engineering. 23:89-113
Specialized features of vasculature in the central nervous system greatly limit therapeutic treatment options for many neuropathologies. Focused ultrasound, in combination with circulating microbubbles, can be used to transiently and noninvasively in
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Extensive studies on focused ultrasound (FUS)-mediated drug delivery through the blood–brain barrier have been published, yet little work has been published on FUS-mediated drug delivery through the blood-spinal cord barrier (BSCB). This work aims
Autor:
Rui Xu, Meaghan A. O'Reilly
Publikováno v:
The Journal of the Acoustical Society of America. 151(3)
Focused ultrasound treatments of the spinal cord may be facilitated using a phased array transducer and beamforming to correct spine-induced focal aberrations. Simulations can non-invasively calculate aberration corrections using x-ray computed tomog
Autor:
Rui Xu, Meaghan A. O'Reilly
Publikováno v:
IEEE Transactions on Biomedical Engineering. 67:256-267
Objective: To design and simulate the performance of two spine-specific phased arrays in sonicating targets spanning the thoracic spine, with the objective of efficiently producing controlled foci in the spinal canal. Methods: Two arrays (256 element
Publikováno v:
2021 IEEE International Ultrasonics Symposium (IUS).
Focused ultrasound blood-spinal cord barrier opening is a promising new method for improving the non-invasive delivery of therapeutic agents to the spinal cord. A custom 64-element phased array was built, based on the design of a component of a spine