Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Md Nasrul Hoda"'
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 2051 (2022)
The restoration of cerebral blood flow (CBF) to achieve brain tissue oxygenation (PbtO2) is the primary treatment for ischemic stroke, a significant cause of adult mortality and disability worldwide. Nitric oxide (NO) and its bioactive s-nitrosylated
Externí odkaz:
https://doaj.org/article/382af0125bc24d2292f36dd3e35d7f77
Publikováno v:
Biomolecules, Vol 11, Iss 11, p 1587 (2021)
The COVID-19 pandemic has escalated the occurrence of hypoxia including thrombotic stroke worldwide, for which nitric oxide (NO) therapy seems very promising and translatable. Therefore, various modes/routes of NO-delivery are now being tested in dif
Externí odkaz:
https://doaj.org/article/97e37942949346cb8607360ffa77201c
Autor:
Yiming Xu, Yong Wang, Siyuan Yan, Yaqi Zhou, Qiuhua Yang, Yue Pan, Xianqiu Zeng, Xiaofei An, Zhiping Liu, Lina Wang, Jiean Xu, Yapeng Cao, David J Fulton, Neal L Weintraub, Zsolt Bagi, Md Nasrul Hoda, Xiaoling Wang, Qinkai Li, Mei Hong, Xuejun Jiang, Detlev Boison, Christian Weber, Chaodong Wu, Yuqing Huo
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 9, Pp 1263-1278 (2017)
Abstract The nucleoside adenosine is a potent regulator of vascular homeostasis, but it remains unclear how expression or function of the adenosine‐metabolizing enzyme adenosine kinase (ADK) and the intracellular adenosine levels influence angiogen
Externí odkaz:
https://doaj.org/article/76c3e705dd9743499adc42614850974d
Publikováno v:
Brain Circulation, Vol 1, Iss 2, Pp 133-139 (2015)
There is a strong link between hypoperfusion and white matter (WM) damage in patients with leukoaraiosis and vascular cognitive impairment (VCI). Other than management of vascular risk factors, there is no treatment for WM damage and VCI that delays
Externí odkaz:
https://doaj.org/article/0d0e56cb0a544b37861cf9c5a0ce616c
Autor:
Xu Qin, Md Nasrul Hoda, Cristiano Susin, Julie N. Wheeler, Brendan Marshall, Libby Perry, Nancy Saad, Lin Yin, Ranya Elsayed, Mohammed Elsalanty, Rafik Abdelsayed, Jack C. Yu, Krishnan M. Dhandapani, Omid Akbari, Mahmood S. Mozaffari, Babak Baban
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Innate lymphoid cells (ILCs) are master regulators of immune and inflammatory responses, but their own regulatory mechanisms and functional roles of their subtypes (i.e., ILC1s–ILC3s) remain largely unresolved. Interestingly, AMP-activated protein
Externí odkaz:
https://doaj.org/article/6cadc85d187e48a798c02de76e2f7eb8
Autor:
Insha Zahoor, Hamid Suhail, Indrani Datta, Mohammad Ejaz Ahmed, Laila M. Poisson, Jeffrey Waters, Faraz Rashid, Rui Bin, Jaspreet Singh, Mirela Cerghet, Ashok Kumar, Md Nasrul Hoda, Ramandeep Rattan, Ashutosh K. Mangalam, Shailendra Giri
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(25)
Metabolic aberrations impact the pathogenesis of multiple sclerosis (MS) and possibly can provide clues for new treatment strategies. Using untargeted metabolomics, we measured serum metabolites from 35 patients with relapsing-remitting multiple scle
Autor:
David C, Hess, Mohammad Badruzzaman, Khan, Pradip, Kamat, Kumar, Vaibhav, Krishnan M, Dhandapani, Babak, Baban, Jennifer L, Waller, Md Nasrul, Hoda, Rolf Ankerlund, Blauenfeldt, Grethe, Andersen
Publikováno v:
Cond Med
Remote ischemic conditioning (RIC) is a promising safe, feasible, and inexpensive treatment for acute stroke, both ischemic and hemorrhagic. It is applied with a blood pressure cuff on the limbs and is ideal for the prehospital setting. RIC is a form
Remote Ischemic Post-Conditioning Therapy is Protective in Mouse Model of Traumatic Optic Neuropathy
Autor:
Muhammad, Nadeem, Adam, Kindelin, Laura, Mahady, Kanchan, Bhatia, Md Nasrul, Hoda, Andrew F, Ducruet, Saif, Ahmad
Publikováno v:
Neuromolecular medicine. 23(3)
Traumatic optic neuropathy (TON) is characterized by visual dysfunction after indirect or direct injury to the optic nerve following blunt head trauma. TON is associated with increased oxidative stress and inflammation resulting in retinal ganglion c
Autor:
Ali S. Arbab, Mohammad B Khan, Manish Kumar, Md. Nasrul Hoda, David C. Hess, Babak Baban, Zenab T. Khan, Krishnan M. Dhandapani, Ayobami Ward, Kumar Vaibhav, Bhagelu R. Achyut, Molly Braun
Publikováno v:
Brain, Behavior, and Immunity. 68:224-237
Inflammation is an important mediator of secondary neurological injury after traumatic brain injury (TBI). Endocannabinoids, endogenously produced arachidonate based lipids, have recently emerged as powerful anti-inflammatory compounds, yet the molec
Autor:
Babak Baban, David Yashar, Mohammad B Khan, Sherif Hafez, Md. Nasrul Hoda, David C. Hess, Krishnan M. Dhandapani, Hesam Khodadadi, Yong Li, Molly Braun, Shahneela Siddiqui, Róbert Bátori, Kumar Vaibhav
Publikováno v:
Stroke. 50
Background and Purpose: There is presently no specific therapy for the treatment of VCID. We reported that daily C-RIC (4mo) is effective in young mice by improving cerebral blood flow (CBF), minimizing white matter (WM) damage and improving function