Zobrazeno 1 - 10 of 8 960 pro vyhledávání: '"MeOH, methanol"'
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The effect of aliphatic, naphthenic, and aromatic hydrocarbons on production of reactive oxygen species and reactive nitrogen species in rat brain synaptosome fraction: the involvement of calcium, nitric oxide synthase, mitochondria, and phospholipase A11Abbreviations: BIM, bisindolylmaleimide; [Ca2+]i, concentration of intracellular calcium; ChAT, cholin acetyltransferase; CSA, cyclosporin A; DCF, 2′,7′-dichlorofluorescein; H2DCF-DA, 2′,7′-dichlorodihydrofluorescin diacetate; DEDA, dimethyleicosadienoic acid; ERK, extracellular signal-regulated kinases; Fura-2 AM, 5-oxazolecarboxylic acid, 2-(6-(bis(2-((acetyloxy)methoxy)-2-oxoethyl)amino)-5-(2-(bis(2-((acetyloxy)methoxy)-2oxoethyl)amino)-5-methylphenoxy)ethoxy)-2-benzofuranyl)-, (acetyloxy) methyl ester; GABA-T, gamma-aminobutyric acid transaminase; HBSS, Hanks’ balanced salt solution; La3+, lanthanum; MAPK, mitogen-activated protein kinase; MeHg, methyl mercury; MEK, extracellular signal-regulated protein kinase; MeOH, methanol; MTP, mitochondrial permeability transition pore; L-NAME, Nω-nitro-l-arginine methyl ester; NO·, nitrogen oxide; NOS, NO· synthase; O2·−, superoxide; PLA2, phospholipase A2; PKC, protein kinase C; RNS, reactive nitrogen species; ROS, reactive oxygen species; SOD, superoxide dismutase; TMB, 1,2,4-trimethylbenzene; TMCH, 1,2,4-trimethylcyclohexane; and U73122, 1-(6-[17beta-3-methoxyestra- 1,3,5(10)-trien- 17-yl]-aminohexyl)- 1H-pyrrole-2,5-dione
Autor: Oddvar Myhre, Frode Fonnum
Publikováno v: Biochemical Pharmacology. 62:119-128
This study investigated the effects of C7 and C9 aliphatic (n-heptane, n-nonane), naphthenic (methylcyclohexane, 1,2,4-trimethylcyclohexane (TMCH)) and aromatic (toluene, 1,2,4-trimethylbenzene (TMB)) hydrocarbons on the production of reactive oxygen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44ba27ac80b29eb3f63f26d0d661572
https://doi.org/10.1016/s0006-2952(01)00652-9
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Akademický článek
Phenanthroline-Mediated Photoelectrical Enhancement in Calix[4]arene-Functionalized Titanium-Oxo Clusters.
Autor: Hou, Jinle1 (AUTHOR) 19861527937@163.com, Huang, Chen1 (AUTHOR), Liu, Yuxin1 (AUTHOR), Fei, Pengfei1 (AUTHOR), Zhang, Dongxu1 (AUTHOR), Qu, Konggang1 (AUTHOR), Zi, Wenwen1 (AUTHOR), Huang, Xianqiang1 (AUTHOR) houjinle@lcu.edu.cn
Publikováno v: Molecules. Jun2024, Vol. 29 Issue 11, p2566. 14p.
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Akademický článek
Solvent Influence in the Synthesis of Lead(II) Complexes Containing Benzoate Derivatives.
Autor: Ayllón, José A.1 (AUTHOR) joseantonio.ayllon@uab.es, Vallcorba, Oriol2 (AUTHOR) ovallcorba@cells.es, Domingo, Concepción3 (AUTHOR) conchi@icmab.es
Publikováno v: Inorganics. Jan2024, Vol. 12 Issue 1, p24. 14p.
