The anti-angiogenic agent fumagillin covalently modifies a conserved active-site histidine in the Escherichia coli methionine aminopeptidase

Autor: Allen M. Orville, W.T. Lowther, McMillen Da, Brian W. Matthews

Publikováno v: Proceedings of the National Academy of Sciences. 95:12153-12157

Methionine aminopeptidase (MetAP) exists in two forms (type I and type II), both of which remove the N-terminal methionine from proteins. It previously has been shown that the type II enzyme is the molecular target of fumagillin and ovalicin, two epo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e7c9402eb50ca7b83d458d7fb5567c
https://doi.org/10.1073/pnas.95.21.12153

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Increasing the efficiency of bacterial transcription simulations: When to exclude the genome without loss of accuracy

Autor: McMillen David R, Dong Guang, Iafolla Marco AJ

Publikováno v: BMC Bioinformatics, Vol 9, Iss 1, p 373 (2008)

Abstract Background Simulating the major molecular events inside an Escherichia coli cell can lead to a very large number of reactions that compose its overall behaviour. Not only should the model be accurate, but it is imperative for the experimente

Externí odkaz: https://doaj.org/article/64968f2bca2345afb1d7de7b33e17d8d

Connecting single-cell transcriptomes to projectomes in mouse visual cortex.

Autor: Sorensen SA; Allen Institute for Brain Science., Gouwens NW; Allen Institute for Brain Science., Wang Y; Allen Institute for Brain Science., Mallory M; Allen Institute for Brain Science., Budzillo A; Allen Institute for Brain Science., Dalley R; Allen Institute for Brain Science., Lee B; Allen Institute for Brain Science., Gliko O; Allen Institute for Brain Science., Kuo HC; Allen Institute for Brain Science., Kuang X; School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China., Mann R; Allen Institute for Brain Science., Ahmadinia L; Allen Institute for Brain Science., Alfiler L; Allen Institute for Brain Science., Baftizadeh F; Allen Institute for Brain Science., Baker K; Allen Institute for Brain Science., Bannick S; Allen Institute for Brain Science., Bertagnolli D; Allen Institute for Brain Science., Bickley K; Allen Institute for Brain Science., Bohn P; Allen Institute for Brain Science., Brown D; Allen Institute for Brain Science., Bomben J; Allen Institute for Brain Science., Brouner K; Allen Institute for Brain Science., Chen C; School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China., Chen K; School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China., Chvilicek M; Allen Institute for Brain Science., Collman F; Allen Institute for Brain Science., Daigle T; Allen Institute for Brain Science., Dawes T; Allen Institute for Brain Science., de Frates R; Allen Institute for Brain Science., Dee N; Allen Institute for Brain Science., DePartee M; Allen Institute for Brain Science., Egdorf T; Allen Institute for Brain Science., El-Hifnawi L; Allen Institute for Brain Science., Enstrom R; Allen Institute for Brain Science., Esposito L; Allen Institute for Brain Science., Farrell C; Allen Institute for Brain Science., Gala R; Allen Institute for Brain Science., Glomb A; Allen Institute for Brain Science., Gamlin C; Allen Institute for Brain Science., Gary A; Allen Institute for Brain Science., Goldy J; Allen Institute for Brain Science., Gu H; Allen Institute for Brain Science., Hadley K; Allen Institute for Brain Science., Hawrylycz M; Allen Institute for Brain Science., Henry A; Allen Institute for Brain Science., Hill D; Allen Institute for Brain Science., Hirokawa KE; Allen Institute for Brain Science., Huang Z; School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China., Johnson K; Allen Institute for Brain Science., Juneau Z; Allen Institute for Brain Science., Kebede S; Allen Institute for Brain Science., Kim L; Allen Institute for Brain Science., Lee C; Allen Institute for Brain Science., Lesnar P; Allen Institute for Brain Science., Li A; Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MoE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, China.; HUST-Suzhou Institute for Brainsmatics, JITRI Institute for Brainsmatics, Suzhou, China., Glomb A; Allen Institute for Brain Science., Li Y; School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China., Liang E; Allen Institute for Brain Science., Link K; Allen Institute for Brain Science., Maxwell M; Allen Institute for Brain Science., McGraw M; Allen Institute for Brain Science., McMillen DA; Allen Institute for Brain Science., Mukora A; Allen Institute for Brain Science., Ng L; Allen Institute for Brain Science., Ochoa T; Allen Institute for Brain Science., Oldre A; Allen Institute for Brain Science., Park D; Allen Institute for Brain Science., Pom CA; Allen Institute for Brain Science., Popovich Z; University of Washington, Dept. of Computer Science and Engineering., Potekhina L; Allen Institute for Brain Science., Rajanbabu R; Allen Institute for Brain Science., Ransford S; Allen Institute for Brain Science., Reding M; Allen Institute for Brain Science., Ruiz A; Allen Institute for Brain Science., Sandman D; Allen Institute for Brain Science., Siverts L; Allen Institute for Brain Science., Smith KA; Allen Institute for Brain Science., Stoecklin M; Allen Institute for Brain Science., Sulc J; Allen Institute for Brain Science., Tieu M; Allen Institute for Brain Science., Ting J; Allen Institute for Brain Science., Trinh J; Allen Institute for Brain Science., Vargas S; Allen Institute for Brain Science., Vumbaco D; Allen Institute for Brain Science., Walker M; Allen Institute for Brain Science., Wang M; Allen Institute for Brain Science., Wanner A; Ariadne.ai., Waters J; Allen Institute for Brain Science., Williams G; Allen Institute for Brain Science., Wilson J; Allen Institute for Brain Science., Xiong W; School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China., Lein E; Allen Institute for Brain Science., Berg J; Allen Institute for Brain Science., Kalmbach B; Allen Institute for Brain Science., Yao S; Allen Institute for Brain Science., Gong H; Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MoE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, China.; HUST-Suzhou Institute for Brainsmatics, JITRI Institute for Brainsmatics, Suzhou, China., Luo Q; State Key Laboratory of Digital Medical Engineering, School of Biomedical Engineering, Hainan University, Haikou, China., Ng L; Allen Institute for Brain Science., Sümbül U; Allen Institute for Brain Science., Jarsky T; Allen Institute for Brain Science., Yao Z; Allen Institute for Brain Science., Tasic B; Allen Institute for Brain Science., Zeng H; Allen Institute for Brain Science.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Nov 26. Date of Electronic Publication: 2023 Nov 26.

Biotechnology core laboratories: An overview.

Autor: McMillen DA; Institute of Molecular Biology, University of Oregon, Eugene, OR 97403, USA. mcmillen@molbio.uoregon.edu, Bibbs L, Denslow N, Ivanetich KM, Naeve C, Niece RL, Tindall S

Publikováno v: Journal of biomolecular techniques : JBT [J Biomol Tech] 2000 Mar; Vol. 11 (1), pp. 1-11.