Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mélanie Bonnet"'
Autor:
François Virard, Stéphane Giraud, Mélanie Bonnet, Léa Magadoux, Laetitia Martin, Thuy Ha Pham, Najwa Skafi, Sophie Deneuve, Rita Frem, Bruno O. Villoutreix, Nawal Hajj Sleiman, Jonathan Reboulet, Samir Merabet, Vincent Chaptal, Cédric Chaveroux, Nader Hussein, Nicolas Aznar, Tanguy Fenouil, Isabelle Treilleux, Pierre Saintigny, Stéphane Ansieau, Serge Manié, Serge Lebecque, Toufic Renno, Isabelle Coste
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The quest for targeted therapies is critical in the battle against cancer. The RAS/MAP kinase pathway is frequently implicated in neoplasia, with ERK playing a crucial role as the most distal kinase in the RAS signaling cascade. Our previous
Externí odkaz:
https://doaj.org/article/5f91f695de8442caa6ead3b1243c6294
Autor:
Stéphanie Gon, Marie Loosveld, Thomas Crouzet, Delphine Potier, Mélanie Bonnet, Stéphanie O. Morin, Gérard Michel, Norbert Vey, Jacques A. Nunès, Bernard Malissen, Romain Roncagalli, Bertrand Nadel, Dominique Payet-Bornet
Publikováno v:
Haematologica, Vol 103, Iss 6 (2018)
Signaling through the αβT cell receptor (TCR) is a crucial determinant of T-cell fate and can induce two opposite outcomes during thymocyte development: cell death or survival and differentiation. To date, the role played by T-cell receptor in the
Externí odkaz:
https://doaj.org/article/5f4b2022c7054c69b8bfac278d0e4523
Autor:
Bertrand Montpellier, Christophe Picard, Jean Gabert, Marie Loosveld, Marie-Amélie Goujart, Lucie Hernandez, Lionel Chasson, Chantal Fossat, Jean-Marc Navarro, Stéphanie Gon, Bertrand Nadel, Mélanie Bonnet, Thomas Crouzet, Ester Morgado, Gérard Michel, Benoit Quilichini, Dominique Payet-Bornet
Publikováno v:
Genes, Chromosomes and Cancer. 53:52-66
MYC is a potent oncogene involved in ∼70% of human cancers, inducing tumorigenesis with high penetrance and short latency in experimental transgenic models. Accordingly, MYC is recognized as a major driver of T-cell acute lymphoblastic leukemia (T-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::294b6ec6afdd2c05b70dd24d3b3b401f
https://doi.org/10.1002/gcc.22117
https://doi.org/10.1002/gcc.22117
Autor:
Cyrille Hoarau, Eric Meffre, László Maródi, Mélanie Bonnet, Júlia Vasconcelos, Jean-Laurent Casanova, Héloïse Delagreverie, Laura Israel, Sandra K. Weller, Shen-Ying Zhang, Capucine Picard, Andrew C. Issekutz, Maya Chrabieh, Andrea Cerutti, Chaim M. Roifman, Yildiz Camcioglu, Peter D. Arkwright, Alexandre Alcaïs, Carlos Rodrigo, Simona Eva Zitnik, Ben Zion Garty, J.C. Weill, Anne Puel, C.A. Reynaud, Carlos Rodríguez-Gallego
Publikováno v:
Blood
We studied the distribution of peripheral B-cell subsets in patients deficient for key factors of the TLR-signaling pathways (MyD88, TIRAP/MAL, IL-1 receptor–associated kinase 4 [IRAK-4], TLR3, UNC-93B, TRIF). All TLRs, except TLR3, which signals t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8157d938d6bd8339b3c52920f3a12f5e
Autor:
Mélanie Bonnet, Marie Loosveld, Bertrand Montpellier, Jean-Marc Navarro, Benoit Quilichini, Christophe Picard, Julie Di Cristofaro, Chantal Fossat, Lucie Hernandez, Emilie Mamessier, Sandrine Roulland, Christine Formisano-Tréziny, Willem A Dik, Anton Langerak, Thomas Prebet, Norbert Vey, Gérard Michel, Jean Gabert, Jean Soulier, Elizabeth A. Macintyre, Vahid Asnafi, Dominique Payet-Bornet, Bertrand Nadel
