Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Meagan L Wisniewski"'
Autor:
Susan M. Abdel-Rahman, Sami Albeiroti, D. Adam Algren, Justin Arnold, Amit Bansal, Adrian Baron, Melissa Beals, Marianne Benyon, Valkal Bhatt, Caren J. Blacker, Geza S. Bodor, Diane M. Boland, Vincent Buggs, Brian Capron, Dean C. Carlow, Amanda Chandler, Michael R. Christian, Uwe Christians, Jennifer M. Colby, Steven W. Cotten, Fiona Couper, Todd Crane, Kristine R. Crews, Saswati Das, Amitava Dasgupta, Brehon Davis, Sarah R. Delaney, Sridevi Devaraj, Mary H. Dudley (retired), Julia E. Esswein, Sheng Feng, Angela M. Ferguson, C. Clinton Frazee, Deborah French, Uttam Garg, Cindy George, Roy G. Gerona, Bruce A. Goldberger, Aaron Guinn, Lindsey J. Haldiman, Ara Hall, Yong Y. Han, Paul R. Hess, Andrea Ho, Tiffany Hollenbeck, Jessica A. Hvozdovich, Gregory Janis, Paul J. Jannetto, Jeffrey Jentzen, Leo Johnson, Kamisha L. Johnson-Davis, Heath A. Jolliff, Patricia M. Jones, Deven Juneja, Erin Kaleta, Amy B. Karger, Jaswinder Kaur, Kathleen A. Kelly, Hema Ketha, Jeff Knoblauch, Mikail Kraft, Matthew D. Krasowski, Robert Krumsick, Patrick B. Kyle, Jennifer A. Lowry, Andrew W. Lyon, Martha E. Lyon, Michael C. Malone, Michael M. Mbughuni, Christopher McCudden, Cornelia McDonald, Stacy E.F. Melanson, Chelsea Milito, Ross J. Miller, Alejandro R. Molinelli, Riley Murphy, Hari Nair, Vijayalakshmi Nandakumar, Prashant Nasa, John D. Nolen, Mushal Noor, John O. Ogunbileje, Anthony O. Okorodudu, Gabor Oroszi, Jayson V. Pagaduan, Wesley Palatnick, Khushbu Patel, Heather A. Paul, Amadeo Pesce, Mark Petersen, Brianna Peterson, Diane C. Peterson, Robert B. Pietak, Zoë Piggott, Bheemraj Ramoo, Alexandra Rapp, Jason L. Robinson, Cecilia M. Rosales, Nicola J. Rutherford-Parker, S.M. Hossein Sadrzadeh, Umar Salimi, Bjoern Schniedewind, Michael Scordo, Jesse Seegmiller, Hila Shaim, Leslie M. Shaw, Devin L. Shrock, Sarah Smiley, Christine L.H. Snozek, Kimia Sobhani, Alina G. Sofronescu, Heather M. Stieglitz, Roger W. Stone, Frederick G. Strathmann, Zengliu Su, Theresa Swift, Marius C. Tarau, Milton Tenenbein, Ruben Thanacoody, Marita Thompson, Stephen L. Thornton, Manoj Tyagi, Hana Vakili, Judith Sebestyen VanSickle, Ping Wang, Milad Webb, Elizabeth Wehner, Darcy Weidemann, Megan Weitzel, Meagan L. Wisniewski, Brian Wright, Fang Wu, Yifei Yang, Kiang-Teck J. Yeo, Paul E. Young, Y. Victoria Zhang, Viktor A. Zherebitskiy, Yusheng Zhu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76458f16eed1034cb3ffc05347a5cec0
https://doi.org/10.1016/b978-0-12-815846-3.00027-2
https://doi.org/10.1016/b978-0-12-815846-3.00027-2
Autor:
David Butler, Jeannie Hwang, Candice Estick, Akiko Nishiyama, Saranya Santhosh Kumar, Clive Baveghems, Hollie B Young-Oxendine, Meagan L Wisniewski, Ana Charalambides, Ben A Bahr
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20501 (2011)
Alzheimer's disease (AD) is an age-related neurodegenerative pathology in which defects in proteolytic clearance of amyloid β peptide (Aβ) likely contribute to the progressive nature of the disorder. Lysosomal proteases of the cathepsin family exhi
Externí odkaz:
https://doaj.org/article/dd7979c82b8c4ae38431d229954c1379
Autor:
Meng Shi, Jay W. Hooper, Nelson L. Michael, Shon Remich, James E. Moon, Judie B. Alimonti, Nicole M. Van Deusen, Paula Muñoz, Jocelyn Voell, Richard T. Davey, Barney S. Graham, Peter Silvera, Zonghui Hu, Linda L. Jagodzinski, H. Clifford Lane, Ramiro L. Gutierrez, Yan Zhou, Matthew D. Josleyn, Amy R. Castellano, John H. Beigel, Steven A. Kwilas, Patrick S. Twomey, Daphne A. Stanley, Kirsten S. Smith, Charles J. Link, Brian K. Martin, Kristopher M. Paolino, Wang Jing, W. Jay Ramsey, Holly R. Hack, Jason W. Bennett, Jason A. Regules, Olivier Tshiani Mbaya, Richard C. Ruck, Sheila A. Peel, Stephen J. Thomas, Nancy J. Sullivan, Julie E. Ledgerwood, Thomas P. Monath, Meagan L. Wisniewski
Publikováno v:
