Zobrazeno 1 - 10
of 15
pro vyhledávání: '"McWayne Weche"'
Publikováno v:
Pharmacological Research, Vol 190, Iss , Pp 106730- (2023)
We reported previously that α1-adrenoceptor (α1-AR) ligands inhibit chemokine receptor (CR) heteromerization partners of α1B/D-AR. The underlying mechanisms are unknown and in vivo evidence for such effects is missing. Utilizing CCR2 and α1B-AR a
Externí odkaz:
https://doaj.org/article/6b8bec8df6bc403c88e6d0b85bc1297a
Autor:
McWayne Weche, Anthony J DeSantis, Michelle Y McGee, Garrett A Enten, Xianlong Gao, Matthias Majetschak
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284472 (2023)
Systemic concentrations of chemokine CCL2, an agonist at chemokine receptors CCR2/3/5, have been associated with hemodynamic instability after traumatic-hemorrhagic shock. We reported previously that the CCR2 antagonist INCB3284 prevents cardiovascul
Externí odkaz:
https://doaj.org/article/07d89c8c650f447ba74b500f85856555
Autor:
Anthony J. DeSantis, MD, McWayne Weche, MD, Garrett A. Enten, MS, Xianlong Gao, MD, PhD, Matthias Majetschak, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 4, Iss 5, p e0701 (2022)
OBJECTIVES:. Clinical correlations suggest that systemic chemokine (C-C motif) ligand (CCL) 2 release may contribute to blood pressure regulation and the development of hemodynamic instability during the early inflammatory response to traumatic-hemor
Externí odkaz:
https://doaj.org/article/112e5460702a4fdf96f1b6d272f7f10b
Autor:
Xianlong Gao, Anthony J. DeSantis, Garrett A. Enten, McWayne Weche, Jorge E. Marcet, Matthias Majetschak
Publikováno v:
FEBS Letters. 596:2706-2716
Autor:
Meagan D. Read, Rohan Shah, Haroon Janjua, Salvatore Docimo, Emily A. Grimsley, McWayne Weche, Paul C. Kuo
Publikováno v:
The American Journal of Surgery.
Autor:
Xianlong, Gao, Anthony J, DeSantis, Garrett A, Enten, McWayne, Weche, Jorge E, Marcet, Matthias, Majetschak
Publikováno v:
FEBS lettersReferences. 596(20)
Previously, we reported that chemokine (C-C motif) receptor 2 (CCR2) heteromerizes with α
Autor:
Garrett A, Enten, Xianlong, Gao, Hannah R, Strzelinski, McWayne, Weche, Stephen B, Liggett, Matthias, Majetschak
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(20)
It is known that catecholamines regulate innate immune functions. The underlying mechanisms, however, are not well understood. Here we show that at least 20 members of the human chemokine receptor (CR) family heteromerize with one or more members of
Autor:
Garrett A. Enten, Xianlong Gao, Hannah R. Strzelinski, McWayne Weche, Stephen B. Liggett, Matthias Majetschak
Publikováno v:
Proceedings of the National Academy of Sciences. 119
SignificanceHere we show that most chemokine receptors (CRs) form heteromeric complexes with α1-adrenergic receptors (ARs) in recombinant systems and that such heteromers are detectable in human monocytes and in the human monocytic leukemia cell lin
Publikováno v:
Journal of Laparoendoscopic & Advanced Surgical Techniques. 30:110-116
Background: Achalasia and other esophageal motility disorders are incurable diseases for which palliation and symptom relief are the goals. One of the many ways these diseases are treated is with either a Heller myotomy or, now more commonly, per-ora
Autor:
Anthony J. DeSantis, Haroon M. Janjua, Daniela Moiño, Graham Davis, Victoria Sands, McWayne Weche, Paul C. Kuo, Joseph Sujka, Christopher DuCoin
Publikováno v:
Surgical endoscopy. 36(11)
Many surgical disciplines have demonstrated superior outcomes when procedures are performed at "high-volume". Esophagomyotomy is commonly performed for achalasia, however it's unclear what constitutes "high-volume" for this procedure, and if individu