Zobrazeno 1 - 10 of 76 pro vyhledávání: '"McNamara, CW"'
2
Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease
Autor: Arkin, Michelle, Khare, S, Roach, SL, Barnes, SW, Hoepfner, D, Walker, JR, Chatterjee, AK, Neitz, RJ, Arkin, MR, McNamara, CW, Ballard, J
Publikováno v: Arkin, Michelle; Khare, S; Roach, SL; Barnes, SW; Hoepfner, D; Walker, JR; et al.(2015). Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6jq5m37t
© 2015 Khare et al.Unbiased phenotypic screens enable identification of small molecules that inhibit pathogen growth by unanticipated mechanisms. These small molecules can be used as starting points for drug discovery programs that target such mecha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::fe967363ab4e29ba0b58056b00a4a3f8
http://www.escholarship.org/uc/item/6jq5m37t
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3
Akademický článek
PRM22 - Establishing Equivalence of Electronic Clinician-Reported Outcome Measures
Autor: Feaster, T, Fuller, R, Mcnamara, CW, Lenderking, WR, Miller, DS, Sabatino, D, Butler, A
Publikováno v: In Value in Health May 2016 19(3):A75-A75
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4
Akademický článek
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5
Akademický článek
An oral non-covalent non-peptidic inhibitor of SARS-CoV-2 Mpro ameliorates viral replication and pathogenesis in vivo.
Autor: Zhou NE; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA., Tang S; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA., Bian X; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA., Parai MK; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA., Krieger IV; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA., Flores A; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA., Jaiswal PK; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA., Bam R; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA., Wood JL; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA., Shi Z; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA., Stevens LJ; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA., Scobey T; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Diefenbacher MV; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Moreira FR; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Baric TJ; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Acharya A; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA., Shin J; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA., Rathi MM; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA., Wolff KC; Calibr-Skaggs Institute for Innovative Medicine, La Jolla, CA 92037, USA., Riva L; Calibr-Skaggs Institute for Innovative Medicine, La Jolla, CA 92037, USA., Bakowski MA; Calibr-Skaggs Institute for Innovative Medicine, La Jolla, CA 92037, USA., McNamara CW; Calibr-Skaggs Institute for Innovative Medicine, La Jolla, CA 92037, USA., Catanzaro NJ; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Graham RL; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Schultz DC; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, USA., Cherry S; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, USA; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA., Kawaoka Y; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53711, USA., Halfmann PJ; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53711, USA., Baric RS; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Denison MR; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA., Sheahan TP; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: sheahan@email.unc.edu., Sacchettini JC; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77840, USA. Electronic address: sacchett@tamu.edu.
Publikováno v: Cell reports [Cell Rep] 2024 Nov 05; Vol. 43 (11), pp. 114929. Date of Electronic Publication: 2024 Nov 05.
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6
Akademický článek
High Throughput Repurposing Screen Reveals Compounds with Activity Against Toxoplasma gondii Bradyzoites.
Autor: Uddin T; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA., Xia J; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA., Fu Y; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA., McNamara CW; Calibr at Scripps Research, La Jolla, California, USA., Chatterjee AK; Calibr at Scripps Research, La Jolla, California, USA., Sibley LD; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.
Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 22. Date of Electronic Publication: 2024 Aug 22.
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7
Akademický článek
Identification of mCMQ069, a novel antimalarial with potential for a single-dose cure and/or 28-day chemoprevention.
Autor: Gupta AK, Pedroarena J, Nazarian A, Antonova-Koch J, Weiss F, Kumpornsin K, Chi V, Woods AK, Lee KJ, Joseph SB, Li S, Brittain J, De Hostos E, Duffy J, Cooper A, Schultz PG, McNamara CW, Chatterjee AK
Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 01. Date of Electronic Publication: 2024 Jul 01.
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8
Correction to "Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead".
