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pro vyhledávání: '"Mcguinness E. Barry"'
Autor:
Cowley Phillip, Bevan Nicola, Mcguinness E. Barry, Brown J. Thomas, Szybut Clare, Wise Alan, Trewick C. Sarah
Publikováno v:
European Journal of Cancer. 51:S5
Background TDO (tryptophan 2,3-dioxygenase) and IDO (indoleamine 2,3-dioxygenase) catalyse the oxidation of tryptophan leading to the formation of immunesuppressive kynurenine pathway (KP) metabolites and dampening the immune response in the tumour e