PON2 mediates mitochondrial dysfunction in tracheal epithelial cells in response to a quorum sensing molecule N-(-3-oxododecanoyl)-l-homoserine lactone.

Autor: Whitt AG; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY, U.S.A.; Experimental Therapeutics Group, Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY, U.S.A., Meng S; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY, U.S.A.; Experimental Therapeutics Group, Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY, U.S.A., Jin JZ; Experimental Therapeutics Group, Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY, U.S.A., Conroy LR; Department of Neuroscience, College of Medicine, University of Kentucky, Lexington, KY, U.S.A.; Markey Cancer Center, University of Kentucky, Lexington, KY, U.S.A., McNally LA; Diabetes and Obesity Center, Division of Environmental Medicine, Diabetes and Obesity Center, Department of Medicine, University of Louisville, Louisville, KY, U.S.A., Burlison JA; Experimental Therapeutics Group, Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY, U.S.A., Hill BG; Diabetes and Obesity Center, Division of Environmental Medicine, Diabetes and Obesity Center, Department of Medicine, University of Louisville, Louisville, KY, U.S.A.; Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, KY, U.S.A., Clem BF; Experimental Therapeutics Group, Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY, U.S.A.; Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, KY, U.S.A., White C; Department of Physiology and Biophysics, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, U.S.A., Li C; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY, U.S.A.; Experimental Therapeutics Group, Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY, U.S.A.

Publikováno v: The Biochemical journal [Biochem J] 2022 Oct 14; Vol. 479 (19), pp. 2013-2034.

Considerations for using isolated cell systems to understand cardiac metabolism and biology.

Autor: McNally LA; Department of Medicine, Division of Environmental Medicine, Christina Lee Brown Envirome Institute, Diabetes and Obesity Center, University of Louisville, Louisville, KY, USA., Altamimi TR; Department of Medicine, Division of Environmental Medicine, Christina Lee Brown Envirome Institute, Diabetes and Obesity Center, University of Louisville, Louisville, KY, USA., Fulghum K; Department of Medicine, Division of Environmental Medicine, Christina Lee Brown Envirome Institute, Diabetes and Obesity Center, University of Louisville, Louisville, KY, USA., Hill BG; Department of Medicine, Division of Environmental Medicine, Christina Lee Brown Envirome Institute, Diabetes and Obesity Center, University of Louisville, Louisville, KY, USA. Electronic address: bradford.hill@louisville.edu.

Publikováno v: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2021 Apr; Vol. 153, pp. 26-41. Date of Electronic Publication: 2020 Dec 21.

Mitochondria-associated lactate dehydrogenase is not a biologically significant contributor to bioenergetic function in murine striated muscle.

Autor: Fulghum KL; Diabetes and Obesity Center, Envirome Institute, Department of Medicine, University of Louisville, Louisville, KY, USA; Department of Physiology and Biophysics, University of Louisville, Louisville, KY, USA., Rood BR; Diabetes and Obesity Center, Envirome Institute, Department of Medicine, University of Louisville, Louisville, KY, USA., Shang VO; Diabetes and Obesity Center, Envirome Institute, Department of Medicine, University of Louisville, Louisville, KY, USA; Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, KY, USA., McNally LA; Diabetes and Obesity Center, Envirome Institute, Department of Medicine, University of Louisville, Louisville, KY, USA., Riggs DW; Diabetes and Obesity Center, Envirome Institute, Department of Medicine, University of Louisville, Louisville, KY, USA; Department of Bioinformatics and Biostatistics, University of Louisville, Louisville, KY, USA., Zheng YT; Diabetes and Obesity Center, Envirome Institute, Department of Medicine, University of Louisville, Louisville, KY, USA., Hill BG; Diabetes and Obesity Center, Envirome Institute, Department of Medicine, University of Louisville, Louisville, KY, USA; Department of Physiology and Biophysics, University of Louisville, Louisville, KY, USA; Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, KY, USA. Electronic address: bradford.hill@louisville.edu.

Publikováno v: Redox biology [Redox Biol] 2019 Jun; Vol. 24, pp. 101177. Date of Electronic Publication: 2019 Mar 22.

Exercise-Induced Changes in Glucose Metabolism Promote Physiological Cardiac Growth.