Autor: Elshan NGRD; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Wolff KC; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Riva L; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Woods AK; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Grabovyi G; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Wilson K; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Pedroarena J; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Ghorai S; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Nazarian A; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Weiss F; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Liu Y; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Mazumdar W; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Song L; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Okwor N; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Malvin J; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Liu D; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Bakowski MA; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Beutler N; Department of Immunology and Microbiology, The Scripps Research Institute, 10466 North Torrey Pines Road, La Jolla, California 92037, United States., Kirkpatrick MG; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Gebara-Lamb A; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Huang E; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Nguyen-Tran VTB; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Chi V; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Li S; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Rogers TF; Department of Immunology and Microbiology, The Scripps Research Institute, 10466 North Torrey Pines Road, La Jolla, California 92037, United States., McNamara CW; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Gupta AK; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Rahimi A; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Chen JJ; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Joseph SB; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States., Schultz PG; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States.; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States., Chatterjee AK; Calibr at Scripps Research Institute, 11119 North Torrey Pines Road, La Jolla, California 92037, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2024 Jun 27; Vol. 67 (12), pp. 10508-10509. Date of Electronic Publication: 2024 Jun 14.
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9
Akademický článek
A Prodrug Strategy to Reposition Atovaquone as a Long-Acting Injectable for Malaria Chemoprotection.
Autor: Gupta AK, Eliasen AM, Andahazy W, Zhou F, Henson K, Chi V, Woods AK, Joseph SB, Kuhen KL, Wisler J, Ramachandruni H, Duffy J, Burrows JN, Vadas E, Slade A, Schultz PG, McNamara CW, Chatterjee AK
Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 25. Date of Electronic Publication: 2024 Jun 25.
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10
Akademický článek
Pyridopyrimidinones as a new chemotype of calcium dependent protein kinase 1 (CDPK1) inhibitors for Cryptosporidium.
Autor: Waldron-Young E; Department of Pharmaceutical and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, United States., Wijitrmektong W; Department of Pharmaceutical and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, United States., Choi R; Department of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109, United States., Whitman GR; Department of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109, United States., Hulverson MA; Department of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109, United States., Charania R; Department of Pediatrics, Emory University and Children's Healthcare Organization of Atlanta, Atlanta, GA 30322, United States; Atlanta VA Medical Center, Decatur, GA 30033, United States., Keelaghan A; Department of Pediatrics, Emory University and Children's Healthcare Organization of Atlanta, Atlanta, GA 30322, United States; Atlanta VA Medical Center, Decatur, GA 30033, United States., Li L; Department of Pharmaceutical and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, United States., Srinual S; Department of Pharmaceutical and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, United States., Nikhar S; Department of Pharmaceutical and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, United States., McNamara CW; Calibr-Skaggs Institute for Innovative Medicines, A division of The Scripps Research Institute, La Jolla, CA 92037, United States., Love MS; Calibr-Skaggs Institute for Innovative Medicines, A division of The Scripps Research Institute, La Jolla, CA 92037, United States., Huerta L; Calibr-Skaggs Institute for Innovative Medicines, A division of The Scripps Research Institute, La Jolla, CA 92037, United States., Bakowski MA; Calibr-Skaggs Institute for Innovative Medicines, A division of The Scripps Research Institute, La Jolla, CA 92037, United States., Hu M; Department of Pharmaceutical and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, United States., Van Voorhis WC; Department of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109, United States., Mead JR; Department of Pediatrics, Emory University and Children's Healthcare Organization of Atlanta, Atlanta, GA 30322, United States; Atlanta VA Medical Center, Decatur, GA 30033, United States., Cuny GD; Department of Pharmaceutical and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, United States. Electronic address: gdcuny@central.uh.edu.
Publikováno v: Molecular and biochemical parasitology [Mol Biochem Parasitol] 2024 Jun 18; Vol. 260, pp. 111637. Date of Electronic Publication: 2024 Jun 18.
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