TH-MYCNtumors, but not tumor-derived cell lines, are adrenergic lineage, GD2+, and responsive to anti-GD2 antibody therapy

Autor: McNerney, KO, Karageorgos, S, Ferry, GM, Wolpaw, AJ, Burudpakdee, C, Khurana, P, Toland, CN, Vemu, R, Vu, A, Hogarty, MD, Bassiri, H

Publikováno v: OncoImmunology; December 2022, Vol. 11 Issue: 1

INSPIRED Symposium Part 5: Expanding the Use of CAR T Cells in Children and Young Adults.

Autor: Talleur AC; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, Tennessee. Electronic address: atalleur@stjude.org., Fabrizio VA; Department of Pediatric Hematology, Oncology, and Blood and Marrow Transplant, Children's Hospital Colorado/University of Colorado Anschutz, Aurora, Colorado., Aplenc R; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Grupp SA; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Mackall C; Department of Pediatrics, Department of Medicine, Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford University School of Medicine, Stanford University, Stanford, California., Majzner R; Dana-Farber Cancer Institute, Boston, Massachusetts., Nguyen R; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Rouce R; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, Texas., Moskop A; Division of Hematology/Oncology/Blood and Marrow Transplantation, Department of Pediatrics, Medical College of Wisconsin and Children's Wisconsin, Milwaukee, Wisconsin., McNerney KO; Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

Publikováno v: Transplantation and cellular therapy [Transplant Cell Ther] 2024 Jun; Vol. 30 (6), pp. 565-579. Date of Electronic Publication: 2024 Apr 07.

INSPIRED Symposium Part 3: Prevention and Management of Pediatric Chimeric Antigen Receptor T Cell-Associated Emergent Toxicities.

Autor: McNerney KO; Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois. Electronic address: kmcnerney@luriechildrens.org., Hsieh EM; Pediatric Hematology/Oncology, Cancer and Blood Disease Institute, Children's Hospital Los Angeles, Norris Comprehensive Cancer Center, Keck School of Medicine of USC, Los Angeles, California., Shalabi H; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Epperly R; Department of Bone Marrow Transplant, St. Jude Children's Research Hospital, Memphis, Tennessee., Wolters PL; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Hill JA; Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Center, Seattle, Washington., Gardner R; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Talleur AC; Department of Bone Marrow Transplant, St. Jude Children's Research Hospital, Memphis, Tennessee., Shah NN; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Rossoff J; Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

Publikováno v: Transplantation and cellular therapy [Transplant Cell Ther] 2024 Jan; Vol. 30 (1), pp. 38-55. Date of Electronic Publication: 2023 Oct 10.

Mediport use as an acceptable standard for CAR T cell infusion.

Autor: Eylon M; College of Medicine, Central Michigan University, Mount Pleasant, MI, United States., Prabhu S; Department of Pediatrics, Division of Hematology and Oncology, Stanford University School of Medicine, Palo Alto, CA, United States., John S; Department of Pediatrics, The University of Texas Southwestern Medical Center/Children's Health, Dallas, TX, United States., King MJM; College of Medicine, Central Michigan University, Mount Pleasant, MI, United States., Bhatt D; Department for Biology, Stanford University, Palo Alto, CA, United States., Curran KJ; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, United States., Erickson C; Department of Pediatrics, Division of Hematology and Oncology, Stanford University School of Medicine, Palo Alto, CA, United States., Karras NA; Department of Pediatrics, City of Hope National Medical Center, Duarte, CA, United States., Phillips CL; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, United States.; Cincinnati Children's Hospital Medical Center, Cancer and Blood Disease Institute, Cincinnati, OH, United States., Satwani P; Division of Pediatric Hematology, Oncology and Stem Cell Transplant, Department of Pediatrics, Columbia University Medical Center, New York, NY, United States., Hermiston M; University of California, San Francisco Benioff Children's Hospital, San Francisco, CA, United States., Southworth E; University of California, San Francisco Benioff Children's Hospital, San Francisco, CA, United States., Baumeister SHC; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Dana Farber/Boston Children's Hospital, Boston, MA, United States., Talano JA; Department of Pediatric Hematology Oncology, Medical College of Wisconsin, Milwaukee, WI, United States., MacMillan ML; Department of Pediatrics, Division of Pediatric Blood and Marrow Transplantation, University of Minnesota Medical School, Minneapolis, MN, United States., Rossoff J; Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States., Bonifant CL; Sidney Kimmel Comprehensive Cancer Center, Division of Pediatric Oncology, Philadelphia, MD, United States., Myers GD; Children's Mercy Hospital, University of Missouri, Columbia, MO, United States., Rouce RH; Bone Marrow Transplant/Stem Cell Transplant Program, Texas Children's Cancer Center, Houston, TX, United States., Toner K; Division of Blood and Marrow Transplant and CAR-T Program, Children's National Hospital, Northwest, DC, United States., Driscoll TA; Pediatric Transplant and Cellular Therapy, Duke Children's Hospital & Health Center, Durham, NC, United States., Katsanis E; Department of Pediatrics, University of Arizona, AZ, United States., Salzberg DB; Center for Cancer and Blood Disorder, Phoenix Children's Hospital, Phoenix, AZ, United States., Schiff D; Division of Hematology/Oncology, Rady Children's Hospital, San Diego, CA, United States., De Oliveira SN; Department of Pediatrics, University of California Los Angeles (UCLA) Mattel Children's Hospital, Los Angeles, CA, United States., Capitini CM; Department of Pediatrics and Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States., Pacenta HL; Cook Children's Hematology and Oncology, Cook Children's Hospital, Fort Worth, TX, United States.; Department of Pediatrics, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States., Pfeiffer T; Saint Louis Children's Hospital One Children's Pl, Saint Louis, MO, United States., Shah NC; Yale Medicine, Yale University and Yale New Haven Children's Hospital New Haven, New Haven, CT, United States., Huynh V; Pediatric Oncology, CHOC Children's Hospital of Orange County, Orange County, CA, United States., Skiles JL; Riley Children Health, Indiana University Health, IN, United States., Fraint E; Division of Pediatric Hematology, Oncology, and Cellular Therapy, The Children's Hospital at Montefiore, Bronx, NY, United States., McNerney KO; Department of Pediatrics, John Hopkins All Children's Hospital, St. Petersburg, FL, United States., Quigg TC; Section of Pediatric BMT and Cellular Therapy, Helen DeVos Children's Hospital, Grand Rapids, MI, United States., Krueger J; Division of Hematology/Oncology, The Hospital For Sick Children, Toronto, ON, Canada., Ligon JA; Health Pediatric Blood & Marrow Transplant and Cellular Therapy, University of Florida, Gainesville, FL, United States., Fabrizio VA; Colorado Children's Hospital, University of Colorado, Boulder, CO, United States., Baggott C; Department of Pediatrics, Division of Hematology and Oncology, Stanford University School of Medicine, Palo Alto, CA, United States., Laetsch TW; Department of Pediatrics, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States., Schultz LM; Department of Pediatrics, Division of Hematology and Oncology, Stanford University School of Medicine, Palo Alto, CA, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Oct 27; Vol. 14, pp. 1239132. Date of Electronic Publication: 2023 Oct 27 (Print Publication: 2023).

Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-Like Syndrome.

Autor: Hines MR; Department of Pediatric Medicine, Division of Critical Care, St. Jude Children's Research Hospital, Memphis, Tennessee., Knight TE; Pediatric Hematology and Oncology, Seattle Children's Hospital and the University of Washington School of Medicine, Seattle, Washington., McNerney KO; Cancer and Blood Disorders Institute, Johns Hopkins All Children's Hospital, St. Petersburg, Florida., Leick MB; Cellular Immunotherapy Program and Blood and Marrow Transplant Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts., Jain T; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland., Ahmed S; Departments of Lymphoma and Myeloma and Stem Cell Transplantation, The University of Texas MD Anderson Cancer Center, Houston, Texas., Frigault MJ; Cellular Immunotherapy Program and Blood and Marrow Transplant Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts., Hill JA; Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Center, Seattle, Washington., Jain MD; Moffitt Cancer Center, Tampa, Florida., Johnson WT; Department of Medicine, Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, New York., Lin Y; Division Hematology-Oncology and Blood and Marrow Transplantation Program, Mayo Clinic, Rochester, Minnesota., Mahadeo KM; Pediatric Transplantation and Cellular Therapy, Duke University, Durham, North Carolina., Maron GM; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, and Department of Pediatrics, University of Tennessee Health Science Center College of Medicine, Memphis, Tennessee., Marsh RA; University of Cincinnati, and Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Neelapu SS; Departments of Lymphoma and Myeloma and Stem Cell Transplantation, The University of Texas MD Anderson Cancer Center, Houston, Texas., Nikiforow S; Division of Hematologic Oncology, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts., Ombrello AK; Inflammatory Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland., Shah NN; Bone Marrow Transplant and Cellular Therapy Program, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin., Talleur AC; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, Tennessee and Department of Pediatrics, University of Tennessee Health Science Center College of Medicine, Memphis, Tennessee., Turicek D; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Vatsayan A; Division of Blood and Marrow Transplantation, Children's National Health System, Washington, District of Columbia., Wong SW; UCSF Health Division of Hematology and Oncology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California., Maus MV; Cellular Immunotherapy Program and Blood and Marrow Transplant Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts., Komanduri KV; UCSF Health Division of Hematology and Oncology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California., Berliner N; Brigham and Women's Hospital, Boston, Massachusetts., Henter JI; Division of Pediatric Oncology and Surgery, Department of Women's and Children's Health, Karolinska Institute, and Department of Paediatric Oncology, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden., Perales MA; Department of Medicine, Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, New York., Frey NV; Division of Hematology-Oncology, Abramson Cancer Center and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Teachey DT; Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Frank MJ; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California., Shah NN; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Electronic address: Nirali.Shah@nih.gov.

Publikováno v: Transplantation and cellular therapy [Transplant Cell Ther] 2023 Jul; Vol. 29 (7), pp. 438.e1-438.e16. Date of Electronic Publication: 2023 Mar 09.