Autor: Gibb AA; Institute of Molecular Cardiology (A.A.G., Y.Z., L.A.M., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.).; Diabetes and Obesity Center (A.A.G., Y.Z., L.A.M., D.O., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.).; Department of Physiology (A.A.G., B.G.H.)., Epstein PN; Department of Pediatrics (P.N.E.)., Uchida S; Cardiovascular Innovation Institute (S.U.)., Zheng Y; Institute of Molecular Cardiology (A.A.G., Y.Z., L.A.M., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.).; Diabetes and Obesity Center (A.A.G., Y.Z., L.A.M., D.O., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.)., McNally LA; Institute of Molecular Cardiology (A.A.G., Y.Z., L.A.M., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.).; Diabetes and Obesity Center (A.A.G., Y.Z., L.A.M., D.O., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.)., Obal D; Diabetes and Obesity Center (A.A.G., Y.Z., L.A.M., D.O., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.).; Department of Anesthesiology (D.O.)., Katragadda K; Institute of Molecular Cardiology (A.A.G., Y.Z., L.A.M., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.).; Diabetes and Obesity Center (A.A.G., Y.Z., L.A.M., D.O., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.)., Trainor P; Institute of Molecular Cardiology (A.A.G., Y.Z., L.A.M., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.).; Diabetes and Obesity Center (A.A.G., Y.Z., L.A.M., D.O., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.)., Conklin DJ; Institute of Molecular Cardiology (A.A.G., Y.Z., L.A.M., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.).; Diabetes and Obesity Center (A.A.G., Y.Z., L.A.M., D.O., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.)., Brittian KR; Institute of Molecular Cardiology (A.A.G., Y.Z., L.A.M., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.).; Diabetes and Obesity Center (A.A.G., Y.Z., L.A.M., D.O., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.)., Tseng MT; Department of Anatomy and Neuroscience (M.T.T.)., Wang J; University of Louisville, KY. Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (J.W.)., Jones SP; Institute of Molecular Cardiology (A.A.G., Y.Z., L.A.M., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.).; Diabetes and Obesity Center (A.A.G., Y.Z., L.A.M., D.O., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.)., Bhatnagar A; Institute of Molecular Cardiology (A.A.G., Y.Z., L.A.M., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.).; Diabetes and Obesity Center (A.A.G., Y.Z., L.A.M., D.O., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.)., Hill BG; Institute of Molecular Cardiology (A.A.G., Y.Z., L.A.M., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.) bradford.hill@louisville.edu.; Diabetes and Obesity Center (A.A.G., Y.Z., L.A.M., D.O., K.K., P.T., D.J.C., K.R.B., S.P.J., A.B., B.G.H.).; Department of Physiology (A.A.G., B.G.H.).

Publikováno v: Circulation [Circulation] 2017 Nov 28; Vol. 136 (22), pp. 2144-2157. Date of Electronic Publication: 2017 Aug 31.

FVB/NJ Mice Are a Useful Model for Examining Cardiac Adaptations to Treadmill Exercise.

Autor: Gibb AA; Department of Medicine, Institute of Molecular Cardiology, University of LouisvilleLouisville, KY, USA; Diabetes and Obesity Center, University of LouisvilleLouisville, KY, USA; Department of Physiology, University of LouisvilleLouisville, KY, USA., McNally LA; Department of Medicine, Institute of Molecular Cardiology, University of LouisvilleLouisville, KY, USA; Diabetes and Obesity Center, University of LouisvilleLouisville, KY, USA., Riggs DW; Department of Medicine, Institute of Molecular Cardiology, University of LouisvilleLouisville, KY, USA; Diabetes and Obesity Center, University of LouisvilleLouisville, KY, USA., Conklin DJ; Department of Medicine, Institute of Molecular Cardiology, University of LouisvilleLouisville, KY, USA; Diabetes and Obesity Center, University of LouisvilleLouisville, KY, USA., Bhatnagar A; Department of Medicine, Institute of Molecular Cardiology, University of LouisvilleLouisville, KY, USA; Diabetes and Obesity Center, University of LouisvilleLouisville, KY, USA; Department of Physiology, University of LouisvilleLouisville, KY, USA; Department of Biochemistry and Molecular Genetics, University of LouisvilleLouisville, KY, USA., Hill BG; Department of Medicine, Institute of Molecular Cardiology, University of LouisvilleLouisville, KY, USA; Diabetes and Obesity Center, University of LouisvilleLouisville, KY, USA; Department of Physiology, University of LouisvilleLouisville, KY, USA; Department of Biochemistry and Molecular Genetics, University of LouisvilleLouisville, KY, USA.

Publikováno v: Frontiers in physiology [Front Physiol] 2016 Dec 21; Vol. 7, pp. 636. Date of Electronic Publication: 2016 Dec 21 (Print Publication: 2016).