Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Meagan R. Pitcher"'
Autor:
José A. Herrera, Christopher S. Ward, Meagan R. Pitcher, Alan K. Percy, Steven Skinner, Walter E. Kaufmann, Daniel G. Glaze, Xander H. T. Wehrens, Jeffrey L. Neul
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 4, Pp 363-371 (2015)
One quarter of deaths associated with Rett syndrome (RTT), an X-linked neurodevelopmental disorder, are sudden and unexpected. RTT is associated with prolonged QTc interval (LQT), and LQT-associated cardiac arrhythmias are a potential cause of unexpe
Externí odkaz:
https://doaj.org/article/ebf4109932af452a8babec28ce379258
Autor:
Loraine Maria Silva Andrade, Meagan R. Pitcher, Francisco de Assis Aquino Gondim, Paulo M.G. Sales, F.H. Rola
Publikováno v:
Neuroscience Letters. 633:196-201
Background The repetitive ElectroMagnetic Stimulation (rEMS) is an innocuous method applied to modulate neurocircuits in real-time to study the physiology of the central nervous system and treat neuropsychiatric conditions. Preliminary data suggest t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17350b0f0ddb4f02ba51f0179fdb4162
https://doi.org/10.1016/j.neulet.2016.09.038
https://doi.org/10.1016/j.neulet.2016.09.038
Autor:
João Quevedo, Meagan R. Pitcher
Publikováno v:
Expert Opinion on Drug Metabolism & Toxicology. 12:161-168
Development of xenobiotics that cross the blood-brain barrier in therapeutically-relevant quantities is an expensive and time-consuming undertaking. However, central nervous system diseases are an under-addressed cause of high mortality and morbidity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967fe121612540683ebcd1eeb956cce0
https://doi.org/10.1517/17425255.2016.1132307
https://doi.org/10.1517/17425255.2016.1132307
Autor:
Jeffrey L. Neul, Shelly A. Buffington, Mauro Costa-Mattioli, Jonathan K. Merritt, Amanda R. Fisher, José A. Herrera, Meagan R. Pitcher, N. Carolyn Schanen, Mikhail Y. Kochukov
Publikováno v:
Human Molecular Genetics. 24:2662-2672
Rett syndrome (RTT) is a severe neurodevelopmental disorder that is usually caused by mutations in Methyl-CpG-binding Protein 2 (MECP2). Four of the eight common disease causing mutations in MECP2 are nonsense mutations and are responsible for over 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458c2a3b6d1866a447c0ca8413751a15
https://doi.org/10.1093/hmg/ddv030
https://doi.org/10.1093/hmg/ddv030
Autor:
Manouchehr Hessabi, MinJae Lee, Katherine A. Loveland, Mohammad H. Rahbar, MacKinsey K.A. Christian, Ryan Krone, Amy Mitchell, Hanes M. Swingle, Meagan R. Pitcher, Donald G. Patterson, Sean Campbell
Publikováno v:
International Journal of Environmental Research and Public Health; Volume 14; Issue 11; Pages: 1425
International Journal of Environmental Research and Public Health, Vol 14, Iss 11, p 1425 (2017)
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, Vol 14, Iss 11, p 1425 (2017)
International Journal of Environmental Research and Public Health
Environmental exposure to organic endocrine disrupting chemicals, including dioxins, dibenzofurans, bisphenol A (BPA), and phthalates has been associated with neurodevelopmental disorders, including autism spectrum disorder (ASD). We conducted a pilo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e837159646bfd38c98506168805ac5a
Autor:
Walter E. Kaufmann, Jeffrey L. Neul, Meagan R. Pitcher, Rodney C. Samaco, Daniel G. Glaze, Christopher S. Ward, José A. Herrera, Teng-Wei Huang, Alan K. Percy, Steven A. Skinner, Alan Herron
Publikováno v:
PLoS ONE
