Development of a HPLC method for the determination of losartan urinary metabolic ratio to be used for the determination of CYP2C9 hydroxylation phenotypes

Autor: Dorado P, Machín E, de Andrés F, Me, Naranjo, Em, Peñas-Lledó, Adrián LLerena, Ceiba Fp Ribef, Consortium For The Ibero-American Network Of Pharmacogenomics

Publikováno v: Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1f65750d6b5229ec328a9326bd2c23f1
http://europepmc.org/abstract/med/23093260

Ethnic background and CYP2D6 genetic polymorphisms in Costa Ricans

Autor: Céspedes-Garro C, Jiménez-Arce G, Me, Naranjo, Barrantes R, Adrián LLerena, Ceiba Fp Ribef, Consortium Of The Ibero-American Network Of Pharmacogenetics Pharmacogenomics

Publikováno v: Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7260d2764ff12ab910cf365da024cb35
http://europepmc.org/abstract/med/25720195

Multi-institutional experience of genetic diagnosis in Ecuador: National registry of chromosome alterations and polymorphisms.

Autor: Paz-Y-Miño C; Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito, Ecuador., Yumiceba V; Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito, Ecuador., Moreta G; Servicio de Genética Médica, Hospital de Especialidades, Quito, Ecuador., Paredes R; Servicio de Genética Médica, Hospital de Especialidades, Quito, Ecuador., Ruiz M; CitoGen, Quito, Ecuador., Ocampo L; Laboratorio de Genética, Génica Laboratorios, Quito, Ecuador., Llamos Paneque A; Servicio de Genética Médica, Hospital de Especialidades, Quito, Ecuador., Ochoa Pérez C; Laboratorio de Citogenética, SOLCA Núcleo de Cuenca, Cuenca, Ecuador., Ruiz-Cabezas JC; Hospital 'Dr. Juan Tanca Marengo', SOLCA Matriz, Guayaquil, Ecuador.; Facultad de Medicina, Universidad Espíritu Santo, Guayaquil, Ecuador., Álvarez Vidal J; Centro de Diagnóstico y Estudios Biomédicos, Facultad de Ciencia Médicas, Universidad de Cuenca, Cuenca, Ecuador., Jiménez Torres I; Hospital Gineco Obstétrico Isidro Ayora, Ministerio de Salud Pública, Quito, Ecuador., Vargas-Vera R; Facultad de Ciencias Médicas, Universidad de Guayaquil, Guayaquil, Ecuador., Cruz F; Centro de Genética Médica, CEGEMED, Ministerio de Salud Pública, Quito, Ecuador., Guapi N VH; Hospital General Provincial 'Luis G. Dávila', Ministerio de Salud Pública, Tulcán, Ecuador., Montalván M; Centro de Investigaciones, Universidad Espíritu Santo, Guayaquil, Ecuador., Meneses Álvarez S; Hospital General Docente Ambato, Ministerio de Salud Pública, Ambato, Ecuador., Garzón Castro M; Servicio de Genética Médica, Hospital de Especialidades, Quito, Ecuador., Lamar Segura E; Servicio de Genética Médica, Hospital de Especialidades, Quito, Ecuador., Recalde Báez MA; Servicio de Genética Médica, Hospital de Especialidades, Quito, Ecuador., Naranjo ME; Servicio de Genética Médica, Hospital de Especialidades, Quito, Ecuador., Tambaco Jijón N; Servicio de Genética Médica, Hospital de Especialidades, Quito, Ecuador., Sinche M; Hospital 'Dr. Juan Tanca Marengo', SOLCA Matriz, Guayaquil, Ecuador., Licuy P; Hospital 'Dr. Juan Tanca Marengo', SOLCA Matriz, Guayaquil, Ecuador., Burgos R; Hospital 'Dr. Juan Tanca Marengo', SOLCA Matriz, Guayaquil, Ecuador., Porras-Borja F; Centro de Genética Médica, CEGEMED, Ministerio de Salud Pública, Quito, Ecuador., Echeverría-Garcés G; Centro de Genética Médica, CEGEMED, Ministerio de Salud Pública, Quito, Ecuador., Pérez-Villa A; Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito, Ecuador., Armendáriz-Castillo I; Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito, Ecuador., García-Cárdenas JM; Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito, Ecuador., Guerrero S; Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito, Ecuador., Guevara-Ramírez P; Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito, Ecuador., López-Cortés A; Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito, Ecuador., Zambrano AK; Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito, Ecuador., Leone PE; Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito, Ecuador.

