Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Md Zahid, Akhter"'
Autor:
Md Zahid Akhter, Pascal Yazbeck, Mohammad Tauseef, Mumtaz Anwar, Faruk Hossen, Sayanti Datta, Vigneshwaran Vellingiri, Jagdish Chandra Joshi, Peter T. Toth, Nityanand Srivastava, Stephen Lenzini, Guangjin Zhou, James Lee, Mukesh K. Jain, Jae-Won Shin, Dolly Mehta
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114297- (2024)
Summary: The mechanical environment generated through the adhesive interaction of endothelial cells (ECs) with the matrix controls nuclear tension, preventing aberrant gene synthesis and the transition from restrictive to leaky endothelium, a hallmar
Externí odkaz:
https://doaj.org/article/bd516fbc0c824efbadb97d48af59e582
Autor:
Vijay Avin Balaji Ragunathrao, Vigneshwaran Vellingiri, Mumtaz Anwar, Md Zahid Akhter, Dolly Mehta
Publikováno v:
Molecular & Cellular Oncology, Vol 7, Iss 4 (2020)
We have recently uncovered that endothelial cell (EC) S1PR1 controls the effectiveness of VEGFR2 driven tumor angiogenesis. By using tumor ECs, EC-S1PR1−/- mice and S1PR1 antagonist, we showed that VEGF-VEGFR2 pathway requires EC-S1PR1-induced sign
Externí odkaz:
https://doaj.org/article/cfcf29e8f7f0470ebffc184f26b241a5
Autor:
Jagdish C. Joshi, Bhagwati Joshi, Ian Rochford, Sheikh Rayees, Md Zahid Akhter, Sukriti Baweja, Koteshwara Rao Chava, Mohammad Tauseef, Hazem Abdelkarim, Viswanathan Natarajan, Vadim Gaponenko, Dolly Mehta
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 4096-4109.e5 (2020)
Summary: Acute lung injury (ALI) is a lethal inflammatory lung disorder whose incidence is on the rise. Alveolar macrophages normally act to resolve inflammation, but when dysregulated they can provoke ALI. We demonstrate that monocyte-derived macrop
Externí odkaz:
https://doaj.org/article/a7510b0e0cab4569ac4fefd525cc8cd7
Autor:
Vijay Avin Balaji Ragunathrao, Mumtaz Anwar, Md Zahid Akhter, Alejandra Chavez, De Yu Mao, Viswanathan Natarajan, Sribalaji Lakshmikanthan, Magdalena Chrzanowska-Wodnicka, Arkadiusz Z. Dudek, Lena Claesson-Welsh, Jan K. Kitajewski, Kishore K. Wary, Asrar B. Malik, Dolly Mehta
Publikováno v:
Cell Reports, Vol 29, Iss 11, Pp 3472-3487.e4 (2019)
Summary: The vascular endothelial growth factor-A (VEGF-A)-VEGFR2 pathway drives tumor vascularization by activating proangiogenic signaling in endothelial cells (ECs). Here, we show that EC-sphingosine-1-phosphate receptor 1 (S1PR1) amplifies VEGFR2
Externí odkaz:
https://doaj.org/article/ca069aac595949f996eaf14ed636dcbc
Autor:
Md Zahid, Akhter, Jagdish, Chandra Joshi, Vijay Avin, Balaji Ragunathrao, Mark, Maienschein-Cline, Richard L, Proia, Asrar B, Malik, Dolly, Mehta
Publikováno v:
Circulation research. 129(2)
[Figure: see text].
Autor:
Jagdish C, Joshi, Bhagwati, Joshi, Ian, Rochford, Sheikh, Rayees, Md Zahid, Akhter, Sukriti, Baweja, Koteshwara Rao, Chava, Mohammad, Tauseef, Hazem, Abdelkarim, Viswanathan, Natarajan, Vadim, Gaponenko, Dolly, Mehta
Publikováno v:
Cell reports
SUMMARY Acute lung injury (ALI) is a lethal inflammatory lung disorder whose incidence is on the rise. Alveolar macrophages normally act to resolve inflammation, but when dysregulated they can provoke ALI. We demonstrate that monocyte-derived macroph
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 34:877-891
High mobility group A1 (HMGA1), a non-histone chromosomal protein, is highly expressed in a wide range of human cancers including cervical, breast, and prostate cancers. Therefore, hmga1 gene is considered as an attractive potential target for antica
Autor:
Md Zahid, Akhter, Surender K, Sharawat, Vikash, Kumar, Veena, Kochat, Zaffar, Equbal, Mallika, Ramakrishnan, Umesh, Kumar, Sandeep, Mathur, Lalit, Kumar, Asok, Mukhopadhyay
Publikováno v:
Oncogene. 37(16)
Epithelial ovarian carcinoma (EOC) patients often acquire resistance against common chemotherapeutic drugs like paclitaxel and cisplatin. The mechanism responsible for the same is ambiguous. We have identified a putative drug-resistant tumour cell ph
Autor:
Md. Zahid Akhter, Moganty R. Rajeswari
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 141:36-46
High mobility group A1 (HMGA1) non-histone chromatin protein is known as an architectural transcription factor that regulates transcription of various genes. HMGA1 is highly expressed in almost all human cancers and considered as a potent tumor marke
Autor:
Moganty R. Rajeswari, Md. Zahid Akhter
Publikováno v:
Journal of biomolecular structuredynamics. 35(4)
High-mobility group A1 (HMGA1) is a non-histone chromosomal protein, which is known as 'architectural' transcription factor that facilitates the assembly of 'enhanceosome.' Because of its elevated expression in a number of human malignancies, with ba