Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Md Yeunus Mian"'
Autor:
Stephanie M. Perez, Alexandra M. McCoy, Thomas D. Prevot, Md Yeunus Mian, Flavia R. Carreno, Alan Frazer, James M. Cook, Etienne Sibille, Daniel J. Lodge
Publikováno v:
Biological Psychiatry Global Open Science, Vol 3, Iss 1, Pp 78-86 (2023)
Background: Aberrant dopamine neuron activity is attributable to hyperactivity in hippocampal subfields driving a pathological increase in dopamine neuron activity, which is positively correlated with psychosis in humans. Evidence indicates that hipp
Externí odkaz:
https://doaj.org/article/084ff4c6137d42009c20604b31e46173
Autor:
Dishary Sharmin, Md Yeunus Mian, Michael Marcotte, Thomas D. Prevot, Etienne Sibille, Jeffrey M. Witkin, James M. Cook
Publikováno v:
Molecules, Vol 28, Iss 12, p 4771 (2023)
GABA mediates inhibitory actions through various GABAA receptor subtypes, including 19 subunits in human GABAAR. Dysregulation of GABAergic neurotransmission is associated with several psychiatric disorders, including depression, anxiety, and schizop
Externí odkaz:
https://doaj.org/article/acec2607b20b4845bf8d9d92e46a9997
Autor:
Paul McCusker, Md Yeunus Mian, Guanguan Li, Michael D Olp, V V N Phani Babu Tiruveedhula, Farjana Rashid, Lalit Kumar Golani, Ranjit S Verma, Brian C Smith, James M Cook, John D Chan
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007826 (2019)
Parasitic flatworm infections (e.g. tapeworms and fluke worms) are treated by a limited number of drugs. In most cases, control is reliant upon praziquantel (PZQ) monotherapy. However, PZQ is ineffective against sexually immature parasites, and there
Externí odkaz:
https://doaj.org/article/05d2c8e34a5f45dd9b752c21cfc4a2c1
Autor:
Guanguan Li, Amanda N. Nieman, Md Yeunus Mian, Nicolas M. Zahn, Brandon N. Mikulsky, Michael M. Poe, Kashi R. Methuku, Yongfeng Liu, James M. Cook, Douglas C. Stafford, Leggy A. Arnold
Publikováno v:
Molecules, Vol 25, Iss 17, p 3864 (2020)
Analgesic and anti-inflammatory properties mediated by the κ opioid receptor (KOR) have been reported for oxadiazole imidazodiazepines. Affinities determined by radioligand competition assays of more than seventy imidazodiazepines using cell homogen
Externí odkaz:
https://doaj.org/article/df69adecaff8428ea34ea1acbb5c2c98
Autor:
Kamal P. Pandey, Branka Divović, Farjana Rashid, Lalit K. Golani, Rok Cerne, Nicolas M. Zahn, Michelle Jean Meyer, Leggy A. Arnold, Dishary Sharmin, Md Yeunus Mian, Jodi L. Smith, Xingjie Ping, Xiaoming Jin, Arnold Lippa, V.V.N. Phani Babu Tiruveedhula, James M. Cook, Miroslav M. Savić, Jeffrey M. Witkin
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 385:50-61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79150d8e7e1712b0c4f2b466b3c9c84f
https://doi.org/10.1124/jpet.122.001362
https://doi.org/10.1124/jpet.122.001362
Autor:
Cook, Dishary Sharmin, Md Yeunus Mian, Michael Marcotte, Thomas D. Prevot, Etienne Sibille, Jeffrey M. Witkin, James M.
Publikováno v:
Molecules; Volume 28; Issue 12; Pages: 4771
GABA mediates inhibitory actions through various GABAA receptor subtypes, including 19 subunits in human GABAAR. Dysregulation of GABAergic neurotransmission is associated with several psychiatric disorders, including depression, anxiety, and schizop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::d03305460ff6816a667c06f6ebf301ae
Autor:
Md Yeunus Mian, Prithu Mondal, Dishary Sharmin, Kamal P. Pandey, Farjana Rashid, Sepideh Rezvanian, Lalit K. Golani, V.V.N. Phani Babu Tiruveedhula, Vilashini Rajaratnam, Shama P. Mirza, John D. Chan, Jeffrey M. Witkin, James M. Cook
Publikováno v:
Arkivoc. 2021:171-188
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9768ed2314885310c867ef6926a791f
https://doi.org/10.24820/ark.5550190.p011.712
https://doi.org/10.24820/ark.5550190.p011.712
Autor:
M. S. Rashid Roni, Nicolas M. Zahn, Gene T. Yocum, Daniel A. Webb, Md Yeunus Mian, Michelle J. Meyer, Anika S. Tylek, James M. Cook, Charles W. Emala, Douglas C. Stafford, Leggy A. Arnold
Publikováno v:
Drug Dev Res
MIDD0301 is being developed as an oral drug to relax airway smooth muscle and reduce lung inflammation in asthma. We report a comparative study of MIDD0301 and its S isomer (MIDD0301S) and found that the compounds have equivalent affinity for GABA(A)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40aeb95cbea0d6d642fc7cfe1230d732
https://doi.org/10.1002/ddr.21926
https://doi.org/10.1002/ddr.21926
Autor:
Nicolas M. Zahn, M. S. Rashid Roni, Gene T. Yocum, Michelle J. Meyer, Daniel A. Webb, Md Yeunus Mian, James M. Cook, Douglas C. Stafford, Charles W. Emala, Leggy A. Arnold
Publikováno v:
ACS Pharmacology & Translational Science. 5:80-88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c51d0f6fe72762c3b66bec25f008718
https://doi.org/10.1021/acsptsci.1c00238
https://doi.org/10.1021/acsptsci.1c00238
Autor:
Md Yeunus Mian, Branka Divović, Dishary Sharmin, Kamal P. Pandey, Lalit K. Golani, V. V. N. Phani Babu Tiruveedhula, Rok Cerne, Jodi L. Smith, Xingjie Ping, Xiaoming Jin, Gregory H. Imler, Jeffrey R. Deschamps, Arnold Lippa, James M. Cook, Miroslav M. Savić, James Rowlett, Jeffrey M. Witkin
Publikováno v:
ACS Omega
Imidazodiazepine (5-(8-ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazole[1,5-α][1,4]diazepin-3-yl) oxazole or KRM-II-81) is a potentiator of GABAA receptors (a GABAkine) undergoing preparation for clinical development. KRM-II-81 is active against many s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5ead1f3451334a5b9575b1f28e4be7
https://pubmed.ncbi.nlm.nih.gov/35967038
https://pubmed.ncbi.nlm.nih.gov/35967038