LC-MS lipidomics of renal biopsies for the diagnosis of Fabry disease

Autor: Hoda Safari Yazd, Sina Feizbakhsh Bazargani, Christine A. Vanbeek, Kelli King-Morris, Coy Heldermon, Mark S. Segal, Richard Yost, William L. Clapp, Timothy J. Garrett

Publikováno v: Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 22, Iss, Pp 71-78 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab

Highlights • Fabry is an X-linked lysosomal storage disease with deficiency in α-galactosidase. • This deficiency results in the accumulation of glycosphinogolipids. • Diagnosis is often made by analysis of globotriaosylceramide in fluids and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc601d022917c183c0e3e9b796fc894b
https://doi.org/10.1016/j.jmsacl.2021.11.004

Piper crocatum Ruiz & Pav. ameliorates wound healing through p53, E-cadherin and SOD1 pathways on wounded hyperglycemia fibroblasts

Autor: Dwi Aris Agung Nugrahaningsih, Firas Fneish, Christantie Effendy, Mae Sri Hartati Wahyuningsih, Gerhard Fortwengel, Andina Setyawati

Publikováno v: Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 12, Pp 7257-7268 (2021)

Graphical abstract
Highlights • The most active fraction of Piper crocatum Ruiz & Pav (FIV), originated from methanol extracts and wash benzene-soluble extracts, has diabetic wound healing activities on wounded hyperglycemia fibroblasts. • F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae32efb978030766b31a20bb7a472cf
http://europepmc.org/articles/PMC8626332

Design, synthesis, molecular modeling, and biological evaluation of acrylamide derivatives as potent inhibitors of human dihydroorotate dehydrogenase for the treatment of rheumatoid arthritis

Autor: Tiantian Qi, Letian Zhang, Tingyuan Yang, Yating Luo, Shiliang Li, Fanxun Zeng, Lili Zhu, Guantian Yang, Yingfan Liang, Honglin Li, Rui Wang, Xiaoyong Xu

Publikováno v: Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 795-809 (2021)
Acta Pharmaceutica Sinica. B

Human dihydroorotate dehydrogenase (DHODH) is a viable target for the development of therapeutics to treat cancer and immunological diseases, such as rheumatoid arthritis (RA), psoriasis and multiple sclerosis (MS). Herein, a series of acrylamide-bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe3ff9d9c75c7a612636b452a341e1f
http://www.sciencedirect.com/science/article/pii/S2211383520307590

Exploitation of traditional healing properties, using the nanotechnology’s advantages: The case of curcumin

Autor: Sophia Hatziantoniou, Angeliki Liakopoulou, Elena A. Mourelatou

Publikováno v: Toxicology Reports, Vol 8, Iss, Pp 1143-1155 (2021)
Toxicology Reports

Graphical abstract
Highlights • Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, and Nanoemulsion are lipid nanocarriers with different matrix fluidity. • Lipid nanocarriers with different matrix fluidity may contribute differently

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a25315b7fa7fda8578e6a475872f0f1
http://www.sciencedirect.com/science/article/pii/S2214750021001037

Hydrodynamic cavitation efficiently inactivates potato virus Y in water

Autor: Katarina Bačnik, Tamara Košir, Arijana Filipić, Martin Petkovšek, Matevž Dular, Tadeja Lukežič, Maja Ravnikar, Mojca Zupanc, Meta Ješelnik, Ion Gutierrez Aguirre

Publikováno v: Ultrasonics Sonochemistry, Vol 82, Iss, Pp 105898-(2022)
Ultrasonics Sonochemistry

Graphical abstract
Highlights • Hydrodynamic cavitation inactivates PVY in water samples after 500 passes or less. • Hydrodynamic cavitation disrupts the viral capsid. • Hydrodynamic cavitation induces minor damage in the viral genome. •

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a11d9deb24a015a1d67d8d36c73d7e3
http://www.sciencedirect.com/science/article/pii/S1350417721004405