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4
Novel cationic cellulose beads for oral delivery of poorly water-soluble drugs
Autor: Fan Xie, Jernej Slak, Pedro Fardim, Guy Van den Mooter
Publikováno v: International journal of pharmaceutics: X. 5
Cellulose beads emerge as carriers for poorly water-soluble drugs due to their eco-friendly raw materials and favorable porous structure. However, drug dissolution may be limited by their poor swelling ability and the presence of closed pores caused
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6579617d352b2ad2633f9809284cdcc5
https://pubmed.ncbi.nlm.nih.gov/36593986
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5
LC-MS lipidomics of renal biopsies for the diagnosis of Fabry disease
Autor: Hoda Safari Yazd, Sina Feizbakhsh Bazargani, Christine A. Vanbeek, Kelli King-Morris, Coy Heldermon, Mark S. Segal, Richard Yost, William L. Clapp, Timothy J. Garrett
Publikováno v: Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 22, Iss, Pp 71-78 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab
Highlights • Fabry is an X-linked lysosomal storage disease with deficiency in α-galactosidase. • This deficiency results in the accumulation of glycosphinogolipids. • Diagnosis is often made by analysis of globotriaosylceramide in fluids and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc601d022917c183c0e3e9b796fc894b
https://doi.org/10.1016/j.jmsacl.2021.11.004
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6
Piper crocatum Ruiz & Pav. ameliorates wound healing through p53, E-cadherin and SOD1 pathways on wounded hyperglycemia fibroblasts
Autor: Dwi Aris Agung Nugrahaningsih, Firas Fneish, Christantie Effendy, Mae Sri Hartati Wahyuningsih, Gerhard Fortwengel, Andina Setyawati
Publikováno v: Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 12, Pp 7257-7268 (2021)
Graphical abstract
Highlights • The most active fraction of Piper crocatum Ruiz & Pav (FIV), originated from methanol extracts and wash benzene-soluble extracts, has diabetic wound healing activities on wounded hyperglycemia fibroblasts. • F
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae32efb978030766b31a20bb7a472cf
http://europepmc.org/articles/PMC8626332
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7
Loranthus acaciae: Alternative medicine for β-lactamase producer and methicillin-resistant Staphylococcus aureus
Autor: Ehssan H. Moglad
Publikováno v: Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 3, Pp 1835-1839 (2021)
Recently, we reported high antibacterial efficiency of Loranthus acaciae (LA) against different standard strains of bacteria including Methicillin-Resistant Staphylococcus aureus (MRSA). Therefore, this study aimed to confirm the effectiveness of LA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f48671069086e15ec37a38a3c44ef8ac
https://doi.org/10.1016/j.sjbs.2020.12.029
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8
Design, synthesis, molecular modeling, and biological evaluation of acrylamide derivatives as potent inhibitors of human dihydroorotate dehydrogenase for the treatment of rheumatoid arthritis
Autor: Tiantian Qi, Letian Zhang, Tingyuan Yang, Yating Luo, Shiliang Li, Fanxun Zeng, Lili Zhu, Guantian Yang, Yingfan Liang, Honglin Li, Rui Wang, Xiaoyong Xu
Publikováno v: Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 795-809 (2021)
Acta Pharmaceutica Sinica. B
Human dihydroorotate dehydrogenase (DHODH) is a viable target for the development of therapeutics to treat cancer and immunological diseases, such as rheumatoid arthritis (RA), psoriasis and multiple sclerosis (MS). Herein, a series of acrylamide-bas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe3ff9d9c75c7a612636b452a341e1f
http://www.sciencedirect.com/science/article/pii/S2211383520307590
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9
Alkaloids of Phaedranassa dubia (Kunth) J.F. Macbr. and Phaedranassa brevifolia Meerow (Amaryllidaceae) from Ecuador and its cholinesterase-inhibitory activity
Autor: Nora H. Oleas, Karen Acosta León, Alexandra Inca, Jessica Robles, Luciana R. Tallini, Jaume Bastida, Edison Osorio
Publikováno v: South African Journal of Botany
Dipòsit Digital de la UB
Universidad de Barcelona
Highlight • The role of Amaryllidaceae species from Ecuador as source of new drugs. • High amount of lycorine-type alkaloids in Phaedranassa dubia by GC-MS. • In vitro potential of Phaedranassa brevifolia as cholinesterase inhibitor. • Theore
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f464372f1d7b974e054bba8a5bca1f0
https://doi.org/10.1016/j.sajb.2020.09.007
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10
Exploitation of traditional healing properties, using the nanotechnology’s advantages: The case of curcumin
Autor: Sophia Hatziantoniou, Angeliki Liakopoulou, Elena A. Mourelatou
Publikováno v: Toxicology Reports, Vol 8, Iss, Pp 1143-1155 (2021)
Toxicology Reports
Graphical abstract
Highlights • Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, and Nanoemulsion are lipid nanocarriers with different matrix fluidity. • Lipid nanocarriers with different matrix fluidity may contribute differently
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a25315b7fa7fda8578e6a475872f0f1
http://www.sciencedirect.com/science/article/pii/S2214750021001037
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