IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1.

Autor: Sacheck, Jennifer M., Ohtsuka, Akira, McLary, S. Christine, Goldberg, Alfred L.

Publikováno v: American Journal of Physiology: Endocrinology & Metabolism; Oct2004, Vol. 50 Issue 4, pE591-E601, 11p, 1 Diagram, 2 Charts, 6 Graphs

Loss of heterozygosity occurs via mitotic recombination in Trp53+/- mice and associates with mammary tumor susceptibility of the BALB/c strain.

Autor: Blackburn AC; Department of Veterinary and Animal Sciences, Paige Laboratory, University of Massachusetts, Amherst, MA 01003-6410, USA., McLary SC, Naeem R, Luszcz J, Stockton DW, Donehower LA, Mohammed M, Mailhes JB, Soferr T, Naber SP, Otis CN, Jerry DJ

Publikováno v: Cancer research [Cancer Res] 2004 Aug 01; Vol. 64 (15), pp. 5140-7.