Výsledky vyhledávání - "McNancy Kang"

Akademický článek

Induction of Tolerogenic Dendritic Cells by a PEGylated TLR7 Ligand for Treatment of Type 1 Diabetes.

Autor: Tomoko Hayashi, Shiyin Yao, Brian Crain, Victor J Promessi, Luke Shyu, Caroline Sheng, McNancy Kang, Howard B Cottam, Dennis A Carson, Maripat Corr

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0129867 (2015)

Autoimmune diabetes mellitus (DM) results from the destruction of pancreatic islet cells by activated T lymphocytes, which have been primed by activated dendritic cells (DC). Individualized therapy with ex vivo DC manipulation and reinfusion has been

Externí odkaz: https://doaj.org/article/a0deb4f5bc424838a90918bde039bbae

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Histone Deacetylase Inhibition with Panobinostat Combined with Intensive Induction Chemotherapy in Older Patients with Acute Myeloid Leukemia: Phase I Study Results

Autor: Charalambos Andreadis, Scott Thomas, McNancy Kang, Aaron C Logan, Matthew J. Wieduwilt, Nela Pawlowska, Karin M.L. Gaensler, Pamela N. Munster, Thomas Martin, Wanda Boyer, Peter H. Sayre, Lloyd E. Damon, Rebecca L. Olin, Kirsten Anderson

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 25(16)

Purpose: The histone deacetylase (HDAC) inhibitor panobinostat potentiates anthracycline and cytarabine cytotoxicity in acute myeloid leukemia (AML) cells. We hypothesized that panobinostat prior to and during induction chemotherapy would be tolerabl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ef01328d3defea424a5b9ab6bfa6dc
https://pubmed.ncbi.nlm.nih.gov/31152020

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Inhibition of keratinocyte proliferation by phospholipid-conjugates of a TLR7 ligand in a Myc-induced hyperplastic actinic keratosis model in the absence of systemic side effects

Autor: Victor J. Promessi, Brian Crain, McNancy Kang, Shiyin Yao, Tomoko Hayashi, Dennis A. Carson, Johanna Holldack, Roberto Maj, Vina Keophilaone, Nadia Passini, Alcide Barberis, Howard B. Cottam, Emanuela Mura, Ricardo Ochoa

Publikováno v: European Journal of Dermatology. 23:618-628

Background. The Toll-like receptor 7 (TLR7) activator imiquimod (IMQ) is safe and effective in treating actinic keratosis; however, an intermittent treatment regimen is necessary because of excessive local reactions. Objectives. To evaluate in vitro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b74491cb4ecc451ddf673d1a8be4cd67
https://doi.org/10.1684/ejd.2013.2155

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