Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Meagan Slater"'
Autor:
Mark S. Forman, Peter Orth, Ulrich Iserloh, Yusheng Wu, Hongwu Wang, William J. Greenlee, Reshma Kuvelkar, Xia Chen, Jack D. Scott, John Meredith, Lana M. Rossiter, Lynn A. Hyde, Robert A. Hodgson, Andrew Stamford, Julie A. Stone, Irina Kazakevich, Ganfeng Wang, Eric M. Parker, Eric J. Gilbert, Kathleen Cox, Corey O. Strickland, Sarah W. Li, Meagan Slater, Qin Jiang, Johannes H. Voigt, Hong Mei, Andrew Brunskill, Matthew E. Kennedy, Misiaszek Jeffrey A, Jared N. Cumming
Publikováno v:
Journal of Medicinal Chemistry. 59:10435-10450
Verubecestat 3 (MK-8931), a diaryl amide-substituted 3-imino-1,2,4-thiadiazinane 1,1-dioxide derivative, is a high-affinity β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor currently undergoing Phase 3 clinical evaluation for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88617ac0382047768a81e118b787b6ca
https://doi.org/10.1021/acs.jmedchem.6b00307
https://doi.org/10.1021/acs.jmedchem.6b00307
Publikováno v:
The Journal of organic chemistry. 74(24)
A total synthesis of the racemic natural product tylophorine [(+/-)-1] has been demonstrated using the palladium-catalyzed carboamination method developed by Wolfe and co-workers. In this case, an electron-rich aryl bromide 18 was prepared in four st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f38030caa5d14dec2d9306ccb67e87
https://pubmed.ncbi.nlm.nih.gov/19919084
https://pubmed.ncbi.nlm.nih.gov/19919084