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Ca2+/calmodulin dependent protein kinase II (CaMKII) is a central mediator of Ca2+-induced signalling in the heart and regulates both normal cardiac physiology and pathology. Sunitinib malate is an oral Type I tyrosine kinase inhibitor (TKI) known to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::f24d207827ddcb7b9c91e2cc64d66b96
https://strathprints.strath.ac.uk/72649/1/McMullen_etal_Heart_2020_Sunitinib_mediates_mitochondrial_ROS_production.pdf
https://strathprints.strath.ac.uk/72649/1/McMullen_etal_Heart_2020_Sunitinib_mediates_mitochondrial_ROS_production.pdf
Autor:
Totten JD; King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, UK., Alhadrami HA; King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Jiffri EH; King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia., McMullen CJ; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, UK., Seib FP; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, UK; EPSRC Future Manufacturing Research Hub for Continuous Manufacturing and Advanced Crystallisation (CMAC), University of Strathclyde, Technology and Innovation Centre, Glasgow G1 1RD, UK., Carswell HVO; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, UK. Electronic address: hilary.carswell@strath.ac.uk.
Publikováno v:
Trends in biotechnology [Trends Biotechnol] 2022 Jun; Vol. 40 (6), pp. 708-720. Date of Electronic Publication: 2021 Nov 20.
Autor:
McMullen CJ; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom., Chalmers S; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom., Wood R; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom., Cunningham MR; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom., Currie S; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.
Publikováno v:
Frontiers in cardiovascular medicine [Front Cardiovasc Med] 2021 Feb 01; Vol. 7, pp. 630480. Date of Electronic Publication: 2021 Feb 01 (Print Publication: 2020).