PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma

Autor: Fons NR, Sundaram RK, Breuer GA, Peng S, McLean RL, Kalathil AN, Schmidt MS, Carvalho DM, Mackay A, Jones C, Carcaboso AM, Nazarian J, Berens ME, Brenner C, Bindra RS

Publikováno v: NATURE COMMUNICATIONS
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

Pediatric high-grade gliomas are among the deadliest of childhood cancers due to limited knowledge of early driving events in their gliomagenesis and the lack of effective therapies available. In this study, we investigate the oncogenic role of PPM1D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::edc607a652129b86ff2bf9f8320ded59
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=16561

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Atypical Community-Acquired Pneumonia: Concurrent Infection With Chlamydia psittaci and Mycobacterium tuberculosis

Autor: McLean Rl, Peacock Je, Alford Pt, Wheeler Rr

Publikováno v: Southern Medical Journal. 80:402-403

We have presented a case of combined pulmonary infection with Chlamydia psittaci and Mycobacterium tuberculosis, both documented by culture of lymph nodes and respiratory secretions. We describe it not only as an unusual occurrence, but also to illus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebd409ec9e18d66dbd26bbc121085ab
https://doi.org/10.1097/00007611-198703000-00038

Autism Heterogeneity in a Densely Sampled U.S. Population: Results From the First 1,000 Participants in the RI-CART Study.

Autor: McCormick CEB; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island., Kavanaugh BC; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island.; Hassenfeld Child Health Innovation Institute, Brown University, Providence, Rhode Island., Sipsock D; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island., Righi G; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island.; Hassenfeld Child Health Innovation Institute, Brown University, Providence, Rhode Island., Oberman LM; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island., Moreno De Luca D; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island.; Hassenfeld Child Health Innovation Institute, Brown University, Providence, Rhode Island., Gamsiz Uzun ED; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Pathology and Laboratory Medicine, Alpert Medical School of Brown University, Providence, Rhode Island.; Center for Computational Molecular Biology, Brown University, Providence, Rhode Island., Best CR; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island.; Hassenfeld Child Health Innovation Institute, Brown University, Providence, Rhode Island., Jerskey BA; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island., Quinn JG; The Autism Project, Johnston, Rhode Island., Jewel SB; The Autism Project, Johnston, Rhode Island., Wu PC; Department of Pediatrics, Alpert Medical School of Brown University, Providence, Rhode Island.; Rhode Island Hospital/Hasbro Children's Hospital, Providence, Rhode Island., McLean RL; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island., Levine TP; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island.; Brown Center for the Study of Children at Risk, Women & Infants Hospital, Providence, Rhode Island., Tokadjian H; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island.; Brown Center for the Study of Children at Risk, Women & Infants Hospital, Providence, Rhode Island., Perkins KA; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island., Clarke EB; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island.; Hassenfeld Child Health Innovation Institute, Brown University, Providence, Rhode Island., Dunn B; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island., Gerber AH; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island., Tenenbaum EJ; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island.; Brown Center for the Study of Children at Risk, Women & Infants Hospital, Providence, Rhode Island., Anders TF; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island., Sheinkopf SJ; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island.; Hassenfeld Child Health Innovation Institute, Brown University, Providence, Rhode Island.; Department of Pediatrics, Alpert Medical School of Brown University, Providence, Rhode Island.; Brown Center for the Study of Children at Risk, Women & Infants Hospital, Providence, Rhode Island., Morrow EM; Emma Pendleton Bradley Hospital, East Providence, Rhode Island.; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island.; Hassenfeld Child Health Innovation Institute, Brown University, Providence, Rhode Island.; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island.; Center for Translational Neuroscience, Robert J. and Nancy D. Carney Institute for Brain Science and Brown Institute for Translational Science, Brown University, Providence, Rhode Island.

Publikováno v: Autism research : official journal of the International Society for Autism Research [Autism Res] 2020 Mar; Vol. 13 (3), pp. 474-488. Date of Electronic Publication: 2020 Jan 20.

Genetic and phenotypic diversity of NHE6 mutations in Christianson syndrome.

Autor: Pescosolido MF; Department of Molecular Biology, Cell Biology, and Biochemistry and Laboratory for Molecular Medicine, Institute for Brain Science, Brown University, Providence, RI; Developmental Disorders Genetics Research Program, Emma Pendleton Bradley Hospital and Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, East Providence, RI., Stein DM, Schmidt M, El Achkar CM, Sabbagh M, Rogg JM, Tantravahi U, McLean RL, Liu JS, Poduri A, Morrow EM

Publikováno v: Annals of neurology [Ann Neurol] 2014 Oct; Vol. 76 (4), pp. 581-93. Date of Electronic Publication: 2014 Sep 19.