Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Meadhbh Á. Brennan"'
Autor:
Paul Humbert, Meadhbh Á. Brennan, Julien De Lima, Régis Brion, Annie Adrait, Céline Charrier, Bénédicte Brulin, Valérie Trichet, Yohann Couté, Frédéric Blanchard, Pierre Layrolle
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract In bone regeneration induced by the combination of mesenchymal stromal cells (MSCs) and calcium-phosphate (CaP) materials, osteoclasts emerge as a pivotal cell linking inflammation and bone formation. Favorable outcomes are observed despite
Externí odkaz:
https://doaj.org/article/8c0605303bff4042827151db8a18481c
Autor:
Meadhbh Á. Brennan, Mario Barilani, Francesco Rusconi, Julien de Lima, Luciano Vidal, Cristiana Lavazza, Lorenza Lazzari, Rosaria Giordano, Pierre Layrolle
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Bone marrow mesenchymal stem/stromal cells (BMSCs) show great promise for bone repair, however they are isolated by an invasive bone marrow harvest and their regenerative potential decreases with age. Conversely, cord blood can be collected
Externí odkaz:
https://doaj.org/article/7a981bfc3e294427a1124816c78b1f10
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100371- (2020)
Externí odkaz:
https://doaj.org/article/1cc2fc0fbb8443c6b703874399e1ea07
Autor:
Fiona E. Freeman, Meadhbh Á. Brennan, David C. Browe, Audrey Renaud, Julien De Lima, Daniel J. Kelly, Laoise M. McNamara, Pierre Layrolle
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
There is a distinct clinical need for new therapies that provide an effective treatment for large bone defect repair. Herein we describe a developmental approach, whereby constructs are primed to mimic certain aspects of bone formation that occur dur
Externí odkaz:
https://doaj.org/article/bf0e78b1e8b84b379f0b53a4593a193d
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
The healing of bone fractures is a well-orchestrated physiological process involving multiple cell types and signaling molecules interacting at the fracture site to replace and repair bone tissue without scar formation. However, when the lesion is to
Externí odkaz:
https://doaj.org/article/ab345a8855f44401a4e19c00dd458380
Autor:
Paul Humbert, Meadhbh Á. Brennan, Noel Davison, Philippe Rosset, Valérie Trichet, Frédéric Blanchard, Pierre Layrolle
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
A wide variety of biomaterials have been developed as both stabilizing structures for the injured bone and inducers of bone neoformation. They differ in chemical composition, shape, porosity, and mechanical properties. The most extensively employed a
Externí odkaz:
https://doaj.org/article/aab7e7e2a2cb45e0b63a95c1a062a192
Autor:
Pierre Avril, Louis-Romée Le Nail, Meadhbh Á. Brennan, Philippe Rosset, Gonzague De Pinieux, Pierre Layrolle, Dominique Heymann, Pierre Perrot, Valérie Trichet
Publikováno v:
Journal of Bone Oncology, Vol 5, Iss 1, Pp 5-14 (2016)
Conventional therapy of primary bone tumors includes surgical excision with wide resection, which leads to physical and aesthetic defects. For reconstruction of bone and joints, allografts can be supplemented with mesenchymal stem cells (MSCs). Simil
Externí odkaz:
https://doaj.org/article/f8272152646644a29a802088a3d4a37c
Autor:
Sara Gallinetti, Pierre Layrolle, Christina M. Tringides, David S. Monahan, Bénédicte Brulin, Paul Humbert, Meadhbh Á. Brennan, Maria-Pau Ginebra, Cristina Canal
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Universitat Politècnica de Catalunya (UPC)
In contrast to sintered calcium phosphates (CaPs) commonly employed as scaffolds to deliver mesenchymal stromal cells (MSCs) targeting bone repair, low temperature setting conditions of calcium deficient hydroxyapatite (CDHA) yield biomimetic topolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7a901d5be1dc5a71a2d4f16fe2d3f8
https://pubmed.ncbi.nlm.nih.gov/34520883
https://pubmed.ncbi.nlm.nih.gov/34520883
Publikováno v:
Bone Reports, Vol 13, Iss, Pp 100371-(2020)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a8963b1b9abb5fe698080dea57857c
http://www.sciencedirect.com/science/article/pii/S2352187220301315
http://www.sciencedirect.com/science/article/pii/S2352187220301315
Publikováno v:
Adv Funct Mater
The therapeutic benefits of mesenchymal stromal cell (MSC) transplantation have been attributed to their secreted factors, including extracellular vesicles (EVs) and soluble factors. The potential of employing the MSC secretome as an alternative acel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f9b57a14502e25d54cf12a4dbca78f9
https://pubmed.ncbi.nlm.nih.gov/32952493
https://pubmed.ncbi.nlm.nih.gov/32952493