Publikováno v:
Blood. 116:4188-4188
Abstract 4188 Cumulative evidence indicates that MYC, one of the major downstream effectors of NOTCH1, is a critical component of T-cell acute lymphoblastic leukemia (T-ALL) oncogenesis and a potential candidate for targeted therapy. However, MYC is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b0c03ee7495943e4d42c44b72e1e078
https://doi.org/10.1182/blood.v116.21.4188.4188
https://doi.org/10.1182/blood.v116.21.4188.4188
Autor:
Jean Gabert, Gérard Michel, Benoit Quilichini, Dominique Payet-Bornet, Christine Formisano-Tréziny, Mélanie Bonnet, Elizabeth Macintyre, Claude Bagnis, Sandrine Roulland, Bertrand Montpellier, Jean Soulier, Bertrand Nadel, Norbert Vey, Lucie Hernandez, Thomas Prebet, Chantal Fossat, Marie Loosveld, Jean-Marc Navarro, Julie Di Cristofaro, Anton W. Langerak, Vahid Asnafi, Christophe Picard, Ester Morgado, Emilie Mamessier, Willem A. Dik
Publikováno v:
HAL
Blood
Blood, American Society of Hematology, 2011, 117 (24), pp.6650-9. ⟨10.1182/blood-2011-02-336842⟩
Blood, 2011, 117 (24), pp.6650-9. ⟨10.1182/blood-2011-02-336842⟩
Blood, American Society of Hematology, 2011, 117 (24), pp.6650-6659. ⟨10.1182/blood-2011-02-336842⟩
Blood, American Society of Hematology, 2011, 117, pp.6650-6659
BLOOD
52nd Annual meeting of the American Society of hematology
52nd Annual meeting of the American Society of hematology, Dec 2010, Orlando, United States. pp.6650-6659, ⟨10.1182/blood-2011-02-336842⟩
Blood, 2011, 117 (24), pp.6650-9
Blood, American Society of Hematology, 2011, 117 (24), pp.6650-9
Blood, American Society of Hematology, 2011, 117 (24), pp.6650-9. 〈10.1182/blood-2011-02-336842〉
Blood, 117(24), 6650-6659. American Society of Hematology
Blood, 2011, 117 (24), pp.6650-6659. ⟨10.1182/blood-2011-02-336842⟩
Blood
Blood, American Society of Hematology, 2011, 117 (24), pp.6650-9. ⟨10.1182/blood-2011-02-336842⟩
Blood, 2011, 117 (24), pp.6650-9. ⟨10.1182/blood-2011-02-336842⟩
Blood, American Society of Hematology, 2011, 117 (24), pp.6650-6659. ⟨10.1182/blood-2011-02-336842⟩
Blood, American Society of Hematology, 2011, 117, pp.6650-6659
BLOOD
52nd Annual meeting of the American Society of hematology
52nd Annual meeting of the American Society of hematology, Dec 2010, Orlando, United States. pp.6650-6659, ⟨10.1182/blood-2011-02-336842⟩
Blood, 2011, 117 (24), pp.6650-9
Blood, American Society of Hematology, 2011, 117 (24), pp.6650-9
Blood, American Society of Hematology, 2011, 117 (24), pp.6650-9. 〈10.1182/blood-2011-02-336842〉
Blood, 117(24), 6650-6659. American Society of Hematology
Blood, 2011, 117 (24), pp.6650-6659. ⟨10.1182/blood-2011-02-336842⟩
Cumulative evidence indicates that MYC, one of the major downstream effectors of NOTCH1, is a critical component of T-cell acute lymphoblastic leukemia (T-ALL) oncogenesis and a potential candidate for targeted therapy. However, MYC is a complex onco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dcd3b0a173406bb6b9600c1a5d164dd
https://halshs.archives-ouvertes.fr/halshs-00739620
https://halshs.archives-ouvertes.fr/halshs-00739620