Ward, CS; Huang, T-W; Herrera, JA; Samaco, RC; Pitcher, MR; Herron, A; et al.(2016). Loss of MeCP2 Causes Urological Dysfunction and Contributes to Death by Kidney Failure in Mouse Models of Rett Syndrome. PLOS ONE, 11(11). doi: 10.1371/journal.pone.0165550. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/4c231034
PLoS ONE, Vol 11, Iss 11, p e0165550 (2016)
PloS one, vol 11, iss 11
Ward, CS; Huang, T-W; Herrera, JA; Samaco, RC; Pitcher, MR; Herron, A; et al.(2016). Loss of MeCP2 Causes Urological Dysfunction and Contributes to Death by Kidney Failure in Mouse Models of Rett Syndrome. PLOS ONE, 11(11). doi: 10.1371/journal.pone.0165550. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/4c231034
PLoS ONE, Vol 11, Iss 11, p e0165550 (2016)
PloS one, vol 11, iss 11
Rett Syndrome (RTT) is a neurodevelopmental disorder characterized by loss of acquired skills during development, autonomic dysfunction, and an increased risk for premature lethality. Clinical experience identified a subset of individuals with RTT th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba533cd51904894ab6c4026e93613989
http://europepmc.org/articles/PMC5102405
http://europepmc.org/articles/PMC5102405
Autor:
Surabi Veeraragavan, Agnes J. Liang, Sirena Soriano, Janine M. LaSalle, Christopher S. Ward, Rodney C. Samaco, Jennie R. Green, Zhandong Liu, Shannon M. Hamilton, Ying Wooi Wan, Lisa Yuva, Daniel R. Connolly, Dag H. Yasui, Meagan R. Pitcher, Jeffrey L. Neul, Richard Paylor, Sharon G. Huang, Christopher M. McGraw
Publikováno v:
Human Molecular Genetics
Mouse models of the transcriptional modulator Methyl-CpG-Binding Protein 2 (MeCP2) have advanced our understanding of Rett syndrome (RTT). RTT is a 'prototypical' neurodevelopmental disorder with many clinical features overlapping with other intellec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ff27579c29030677497ed60b43bf1f
https://pubmed.ncbi.nlm.nih.gov/27365498
https://pubmed.ncbi.nlm.nih.gov/27365498
People with mood disorders experience pathologic periods of either elevated (manic) or depressed mood. A roadblock to pathophysiologic understanding and therapeutic development for mood disorders is the poor understanding of genetic and molecular mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::950b8ededc99dc7c2f9b3c82370c4fc7
https://doi.org/10.1016/b978-0-12-802733-2.00015-3
https://doi.org/10.1016/b978-0-12-802733-2.00015-3
Autor:
André F. Carvalho, Jessica A. Goularte, Lutiana R. Simões, Tatiana Barichello, P. Saigal, João Quevedo, Meagan R. Pitcher, Jaqueline S. Generoso, Marwa Badawy
Publikováno v:
Current molecular medicine. 16(2)
Bipolar disorder (BD) is a debilitating psychiatric disorder and a growing global public health issue. Notwithstanding BD has been conceptualized as a neuroprogressive illness, there are some evidences to suggest a role for neurodevelopmental pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5531f0062684adaa071dc13b53799d
https://pubmed.ncbi.nlm.nih.gov/26812921
https://pubmed.ncbi.nlm.nih.gov/26812921
Autor:
Allan Collodel, João Quevedo, Lutiana R. Simões, Tatiana Barichello, Jessica A. Goularte, Meagan R. Pitcher, Felipe Dal-Pizzol, Jaqueline S. Generoso
The central nervous system (CNS) is protected by a complex blood-brain barrier system; however, a broad diversity of virus, bacteria, fungi, and protozoa can gain access and cause illness. As pathogens replicate, they release molecules that can be re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce065e2aefb55e904d23a9cf3c3fc37e
https://europepmc.org/articles/PMC4567217/
https://europepmc.org/articles/PMC4567217/