Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mckenzie K. Lehman"'
Autor:
McKenzie K. Lehman
Publikováno v:
mSphere, Vol 9, Iss 7 (2024)
ABSTRACT McKenzie Lehman works in the field of bacterial pathogenesis and metabolism. In this mSphere of Influence article, she reflects on how three papers entitled “Glycolytic dependency of high-level nitric oxide resistance and virulence in Stap
Externí odkaz:
https://doaj.org/article/c7299ee57f6e43628c8c9515edae5496
Autor:
Itidal Reslane, Cortney R. Halsey, Amanda Stastny, Barbara J. Cabrera, Jongsam Ahn, Dhananjay Shinde, Madeline R. Galac, Margaret F. Sladek, Fareha Razvi, McKenzie K. Lehman, Kenneth W. Bayles, Vinai C. Thomas, Luke D. Handke, Paul D. Fey
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Previous studies have found that arginine biosynthesis in Staphylococcus aureus is repressed via carbon catabolite repression (CcpA), and proline is used as a precursor. Unexpectedly, however, robust growth of S. aureus is not observed in co
Externí odkaz:
https://doaj.org/article/76799a176f054de2b81bfcac6d82938e
Autor:
McKenzie K. Lehman, Austin S. Nuxoll, Kelsey J. Yamada, Tammy Kielian, Steven D. Carson, Paul D. Fey
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Staphylococcus aureus has the ability to cause infections in multiple organ systems, suggesting an ability to rapidly adapt to changing carbon and nitrogen sources. Although there is little information about the nutrients available at specif
Externí odkaz:
https://doaj.org/article/5ffaa02fcfd0439e9fedfded29dfb694
Autor:
Cortney R. Halsey, Shulei Lei, Jacqueline K. Wax, Mckenzie K. Lehman, Austin S. Nuxoll, Laurey Steinke, Marat Sadykov, Robert Powers, Paul D. Fey
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT Staphylococcus aureus must rapidly adapt to a variety of carbon and nitrogen sources during invasion of a host. Within a staphylococcal abscess, preferred carbon sources such as glucose are limiting, suggesting that S. aureus survives throug
Externí odkaz:
https://doaj.org/article/7e448f943df6474093a5fa3ab2f51302
Autor:
McKenzie K. Lehman, Natalie A. Sturd, Fareha Razvi, Dianne L. Wellems, Steven D. Carson, Paul D. Fey
Publikováno v:
PLOS Pathogens. 19:e1011098
Proline acquired via specific transporters can serve as a proteinogenic substrate, carbon and nitrogen source, or osmolyte. Previous reports have documented that Staphylococcus aureus, a major community and nosocomial pathogen, encodes at least four
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7e8713abed47ccb2ce506d9dea1eadc
https://doi.org/10.1371/journal.ppat.1011098
https://doi.org/10.1371/journal.ppat.1011098
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42244 (2012)
The most prominent murein hydrolase of Staphylococcus aureus, AtlA, is a bifunctional enzyme that undergoes proteolytic cleavage to yield two catalytically active proteins, an amidase (AM) and a glucosaminidase (GL). Although the bifunctional nature
Externí odkaz:
https://doaj.org/article/c428779841944d05909489b46c3657a1
Autor:
Austin S. Nuxoll, Paul D. Fey, Steven D. Carson, McKenzie K. Lehman, Tammy Kielian, Kelsey J. Yamada
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
mBio, Vol 10, Iss 2, p e02553-18 (2019)
mBio, Vol 10, Iss 2, p e02553-18 (2019)
Staphylococcus aureus has the ability to cause infections in multiple organ systems, suggesting an ability to rapidly adapt to changing carbon and nitrogen sources. Although there is little information about the nutrients available at specific sites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24e93eef7d0ad2ee029257c4ffdf828
https://journals.asm.org/doi/10.1128/mBio.02553-18
https://journals.asm.org/doi/10.1128/mBio.02553-18
Autor:
McKenzie K. Lehman, Robert Powers, Vinai Chittezham Thomas, Paul D. Fey, Tammy Kielian, Sujata S. Chaudhari, Kelsey J. Yamada, Fatema Bhinderwala, Kirk W. Foster, Chunyi Zhou
Publikováno v:
PLoS Pathogens, Vol 15, Iss 1, p e1007538 (2019)
PLoS Pathogens
PLoS Pathogens
Staphylococcus aureus causes acute and chronic infections resulting in significant morbidity. Urease, an enzyme that generates NH3 and CO2 from urea, is key to pH homeostasis in bacterial pathogens under acidic stress and nitrogen limitation. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7526665b0b914cfe6a67e7217a4b6e1e
https://doaj.org/article/b6a142c54e844649a86a7814448d4144
https://doaj.org/article/b6a142c54e844649a86a7814448d4144
Autor:
Marat R. Sadykov, Derek E. Moormeier, Batu K. Sharma-Kuinkel, McKenzie K. Lehman, Kenneth W. Bayles, Indranil Biswas, Jennifer L. Endres, Jeffrey L. Bose
Publikováno v:
Molecular Microbiology. 95:723-737
Recent studies have demonstrated that expression of the Staphylococcus aureus lrgAB operon is specifically expressed within tower structures during biofilm development. To gain a better understanding of the mechanisms underlying this spatial control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84d6baf9e9634fa6e30f3ebf1e3df140
https://doi.org/10.1111/mmi.12902
https://doi.org/10.1111/mmi.12902
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1373
Methods used to understand the function of a gene/protein are one of the hallmarks of modern molecular genetics. The ability to genetically manipulate bacteria has become a fundamental tool in studying these organisms and while basic cloning has beco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0c57657ff6f0a69e8eed858f46e1303
https://pubmed.ncbi.nlm.nih.gov/25646609
https://pubmed.ncbi.nlm.nih.gov/25646609