Publikováno v: Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2020 Feb; Vol. 8 (2), pp. e1087. Date of Electronic Publication: 2019 Dec 12.

High frequency of CYP2D6 ultrarapid metabolizers in Spain: controversy about their misclassification in worldwide population studies.

Autor: Naranjo ME; CICAB Clinical Research Center, Extremadura University and Medical School, Badajoz, Spain., de Andrés F; CICAB Clinical Research Center, Extremadura University and Medical School, Badajoz, Spain., Delgado A; CICAB Clinical Research Center, Extremadura University and Medical School, Badajoz, Spain., Cobaleda J; CICAB Clinical Research Center, Extremadura University and Medical School, Badajoz, Spain.; Primary Health Care Center 'Ciudad Jardín', Badajoz, Spain., Peñas-Lledó EM; CICAB Clinical Research Center, Extremadura University and Medical School, Badajoz, Spain., LLerena A; CICAB Clinical Research Center, Extremadura University and Medical School, Badajoz, Spain.; CIBERSAM, Instituto de Salud Carlos III, Madrid, Spain.

Publikováno v: The pharmacogenomics journal [Pharmacogenomics J] 2016 Oct; Vol. 16 (5), pp. 485-90. Date of Electronic Publication: 2016 Jun 07.

High frequency and founder effect of the CYP3A4*20 loss-of-function allele in the Spanish population classifies CYP3A4 as a polymorphic enzyme.

Autor: Apellániz-Ruiz M; Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Inglada-Pérez L; 1] Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain [2] ISCIII Center for Biomedical Research on Rare Diseases (CIBERER), Madrid, Spain., Naranjo ME; CICAB Clinical Research Centre at Extremadura University Hospital and Medical School, Badajoz, Spain., Sánchez L; Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Mancikova V; Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Currás-Freixes M; Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., de Cubas AA; Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Comino-Méndez I; Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Triki S; Research Group on Molecular and Cellular Screening Processes, Laboratory of Microorganisms and Biomolecules, Centre of Biotechnology of Sfax, Sfax, Tunisia., Rebai A; Research Group on Molecular and Cellular Screening Processes, Laboratory of Microorganisms and Biomolecules, Centre of Biotechnology of Sfax, Sfax, Tunisia., Rasool M; Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia., Moya G; Pontificia Universidad Católica Argentina and Genos Laboratory, Buenos Aires, Argentina., Grazina M; Faculty of Medicine CNC-Centre for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal., Opocher G; Familial Cancer Clinic and Oncoendocrinology, Veneto Institute of Oncology, Padova, Italy., Cascón A; 1] Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain [2] ISCIII Center for Biomedical Research on Rare Diseases (CIBERER), Madrid, Spain., Taboada-Echalar P; Programa de Genética Humana, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile., Ingelman-Sundberg M; Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Carracedo A; 1] Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia [2] Fundación Pública de Medicina Xenómica-SERGAS, Grupo de Medicina Xenómica, CIBERER, IDIS, Santiago de Compostela, Spain., Robledo M; 1] Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain [2] ISCIII Center for Biomedical Research on Rare Diseases (CIBERER), Madrid, Spain., Llerena A; CICAB Clinical Research Centre at Extremadura University Hospital and Medical School, Badajoz, Spain., Rodríguez-Antona C; 1] Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain [2] ISCIII Center for Biomedical Research on Rare Diseases (CIBERER), Madrid, Spain.

Publikováno v: The pharmacogenomics journal [Pharmacogenomics J] 2015 Jun; Vol. 15 (3), pp. 288-92. Date of Electronic Publication: 2014 Nov 04.