New England Journal of Medicine. 376:330-341
The worst Ebola virus disease (EVD) outbreak in history has resulted in more than 28,000 cases and 11,000 deaths. We present the final results of two phase 1 trials of an attenuated, replication-competent, recombinant vesicular stomatitis virus (rVSV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896727cbe2ec134d3e76766c077e5593
https://doi.org/10.1056/nejmoa1414216
https://doi.org/10.1056/nejmoa1414216
Publikováno v:
Rejuvenation Research. 15:189-197
Lysosomes are involved in degrading and recycling cellular ingredients, and their disruption with age may contribute to amyloidogenesis, paired helical filaments (PHFs), and α-synuclein and mutant huntingtin aggregation. Lysosomal cathepsins are upr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b60f173f47daeb5fe0883498ab6b749
https://doi.org/10.1089/rej.2011.1282
https://doi.org/10.1089/rej.2011.1282
Autor:
Dennis L. Wright, Meagan L. Wisniewski, Xueyun Zheng, Kishore Viswanathan, Ben A. Bahr, Michael T. Bowers, Megan Murray Gessel
Publikováno v:
Journal of Biological Chemistry. 287:6084-6088
The oligomerization of the amyloid-β protein (Aβ) is an important event in Alzheimer disease (AD) pathology. Developing small molecules that disrupt formation of early oligomeric states of Aβ and thereby reduce the effective amount of toxic oligom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a204e956c84d13694b087dbe043d120d
https://doi.org/10.1074/jbc.c111.328575
https://doi.org/10.1074/jbc.c111.328575
Autor:
Dennis J Hoover, Ben A. Bahr, Uzoma S. Ikonne, Dennis L. Wright, Meagan L. Wisniewski, Kishore Viswanathan, Jeannie Hwang
Publikováno v:
ACS medicinal chemistry letters. 3(11)
Lysosomes are involved in protein turnover and removing misfolded species, and their enzymes have the potential to offset the defect in proteolytic clearance that contributes to the age-related dementia Alzheimer's disease (AD). The weak cathepsin B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863eb66e2d0bc9312bee69f8694decd7
https://pubmed.ncbi.nlm.nih.gov/24900408
https://pubmed.ncbi.nlm.nih.gov/24900408
Autor:
Jeannie Hwang, Clive L. Baveghems, Ben A. Bahr, Meagan L. Wisniewski, Akiko Nishiyama, Ana Charalambides, Hollie B. Young-Oxendine, Candice Estick, Saranya Santhosh Kumar, David Butler
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20501 (2011)
PLoS ONE
PLoS ONE
Alzheimer's disease (AD) is an age-related neurodegenerative pathology in which defects in proteolytic clearance of amyloid β peptide (Aβ) likely contribute to the progressive nature of the disorder. Lysosomal proteases of the cathepsin family exhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa2095401a0b361925d4c5693fdcf71
http://europepmc.org/articles/PMC3112200?pdf=render
http://europepmc.org/articles/PMC3112200?pdf=render
Autor:
Caroline M. Coffey, Meagan L. Wisniewski, Lynne J. Anguish, Brenda G. Werner, John S. L. Parker, Louis G. Hom
Publikováno v:
Journal of virology. 85(1)
Mammalian orthoreoviruses induce apoptosis in vivo and in vitro ; however, the specific mechanism by which apoptosis is induced is not fully understood. Recent studies have indicated that the reovirus outer capsid protein μ1 is the primary determina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98af46c2d36d0996d01eb5949f5c0381
https://pubmed.ncbi.nlm.nih.gov/20980509
https://pubmed.ncbi.nlm.nih.gov/20980509
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. (12):1664-1674
Synaptic pathology in Alzheimer's disease brains is thought to involve soluble Aβ42 peptide. Here, sterile incubation in PBS caused small Aβ42 oligomer formation as well as heterogeneous, 6E10-immunopositive aggregates of 80–100kDa. The high mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a08715bf819eaf77cf770a1173f0a7
Publikováno v:
Journal of the North Carolina Academy of Science. 2013, Vol. 129 Issue 3, p130-164. 35p.