Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Md Khurshidul Hassan"'
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191377 (2018)
Eukaryotic translation factors, especially initiation factors have garnered much attention with regards to their role in the onset and progression of different cancers. However, the expression levels and prognostic significance of translation elongat
Externí odkaz:
https://doaj.org/article/79638e2c3e9b464fa3076d7b6c712235
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186977 (2017)
IQGAPs is a family of proteins which comprises three members, in humans. The expression pattern and role of IQGAP1 has been well established in many cancers, whereas those of IQGAP2 and IQGAP3, have mostly remained unexplored. We used available large
Externí odkaz:
https://doaj.org/article/3cfef730cd7e4209aa1b3e657832ca22
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-22 (2024)
Abstract Protein synthesis via translation is a central process involving several essential proteins called translation factors. Although traditionally described as cellular “housekeepers,” multiple studies have now supported that protein initiat
Externí odkaz:
https://doaj.org/article/954fe569e9644e4a83c2f5f3061c3558
Autor:
Dinesh Kumar, Saket Awadesbhai Patel, Md. Khurshidul Hassan, Nachiketa Mohapatra, Niharika Pattanaik, Manjusha Dixit
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-14 (2021)
Abstract IQGAP2, a member of the IQGAP family, functions as a tumor suppressor in most of the cancers. Unlike IQGAP1 and IQGAP3, which function as oncogenes in breast cancer, the role of IQGAP2 is still unexplored. Here we report a reduced expression
Externí odkaz:
https://doaj.org/article/8af3ce9237fa42e9aaac89c510024ce0
Autor:
Saket Awadesbhai Patel, Dinesh Kumar, Md. Khurshidul Hassan, Nachiketa Mohapatra, Manjusha Dixit, Niharika Pattanaik
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 4, Pp 1-14 (2021)
Cell Death and Disease, Vol 12, Iss 4, Pp 1-14 (2021)
IQGAP2, a member of the IQGAP family, functions as a tumor suppressor in most of the cancers. Unlike IQGAP1 and IQGAP3, which function as oncogenes in breast cancer, the role of IQGAP2 is still unexplored. Here we report a reduced expression of IQGAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14fdb9e2ac85adca1a91c6ce65df39b
https://doi.org/10.1038/s41419-021-03673-0
https://doi.org/10.1038/s41419-021-03673-0
Autor:
Subhadip Mukhopadhyay, Prashanta Kumar Panda, Birendra Behera, Chandan Kanta Das, Md Khurshidul Hassan, Durgesh Nandini Das, Niharika Sinha, Akalabya Bissoyi, Krishna Pramanik, Tapas K. Maiti, Sujit K. Bhutia
Publikováno v:
Food and Chemical Toxicology. 162:112893
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c871728bb892d4b4617b32c8fdbdcccb
https://doi.org/10.1016/j.fct.2022.112893
https://doi.org/10.1016/j.fct.2022.112893
Publikováno v:
Bioorganicmedicinal chemistry. 30
Small interfering RNA (siRNA) exhibits gene-specific RNAi activity by the formation of RISC complex with mRNA of gene. The structural modification of siRNA at appropriate positions affects the structure of RISC complex and then RNAi activity. The mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e9586b595f3c6074d65a249d3d0936
https://pubmed.ncbi.nlm.nih.gov/33316720
https://pubmed.ncbi.nlm.nih.gov/33316720
Autor:
Nachiketa Mohapatra, Niharika Pattanaik, Dinesh Kumar, Md. Khurshidul Hassan, Manjusha Dixit, Saket Awadhesbhai Patel
Publikováno v:
Life sciences. 246
Aims Glioblastomas are highly aggressive brain tumors with a very poor survival rate. EEF1A2, the proto-oncogenic isoform of the EEF1A translation factor family, has been found to be overexpressed and promoting tumorigenesis in multiple cancers. Inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3eb5bcd18df73132aff6f1e23dc208
https://pubmed.ncbi.nlm.nih.gov/32032648
https://pubmed.ncbi.nlm.nih.gov/32032648
IQGAP2 is a member of IQGAPs scaffolding protein family. It has been reported as a tumor suppressor in various cancers, as well as, an oncogene in some cancers, suggesting organ specific role. Need to identify therapeutic targets which function in ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f96f1d8e6fe014e218c7b9693a0578
https://doi.org/10.1101/651034
https://doi.org/10.1101/651034
Publikováno v:
Life Sciences. 262:118553
Aims Ever since EEF1A2's identification as a putative oncogene in breast cancer, it has stimulated curiosity due to its contrasting role in predicting the prognostic values in breast cancer patients. Contradicting reports suggest it to be playing a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9bff28935b40ddeb881f60c9d16b986
https://doi.org/10.1016/j.lfs.2020.118553
https://doi.org/10.1016/j.lfs.2020.118553